Back to resultsStudy of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin for First-Line Treatment of Patients With Advanced NSCLC Without Actionable Genomic Alterations (AVANZAR)
Primary Purpose
NSCLC
Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Datopotamab deruxtecan
Durvalumab
Carboplatin
Pembrolizumab
Cisplatin
Pemetrexed
Paclitaxel
Sponsored by
About this trial
This is an interventional treatment trial for NSCLC focused on measuring Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), Datopotamab deruxtecan (Dato-DXd), Durvalumab, Carboplatin, Chemotherapy, Antibody-Drug Conjugate (ADC), TROP2
Eligibility Criteria
Inclusion: Participants ≥ 18 years at screening Participants with histologically or cytologically documented NSCLC that is Stage IIIB or IIIC disease not amenable for surgical resection or definitive chemoradiation or Stage IV metastatic NSCLC disease at the time of randomisation, who have not received prior chemotherapy or other systemic therapy for first-line Stage IIIB, IIIC or IV Lacks sensitising EGFR tumour tissue mutation and ALK and ROS1 rearrangements and has no documented tumour genomic alterations in NTRK, BRAF, RET, MET or other actionable driver oncogenes with approved therapies (actionable genomic alterations). ECOG PS of 0 or 1 Archival tumour tissue collected prior to signing of ICF Has adequate bone marrow reserve and organ function within 7 days before randomisation Exclusion: History of another primary malignancy except for malignancy treated with curative intent with no known active disease within 3 years before the first dose of study intervention and of low potential risk for recurrence Mixed small-cell lung cancer and NSCLC histology; sarcomatoid variant of NSCLC Persistent toxicities caused by previous anti-cancer therapy not yet improved to Grade ≤ 1 or baseline (with exceptions) Active or prior documented autoimmune, connective tissue or inflammatory disorders (with exceptions) Spinal cord compression or brain metastases unless asymptomatic, stable, not requiring steroids for at least 7 days prior to randomisation, and a minimum of 2 weeks have elapsed between the end of radiotherapy and study enrollment History of leptomeningeal carcinomatosis Clinically significant corneal disease Known active or uncontrolled hepatitis B or C virus infection Known HIV infection that is not well controlled History of non-infectious ILD/pneumonitis that required steroids, has current ILD/pneumonitis, or has suspected ILD/pneumonitis that cannot be ruled out by imaging at screening
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Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
Dato-DXd + Durvalumab + Carboplatin
Histologic-specific therapy
Arm Description
Participants will be randomized to receive 6.0mg/kg Dato-DXd plus 1120 mg durvalumab plus carboplatin area under the curve [AUC] 5 mg/mL/minute.
Non-squamous NSCLC participants will be randomized to receive 200 mg pembrolizumab plus 500 mg/m2 pemetrexed plus either AUC 5 mg/mL/minute carboplatin or 75 mg/m2 cisplatin. Squamous NSCLC participants will be randomized to receive 200 mg of pembrolizumab plus 200 mg/m2 paclitaxel plus AUC 5 or 6 mg/mL/minute carboplatin.
Outcomes
Primary Outcome Measures
Progression-Free Survival (PFS) in the TROP2 biomarker positive population
PFS is defined as time from randomisation until progression per Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST 1.1) as assessed by blinded independent central review (BICR), or death due to any cause.
Overall Survival (OS) in the TROP2 biomarker positive population
OS is defined as the time from randomisation until the date of death due to any cause.
Secondary Outcome Measures
PFS in the Intent-to-Treat (ITT) population
PFS is defined as time from randomisation until progression per RECIST 1.1 as assessed by BICR, or death due to any cause.
OS in the ITT population
OS is defined as the time from randomisation until the date of death due to any cause.
PFS in the TROP2 biomarker negative population
PFS is defined as time from randomisation until progression per RECIST 1.1 as assessed by BICR, or death due to any cause.
OS in the TROP2 biomarker negative population
OS is defined as the time from randomisation until the date of death due to any cause.
Objective Response Rate (ORR) in the TROP2 biomarker positive and ITT populations
ORR is defined as the proportion of participants who have a confirmed Complete Response (CR) or confirmed Partial Response (PR), as determined by BICR and investigator per RECIST 1.1.
Duration of Response (DoR) in the TROP2 biomarker positive and ITT populations
DoR is defined as the time from the date of first documented confirmed response until date of documented progression per RECIST 1.1, as assessed by BICR and investigator assessment or death due to any cause.
PFS in the TROP2 biomarker positive and ITT populations
PFS is defined as time from randomisation until progression per RECIST 1.1 as assessed by investigator assessment, or death due to any cause.
Pharmacokinetics of Dato-DXd when combined with durvalumab and carboplatin.
Concentration of Dato-DXd, total anti-TROP2 antibody, and MAAA-1181a in plasma and pharmacokinetic (PK) parameters (such as peak and trough concentrations, as data allow; sparse sampling).
Anti-Drug Antibody (ADA) for Dato-DXd
The immunogenicity of Dato-DXd when combined with durvalumab and carboplatin.
Time to Second Progression or Death (PFS2) in the TROP2 biomarker positive and ITT populations
PFS2 is defined as the time from randomisation to the earliest of the progression events (following the initial progression), subsequent to first subsequent therapy, or death.
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT05687266
Brief Title
Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin for First-Line Treatment of Patients With Advanced NSCLC Without Actionable Genomic Alterations
Acronym
AVANZAR
Official Title
A Phase III, Randomised, Open-label, Multicentre, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin Versus Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic NSCLC Without Actionable Genomic Alterations (D926NC00001; AVANZAR)
Study Type
Interventional
2. Study Status
Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
December 29, 2022 (Actual)
Primary Completion Date
May 20, 2027 (Anticipated)
Study Completion Date
May 20, 2027 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
AstraZeneca
4. Oversight
Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
This is a Phase III, randomized, open-label, multicenter, global study to compare the efficacy and safety of Datopotamab Deruxtecan (Dato-DXd) in combination with durvalumab and carboplatin compared with pembrolizumab in combination with histology-specific platinum-based chemotherapy as first-line treatment of adults with stage IIIB, IIIC, or IV NSCLC without actionable genomic alterations (including sensitizing EGFR mutations, and ALK and ROS1 rearrangements).
Detailed Description
Participants with locally advanced or metastatic NSCLC without actionable tumor tissue genomic alterations and confirmed to meet all eligibility criteria will be randomized in a 1:1 ratio to Dato-DXd in combination with durvalumab and carboplatin versus pembrolizumab in combination with histology-specific platinum-based chemotherapy as first-line treatment.
The primary objectives of the study are to demonstrate superiority of Dato-DXd in combination with durvalumab and carboplatin relative to pembrolizumab in combination with platinum-based chemotherapy by assessment of Progression Free Survival (PFS) by BICR and Overall Survival (OS) in first-line treatment of TROP2 biomarker positive participants.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
NSCLC
Keywords
Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), Datopotamab deruxtecan (Dato-DXd), Durvalumab, Carboplatin, Chemotherapy, Antibody-Drug Conjugate (ADC), TROP2
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Masking Description
None (Open Label)
Allocation
Randomized
Enrollment
1000 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Dato-DXd + Durvalumab + Carboplatin
Arm Type
Experimental
Arm Description
Participants will be randomized to receive 6.0mg/kg Dato-DXd plus 1120 mg durvalumab plus carboplatin area under the curve [AUC] 5 mg/mL/minute.
Arm Title
Histologic-specific therapy
Arm Type
Active Comparator
Arm Description
Non-squamous NSCLC participants will be randomized to receive 200 mg pembrolizumab plus 500 mg/m2 pemetrexed plus either AUC 5 mg/mL/minute carboplatin or 75 mg/m2 cisplatin.
Squamous NSCLC participants will be randomized to receive 200 mg of pembrolizumab plus 200 mg/m2 paclitaxel plus AUC 5 or 6 mg/mL/minute carboplatin.
Intervention Type
Drug
Intervention Name(s)
Datopotamab deruxtecan
Other Intervention Name(s)
Dato-DXd
Intervention Description
Intravenous (IV) infusion every 3 weeks (Q3W) on Day 1 of each 21-day cycle.
Intervention Type
Drug
Intervention Name(s)
Durvalumab
Other Intervention Name(s)
MEDI4736, Imfinzi
Intervention Description
Intravenous (IV) infusion every 3 weeks (Q3W) on Day 1 of each 21-day cycle.
Intervention Type
Drug
Intervention Name(s)
Carboplatin
Intervention Description
Intravenous (IV) infusion every 3 weeks on Day 1 of each 21-day cycle for up to 4 cycles.
Intervention Type
Drug
Intervention Name(s)
Pembrolizumab
Other Intervention Name(s)
Keytruda
Intervention Description
Intravenous (IV) infusion every 3 weeks (Q3W) on Day 1 of each 21-day cycle for a maximum of 35 cycles or 2 years (whichever occurs first).
Intervention Type
Drug
Intervention Name(s)
Cisplatin
Intervention Description
Intravenous (IV) infusion every 3 weeks on Day 1 of each 21-day cycle for up to 4 cycles.
Intervention Type
Drug
Intervention Name(s)
Pemetrexed
Other Intervention Name(s)
Alimta, Pemfexy
Intervention Description
Intravenous (IV) infusion every 3 weeks on Day 1 of each 21-day cycle.
Intervention Type
Drug
Intervention Name(s)
Paclitaxel
Other Intervention Name(s)
Taxol
Intervention Description
Intravenous (IV) infusion every 3 weeks on Day 1 of each 21-day cycle for up to 4 cycles.
Primary Outcome Measure Information:
Title
Progression-Free Survival (PFS) in the TROP2 biomarker positive population
Description
PFS is defined as time from randomisation until progression per Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST 1.1) as assessed by blinded independent central review (BICR), or death due to any cause.
Time Frame
Approximately 3 Years
Title
Overall Survival (OS) in the TROP2 biomarker positive population
Description
OS is defined as the time from randomisation until the date of death due to any cause.
Time Frame
Approximately 4 years
Secondary Outcome Measure Information:
Title
PFS in the Intent-to-Treat (ITT) population
Description
PFS is defined as time from randomisation until progression per RECIST 1.1 as assessed by BICR, or death due to any cause.
Time Frame
Approximately 3 years
Title
OS in the ITT population
Description
OS is defined as the time from randomisation until the date of death due to any cause.
Time Frame
Approximately 4 years
Title
PFS in the TROP2 biomarker negative population
Description
PFS is defined as time from randomisation until progression per RECIST 1.1 as assessed by BICR, or death due to any cause.
Time Frame
Approximately 3 years
Title
OS in the TROP2 biomarker negative population
Description
OS is defined as the time from randomisation until the date of death due to any cause.
Time Frame
Approximately 4 years
Title
Objective Response Rate (ORR) in the TROP2 biomarker positive and ITT populations
Description
ORR is defined as the proportion of participants who have a confirmed Complete Response (CR) or confirmed Partial Response (PR), as determined by BICR and investigator per RECIST 1.1.
Time Frame
Approximately 4 years
Title
Duration of Response (DoR) in the TROP2 biomarker positive and ITT populations
Description
DoR is defined as the time from the date of first documented confirmed response until date of documented progression per RECIST 1.1, as assessed by BICR and investigator assessment or death due to any cause.
Time Frame
Approximately 4 years
Title
PFS in the TROP2 biomarker positive and ITT populations
Description
PFS is defined as time from randomisation until progression per RECIST 1.1 as assessed by investigator assessment, or death due to any cause.
Time Frame
Approximately 3 years
Title
Pharmacokinetics of Dato-DXd when combined with durvalumab and carboplatin.
Description
Concentration of Dato-DXd, total anti-TROP2 antibody, and MAAA-1181a in plasma and pharmacokinetic (PK) parameters (such as peak and trough concentrations, as data allow; sparse sampling).
Time Frame
Approximately 4 years
Title
Anti-Drug Antibody (ADA) for Dato-DXd
Description
The immunogenicity of Dato-DXd when combined with durvalumab and carboplatin.
Time Frame
Approximately 4 years
Title
Time to Second Progression or Death (PFS2) in the TROP2 biomarker positive and ITT populations
Description
PFS2 is defined as the time from randomisation to the earliest of the progression events (following the initial progression), subsequent to first subsequent therapy, or death.
Time Frame
Approximately 4 years
Other Pre-specified Outcome Measures:
Title
Safety of Dato-DXd in combination with durvalumab and carboplatin
Description
Safety and tolerability will be evaluated in terms of AEs (graded by CTCAE Version 5.0).
Time Frame
Approximately 4 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
130 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion:
Participants ≥ 18 years at screening
Participants with histologically or cytologically documented NSCLC that is Stage IIIB or IIIC disease not amenable for surgical resection or definitive chemoradiation or Stage IV metastatic NSCLC disease at the time of randomisation, who have not received prior chemotherapy or other systemic therapy for first-line Stage IIIB, IIIC or IV
Lacks sensitising EGFR tumour tissue mutation and ALK and ROS1 rearrangements and has no documented tumour genomic alterations in NTRK, BRAF, RET, MET or other actionable driver oncogenes with approved therapies (actionable genomic alterations).
ECOG PS of 0 or 1
Archival tumour tissue collected prior to signing of ICF
Has adequate bone marrow reserve and organ function within 7 days before randomisation
Exclusion:
History of another primary malignancy except for malignancy treated with curative intent with no known active disease within 3 years before the first dose of study intervention and of low potential risk for recurrence
Mixed small-cell lung cancer and NSCLC histology; sarcomatoid variant of NSCLC
Persistent toxicities caused by previous anti-cancer therapy not yet improved to Grade ≤ 1 or baseline (with exceptions)
Active or prior documented autoimmune, connective tissue or inflammatory disorders (with exceptions)
Spinal cord compression or brain metastases unless asymptomatic, stable, not requiring steroids for at least 7 days prior to randomisation, and a minimum of 2 weeks have elapsed between the end of radiotherapy and study enrollment
History of leptomeningeal carcinomatosis
Clinically significant corneal disease
Known active or uncontrolled hepatitis B or C virus infection
Known HIV infection that is not well controlled
History of non-infectious ILD/pneumonitis that required steroids, has current ILD/pneumonitis, or has suspected ILD/pneumonitis that cannot be ruled out by imaging at screening
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
AstraZeneca Clinical Study Information Center
Phone
1-877-240-9479
Email
information.center@astrazeneca.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Charu Aggarwal
Organizational Affiliation
Perelman Center for Advanced Medicine
Official's Role
Study Chair
Facility Information:
Facility Name
Research Site
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85054
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85704
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hot Springs National Park
State/Province
Arkansas
ZIP/Postal Code
71913
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Springdale
State/Province
Arkansas
ZIP/Postal Code
72762
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lakewood
State/Province
California
ZIP/Postal Code
90805
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Los Angeles
State/Province
California
ZIP/Postal Code
90017
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Orange
State/Province
California
ZIP/Postal Code
92868
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Boulder
State/Province
Colorado
ZIP/Postal Code
80303
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33901
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32224
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Saint Petersburg
State/Province
Florida
ZIP/Postal Code
33705
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
West Palm Beach
State/Province
Florida
ZIP/Postal Code
33401
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Evergreen Park
State/Province
Illinois
ZIP/Postal Code
60805
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Quincy
State/Province
Illinois
ZIP/Postal Code
62301
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Fort Wayne
State/Province
Indiana
ZIP/Postal Code
46845
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Muncie
State/Province
Indiana
ZIP/Postal Code
47303
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Bettendorf
State/Province
Iowa
ZIP/Postal Code
52722
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Des Moines
State/Province
Iowa
ZIP/Postal Code
50309
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70808
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70809
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Covington
State/Province
Louisiana
ZIP/Postal Code
70433
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Duluth
State/Province
Minnesota
ZIP/Postal Code
55805
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55404
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55905
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Hannibal
State/Province
Missouri
ZIP/Postal Code
63401
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68506
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68510
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89169
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Clifton Park
State/Province
New York
ZIP/Postal Code
12065
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
East Hills
State/Province
New York
ZIP/Postal Code
11548
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
East Syracuse
State/Province
New York
ZIP/Postal Code
13057
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
West Islip
State/Province
New York
ZIP/Postal Code
11795
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Asheville
State/Province
North Carolina
ZIP/Postal Code
28806
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27103
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Canton
State/Province
Ohio
ZIP/Postal Code
44710
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43219
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Toledo
State/Province
Ohio
ZIP/Postal Code
43623
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Tulsa
State/Province
Oklahoma
ZIP/Postal Code
74134
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Portland
State/Province
Oregon
ZIP/Postal Code
97239
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Salem
State/Province
Oregon
ZIP/Postal Code
97301
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19111
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15212
Country
United States
Individual Site Status
Withdrawn
Facility Name
Research Site
City
York
State/Province
Pennsylvania
ZIP/Postal Code
17403
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Watertown
State/Province
South Dakota
ZIP/Postal Code
57201
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Knoxville
State/Province
Tennessee
ZIP/Postal Code
37916
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Memphis
State/Province
Tennessee
ZIP/Postal Code
38120
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203
Country
United States
Individual Site Status
Suspended
Facility Name
Research Site
City
Dallas
State/Province
Texas
ZIP/Postal Code
75246
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Dallas
State/Province
Texas
ZIP/Postal Code
75251
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Denton
State/Province
Texas
ZIP/Postal Code
76201
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Houston
State/Province
Texas
ZIP/Postal Code
77090
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78240
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Fairfax
State/Province
Virginia
ZIP/Postal Code
22031
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Fort Belvoir
State/Province
Virginia
ZIP/Postal Code
22060
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Henrico
State/Province
Virginia
ZIP/Postal Code
23229
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Auburn
State/Province
Washington
ZIP/Postal Code
98001
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Renton
State/Province
Washington
ZIP/Postal Code
98055
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Spokane
State/Province
Washington
ZIP/Postal Code
99202
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Tacoma
State/Province
Washington
ZIP/Postal Code
98405
Country
United States
Individual Site Status
Recruiting
Facility Name
Research Site
City
Graz
ZIP/Postal Code
8036
Country
Austria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Rankweil
ZIP/Postal Code
6830
Country
Austria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Wien
ZIP/Postal Code
1210
Country
Austria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Blumenau
ZIP/Postal Code
89010-340
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Florianópolis
ZIP/Postal Code
88034-000
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Fortaleza
ZIP/Postal Code
60336-045
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Londrina
ZIP/Postal Code
86015-520
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Porto Alegre
ZIP/Postal Code
90035-903
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sao Paulo
ZIP/Postal Code
01246-000
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sao Paulo
ZIP/Postal Code
01327-001
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sao Paulo
ZIP/Postal Code
01509-900
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sao Paulo
ZIP/Postal Code
09323-900
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Taubaté
ZIP/Postal Code
12030-200
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Vitoria
ZIP/Postal Code
29043-260
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Research Site
City
Panagyurishte
ZIP/Postal Code
4500
Country
Bulgaria
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Plovdiv
ZIP/Postal Code
4004
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Plovdiv
ZIP/Postal Code
4109
Country
Bulgaria
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Sofia
ZIP/Postal Code
1113
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sofia
ZIP/Postal Code
1330
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sofia
ZIP/Postal Code
1407
Country
Bulgaria
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Sofia
ZIP/Postal Code
1618
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Varna
ZIP/Postal Code
9010
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Research Site
City
Saint John
State/Province
New Brunswick
ZIP/Postal Code
E2L 4L2
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Brampton
State/Province
Ontario
ZIP/Postal Code
L6R 3J7
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kitchener
State/Province
Ontario
ZIP/Postal Code
N2G 1G3
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Newmarket
State/Province
Ontario
ZIP/Postal Code
L3Y 2P9
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sudbury
State/Province
Ontario
ZIP/Postal Code
P3E 5J1
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H1T 2M4
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H4A 3J1
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H4J 1C5
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
St-Jerome
State/Province
Quebec
ZIP/Postal Code
J7Z 5T3
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N 4H4
Country
Canada
Individual Site Status
Recruiting
Facility Name
Research Site
City
Beijing
ZIP/Postal Code
100010
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Beijing
ZIP/Postal Code
100029
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Beijing
ZIP/Postal Code
100037
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Beijing
ZIP/Postal Code
100039
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Beijing
ZIP/Postal Code
CN-100730
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Beijing
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Changsha
ZIP/Postal Code
410008
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Changsha
ZIP/Postal Code
410013
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Chengdu
ZIP/Postal Code
610041
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Chengdu
ZIP/Postal Code
610072
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Chongqing
ZIP/Postal Code
400037
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Guangzhou
ZIP/Postal Code
510000
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Guangzhou
ZIP/Postal Code
510100
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Hefei
ZIP/Postal Code
230601
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Jinan
ZIP/Postal Code
250021
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kunming
ZIP/Postal Code
650032
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Kunming
ZIP/Postal Code
650101
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lanzhou
ZIP/Postal Code
730000
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Liuzhou
ZIP/Postal Code
545006
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shandong
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shanghai
ZIP/Postal Code
200030
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shanghai
ZIP/Postal Code
200032
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Shanghai
ZIP/Postal Code
200080
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shantou
ZIP/Postal Code
515041
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shenyang
ZIP/Postal Code
110001
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shenzhen
ZIP/Postal Code
517108
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Shijiazhuang
ZIP/Postal Code
050020
Country
China
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Taiyuan
ZIP/Postal Code
030000
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Tianjin
ZIP/Postal Code
300060
Country
China
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Wenzhou
ZIP/Postal Code
325000
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Wuhan
ZIP/Postal Code
430030
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Wuhan
ZIP/Postal Code
430060
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Xiamen
ZIP/Postal Code
361004
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Yangzhou
ZIP/Postal Code
225001
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Zhengzhou
ZIP/Postal Code
450052
Country
China
Individual Site Status
Recruiting
Facility Name
Research Site
City
Herning
ZIP/Postal Code
7400
Country
Denmark
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Næstved
ZIP/Postal Code
4700
Country
Denmark
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Sønderborg
ZIP/Postal Code
6400
Country
Denmark
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Brest
ZIP/Postal Code
29200
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Clermont-Ferrand
ZIP/Postal Code
63000
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Creteil
ZIP/Postal Code
94010
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Montpellier
ZIP/Postal Code
34070
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Nimes
ZIP/Postal Code
30029
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Paris
ZIP/Postal Code
75018
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Saint-Quentin cedex
ZIP/Postal Code
02321
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Strasbourg Cedex
ZIP/Postal Code
67091
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Toulon Cedex 9
ZIP/Postal Code
83800
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Toulouse
ZIP/Postal Code
31059
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Tours
ZIP/Postal Code
37000
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Villefranche-sur-Saône cedex
ZIP/Postal Code
69400
Country
France
Individual Site Status
Recruiting
Facility Name
Research Site
City
Bad Berka
ZIP/Postal Code
99437
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Berlin
ZIP/Postal Code
12351
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Berlin
ZIP/Postal Code
14109
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Frankfurt A. Main
ZIP/Postal Code
60590
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Gauting
ZIP/Postal Code
82131
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Gütersloh
ZIP/Postal Code
33332
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hamburg
ZIP/Postal Code
20251
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kassel
ZIP/Postal Code
34125
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kiel
ZIP/Postal Code
24116
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Koblenz
ZIP/Postal Code
56073
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Minden
ZIP/Postal Code
32429
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Mönchengladbach
ZIP/Postal Code
41063
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Paderborn
ZIP/Postal Code
33098
Country
Germany
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Rosenheim
ZIP/Postal Code
83022
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Velbert
ZIP/Postal Code
42551
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Würzburg
ZIP/Postal Code
97074
Country
Germany
Individual Site Status
Recruiting
Facility Name
Research Site
City
Athens
ZIP/Postal Code
11527
Country
Greece
Individual Site Status
Recruiting
Facility Name
Research Site
City
Athens
ZIP/Postal Code
155 62
Country
Greece
Individual Site Status
Recruiting
Facility Name
Research Site
City
Peiraias
ZIP/Postal Code
185 47
Country
Greece
Individual Site Status
Recruiting
Facility Name
Research Site
City
Thessaloniki
ZIP/Postal Code
54645
Country
Greece
Individual Site Status
Recruiting
Facility Name
Research Site
City
Thessaloniki
ZIP/Postal Code
57001
Country
Greece
Individual Site Status
Recruiting
Facility Name
Research Site
City
Budapest
ZIP/Postal Code
1121
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Budapest
ZIP/Postal Code
1122
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Gyöngyös - Mátraháza
ZIP/Postal Code
3200
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kaposvár
ZIP/Postal Code
7400
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Pécs
ZIP/Postal Code
7624
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Szekszárd
ZIP/Postal Code
7100
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Szolnok
ZIP/Postal Code
5000
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Törökbálint
ZIP/Postal Code
2045
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Research Site
City
Calicut
ZIP/Postal Code
673601
Country
India
Individual Site Status
Recruiting
Facility Name
Research Site
City
Delhi
ZIP/Postal Code
110029
Country
India
Individual Site Status
Recruiting
Facility Name
Research Site
City
Delhi
ZIP/Postal Code
110085
Country
India
Individual Site Status
Recruiting
Facility Name
Research Site
City
Jaipur
ZIP/Postal Code
302017
Country
India
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kolkata
ZIP/Postal Code
700160
Country
India
Individual Site Status
Recruiting
Facility Name
Research Site
City
Madurai
ZIP/Postal Code
625107
Country
India
Individual Site Status
Recruiting
Facility Name
Research Site
City
New Delhi
ZIP/Postal Code
110063
Country
India
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Puducherry
ZIP/Postal Code
605006
Country
India
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Firenze
ZIP/Postal Code
50134
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lecco
ZIP/Postal Code
23900
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Messina
ZIP/Postal Code
98158
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Napoli
ZIP/Postal Code
80131
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Orbassano
ZIP/Postal Code
10043
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Padova
ZIP/Postal Code
35128
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Parma
ZIP/Postal Code
43126
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Peschiera Del Garda
ZIP/Postal Code
37019
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Rozzano
ZIP/Postal Code
20089
Country
Italy
Individual Site Status
Recruiting
Facility Name
Research Site
City
Bunkyo-ku
ZIP/Postal Code
113-8603
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Chuo-ku
ZIP/Postal Code
104-0045
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hamamatsu-shi
ZIP/Postal Code
431-3192
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hamamatsu-shi
ZIP/Postal Code
432-8580
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hidaka-shi
ZIP/Postal Code
350-1298
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Himeji-shi
ZIP/Postal Code
670-8520
Country
Japan
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Hirosaki-shi
ZIP/Postal Code
036-8563
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hiroshima-shi
ZIP/Postal Code
730-8518
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kumamoto-shi
ZIP/Postal Code
860-8556
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Morioka-shi
ZIP/Postal Code
028-3695
Country
Japan
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Nagoya-shi
ZIP/Postal Code
464-8681
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Nagoya-shi
ZIP/Postal Code
466-8560
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Natori-shi
ZIP/Postal Code
981-1293
Country
Japan
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Okayama-shi
ZIP/Postal Code
700-8558
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Osaka-shi
ZIP/Postal Code
545-8586
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Osakasayama-shi
ZIP/Postal Code
589-8511
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sapporo-shi
ZIP/Postal Code
060-8638
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sunto-gun
ZIP/Postal Code
411-8777
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Wakayama-shi
ZIP/Postal Code
641-8510
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Yokohama-shi
ZIP/Postal Code
221-0855
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Yokohama-shi
ZIP/Postal Code
241-8515
Country
Japan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Busan
ZIP/Postal Code
48108
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Cheongju-si
ZIP/Postal Code
28644
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Jinju-si
ZIP/Postal Code
52727
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Seoul
ZIP/Postal Code
03722
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Seoul
ZIP/Postal Code
05368
Country
Korea, Republic of
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Seoul
ZIP/Postal Code
07061
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Seoul
ZIP/Postal Code
13620
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Suwon-si
ZIP/Postal Code
16499
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Suwon
ZIP/Postal Code
16247
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Research Site
City
Cdmx
ZIP/Postal Code
03810
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Research Site
City
Del. Cuauhtemoc
ZIP/Postal Code
06700
Country
Mexico
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Merida
ZIP/Postal Code
97000
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Research Site
City
Mexico
ZIP/Postal Code
14080
Country
Mexico
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Mexico
ZIP/Postal Code
3100
Country
Mexico
Individual Site Status
Withdrawn
Facility Name
Research Site
City
San Luis Potosí
ZIP/Postal Code
78209
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Research Site
City
Arequipa
ZIP/Postal Code
04002
Country
Peru
Individual Site Status
Recruiting
Facility Name
Research Site
City
Concepción
ZIP/Postal Code
12125
Country
Peru
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Lima
ZIP/Postal Code
15036
Country
Peru
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Lima
ZIP/Postal Code
34
Country
Peru
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Lima
ZIP/Postal Code
LIMA 27
Country
Peru
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Lima
ZIP/Postal Code
LIMA 29
Country
Peru
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Bydgoszcz
ZIP/Postal Code
85-796
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Bystra
ZIP/Postal Code
43-360
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Grudziądz
ZIP/Postal Code
86-300
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Kielce
ZIP/Postal Code
25-734
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Koszalin
ZIP/Postal Code
75-581
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Olsztyn
ZIP/Postal Code
10-357
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Piła
ZIP/Postal Code
64-920
Country
Poland
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Poznań
ZIP/Postal Code
60-569
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Racibórz
ZIP/Postal Code
47-400
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Radom
ZIP/Postal Code
26-600
Country
Poland
Individual Site Status
Not yet recruiting
Facility Name
Research Site
City
Siedlce
ZIP/Postal Code
08-110
Country
Poland
Individual Site Status
Recruiting
Facility Name
Research Site
City
Tomaszów Mazowiecki
ZIP/Postal Code
97-200
Country
Poland
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Wroclaw
ZIP/Postal Code
53-413
Country
Poland
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Girona
ZIP/Postal Code
17007
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Las Palmas de Gran Canaria
ZIP/Postal Code
35016
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lugo
ZIP/Postal Code
27003
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Santander
ZIP/Postal Code
39008
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Valencia
ZIP/Postal Code
46010
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Zaragoza
ZIP/Postal Code
50009
Country
Spain
Individual Site Status
Recruiting
Facility Name
Research Site
City
Gävle
ZIP/Postal Code
801 88
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Research Site
City
Linköping
ZIP/Postal Code
581 85
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Research Site
City
Lund
ZIP/Postal Code
221 85
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Research Site
City
Stockholm
ZIP/Postal Code
17176
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Research Site
City
Uppsala
ZIP/Postal Code
751 85
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Research Site
City
Hsinchu
ZIP/Postal Code
300
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Taichung
ZIP/Postal Code
40705
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Taipei City
ZIP/Postal Code
110
Country
Taiwan
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Taipei City
ZIP/Postal Code
11217
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Taipei
ZIP/Postal Code
235
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Taoyuan City
ZIP/Postal Code
333
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Yung Kang City
ZIP/Postal Code
71044
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Research Site
City
Adana
ZIP/Postal Code
01060
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Research Site
City
Ankara
ZIP/Postal Code
06800
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Research Site
City
Edirne
ZIP/Postal Code
22030
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Research Site
City
Istanbul
ZIP/Postal Code
34098
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Research Site
City
Izmir
ZIP/Postal Code
35110
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Research Site
City
Aberdeen
ZIP/Postal Code
AB25 2ZN
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Cambridge
ZIP/Postal Code
CB2 0QQ
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Cardiff
ZIP/Postal Code
CF14 2TL
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Cheltenham
ZIP/Postal Code
GL53 7AN
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Edinburgh
ZIP/Postal Code
EH4 2XU
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Leicester
ZIP/Postal Code
LE1 5WW
Country
United Kingdom
Individual Site Status
Withdrawn
Facility Name
Research Site
City
London
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
London
ZIP/Postal Code
W6 8RF
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Manchester
ZIP/Postal Code
M20 4BX
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Middlesbrough
ZIP/Postal Code
TS4 3BW
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Newcastle-Upon-Tyne
ZIP/Postal Code
NE7 7DN
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Taunton
ZIP/Postal Code
TA1 5DA
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Research Site
City
Torquay
ZIP/Postal Code
TQ2 7AA
Country
United Kingdom
Individual Site Status
Withdrawn
Facility Name
Research Site
City
Hanoi
ZIP/Postal Code
100000
Country
Vietnam
Individual Site Status
Recruiting
Facility Name
Research Site
City
Ho Chi Minh city
ZIP/Postal Code
700000
Country
Vietnam
Individual Site Status
Recruiting
Facility Name
Research Site
City
Ho Chi Minh
ZIP/Postal Code
700000
Country
Vietnam
Individual Site Status
Recruiting
12. IPD Sharing Statement
Learn more about this trial
Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin for First-Line Treatment of Patients With Advanced NSCLC Without Actionable Genomic Alterations
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