Study Evaluating the Pharmacokinetics of a Single Microdose of ACD856
Cognition Disorder, Alzheimer Disease
About this trial
This is an interventional treatment trial for Cognition Disorder focused on measuring Cognition Disorder, Alzheimer's Disease
Eligibility Criteria
Inclusion Criteria: Healthy males aged >18 and <65 years. Signed and dated informed consent prior to any study-mandated procedure Willing and able to comply with study requirements. BMI >18.0 and <30.0 kg/m^2 Male subjects must be willing to use condom or be vasectomised or practice sexual abstinence to prevent pregnancy and drug exposure of a partner and refrain from donating sperm from the date of dosing until 3 months after dosing with the IMP. Clinically normal medical history, physical findings, vital signs, ECG and laboratory values at the time of screening, as judged by the Investigator. Exclusion Criteria: History of any clinically significant disease or disorder which may either put the subject at risk because of participation in the study, or influence the results or the subject's ability to participate in the study. Any planned major surgery within the duration of the study. Clinically relevant findings in laboratory parameters, ECG or vital signs at screening History of severe allergy/hypersensitivity or ongoing allergy/hypersensitivity Regular use of any prescribed or non-prescribed medication Planned treatment or treatment with another investigational drug within 3 months Current smokers or users of nicotine products. Positive screen for drugs of abuse or alcohol at screening History of alcohol abuse or excessive intake of alcohol Presence or history of drug abuse History of, or current use of, anabolic steroids. Excessive caffeine consumption Plasma donation within one month of screening or blood donation during the 3 months prior to screening.
Sites / Locations
- Uppsala University Hospital
Arms of the Study
Arm 1
Experimental
ACD856