Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection (CROMOPIE)
Colorectal Neoplasms
About this trial
This is an interventional diagnostic trial for Colorectal Neoplasms focused on measuring endoscopic mucosal resection, piecemeal polypectomy scar, colorectal neoplasms, Narrow Band Imaging, chromoendoscopy
Eligibility Criteria
Inclusion Criteria:
- Patients over 18 years old who underwent a colonoscopy for any reason in the last 12 month
- Patients with a basal colonoscopy findings: ≥1 polyp removed in a piecemeal fashion regardless of the size
Exclusion Criteria:
- Diagnosis of a CRC in the basal colonoscopy
- Subjects who neglect to follow-up
- Subjects who do not accept informed consent
- Subjects with high risk of perforation or complications due to sedation, including patients with comorbidities (ASA IV-V)
- Inadequate bowel preparation for colonoscopy (defined by Boston Bowel Preparation Score (BBPS): ≤ 5 total points; or 0-1 points in any of the 3 segments of the colon)
Sites / Locations
- Hospital del Mar
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
WLE-NBI
NBI-WLE
Participants will be evaluated by same endoscopist, tandem colonoscopy. It consists of two revisions of the polypectomy scar using firstly High Definition White Light Endoscopy (WLE) and secondly Narrow Band Imaging. All suspected neoplasia will be classified macroscopically and resected and differentiated from both techniques. The rest of the gut will be inspected following conventional standards.
Participants will be evaluated by same endoscopist, tandem colonoscopy. It consists of two revisions of the polypectomy scar using firstly Narrow Band Imaging and secondly High Definition White Light Endoscopy (WLE). All suspected neoplasia will be classified macroscopically and resected and differentiated from both techniques. The rest of the gut will be inspected following conventional standards.