Strut Coverage With SYNERGY Stents and Bioresorbable Vascular Scaffold in Acute Myocardial Infarction (COVER-AMI)
Acute Coronary Syndrome
About this trial
This is an interventional treatment trial for Acute Coronary Syndrome focused on measuring Acute coronary syndrome, ST (Software Test) -elevation
Eligibility Criteria
Inclusion Criteria:
- Acute coronary syndrome with ST-elevation,
- One culprit lesion eligible for percutaneous coronary intervention (PCI) with stent implantation,
- Reference vessel measuring 2.5 mm to 3.75 mm per visual estimation, without extreme vessel tortuosity,
- thrombolysis in myocardial infarction (TIMI) 3 flow before stent deployment in the target vessel,
- Patient with at least 1 lesion eligible for planned PCI next to the culprit lesion,
- Patient affiliated to the French national health care system,
- Patient agreed to participate after full information on the study (signature of an informed consent).
Exclusion Criteria:
- Acute coronary syndrome with ST-elevation,
- One culprit lesion eligible for percutaneous coronary intervention (PCI) with stent implantation,
- Reference vessel measuring 2.5 mm to 3.75 mm per visual estimation, without extreme vessel tortuosity,
- TIMI 3 flow before stent deployment in the target vessel,
- Patient with at least 1 lesion eligible for planned PCI next to the culprit lesion,
- Patient affiliated to the French national health care system,
- Patient agreed to participate after full information on the study (signature of an informed consent).
Sites / Locations
- Didier CARRIE
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
SYNERGY Stent
BVS device
The SYNERGY™ stent is a Device marked CE (European Conformity), platinum chromium coronary stent, currently developped by Boston Scientific™. This stent has been designed with the goal of providing optimal and rapid healing within the vessel using a bioabsorbable polymer to elute everolimus.
The ABSORB Everolimus-eluting Bioresorbable Vascular Scaffold (BVS 1.1, Abbott Vascular, California, USA, CE approved) is Device marked CE, currently the most studied PLA (Polylactic acid) based scaffold. It consists of PLLA (Poly I-lactic acid) backbone with 1:1 PDLLA (Poly-DL Lactic Acid) drug surface coating and a total strut thickness of 156 μm.