Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG
Coronary Heart Disease
About this trial
This is an interventional treatment trial for Coronary Heart Disease focused on measuring coronary artery bypass graft, thoracic paravertebral block
Eligibility Criteria
Inclusion Criteria:
- Heart function grade II - III (Using the cardiac function classification method formulated by American Heart Disease Institute)
- The in - hospital was treated with off pump coronary artery bypass grafting(CABG) operation and general anesthesia.
- Had a good cognition, and signed the informed consent.
- Aged between 35 and 80.
- The age, clinical examination and other generally situation of the two groups of patients had no statistical significance.
no merger of valvular disease left ventricular ejection fraction > 40%, do not need intraaortic balloon counterpulsation support, without spinal deformity, no vertebral side clearance space-occupying lesions
Exclusion Criteria:
- Combined with other blood coagulation dysfunction, serious brain, liver and kidney dysfunction, endocrine system diseases and serious infectious disease.
- Patients with severe mental disorders cannot cooperate with the treatment.
- Emergency operation
- Have taboo of Echocardiography and pulmonary catheterization by echocardiography.
- Allergic to Local anesthetics drug.
- Suspected or had alcohol, drug abuse history.
- Spinal or paravertebral lesions.
Sites / Locations
- Xiangya Hospital of Central South University
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Placebo Comparator
TPVB T2/3+T5/6+GA
TPVB T3/4+GA
GA
the group A of patients has been received bilateral thoracic paravertebral block (TPVB T2/3+T5/6) by ropivacaine(0.3%,10ml*4), before general anesthesia management
the group Bof patients has been received bilateral thoracic paravertebral block (TPVB 3/4) by ropivacaine(0.3%,10ml*4), before general anesthesia management Device: The use of Transesophageal Echocardiography(TEE)、STAT PROFILE® and Haemonetics® during the surgery
group C under control (without TPVB)program Device: The use of Transesophageal Echocardiography(TEE)、STAT PROFILE® and Haemonetics® during the surgery