Back to resultsStudy of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer (ASCENT-04)
Primary Purpose
Triple Negative Breast Cancer, PD-L1 Positive
Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Sacituzumab Govitecan-hziy
Pembrolizumab
Paclitaxel
nab-Paclitaxel
Gemcitabine
Carboplatin
Sponsored by
About this trial
This is an interventional treatment trial for Triple Negative Breast Cancer
Eligibility Criteria
Key Inclusion Criteria:
Individuals with locally advanced, inoperable, or metastatic triple-negative breast cancer (TNBC) who have not received previous systemic therapy for advanced disease and whose tumors are programmed cell death ligand 1 (PD-L1) positive at screening.
- Individuals must have completed treatment for Stage I to III breast cancer, if indicated, and ≥ 6 months must have elapsed between completion of treatment with curative intent and first documented local or distant disease recurrence.
- Individuals presenting with de novo metastatic TNBC are eligible for this study.
- TNBC status and tumor PD-L1 combined positive score (CPS) will be confirmed centrally on a recent or archival tumor specimen.
- Individuals must have measurable disease by computed tomography (CT) or magnetic resonance imaging (MRI) as per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1 criteria as evaluated locally.
- Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1.
- Demonstrates adequate organ function
- Male and female individuals of childbearing potential who engage in heterosexual intercourse must agree to use protocol-specified method(s) of contraception.
- Individuals with HIV must be on antiretroviral therapy (ART) and have a well-controlled HIV infection/disease.
Key Exclusion Criteria:
- Positive serum pregnancy test or women who are lactating.
- Received prior therapy with an agent directed to another stimulatory or coinhibitory T-cell receptor.
- Individuals may not have received systemic anticancer treatment within the previous 6 months or radiation therapy within 2 weeks prior to enrollment.
- Individuals may not be participating in a study with an investigational agent or investigational device within 4 weeks prior to randomization. Individuals participating in observational studies are eligible.
- Have previously received topoisomerase 1 inhibitors or antibody drug conjugates containing a topoisomerase inhibitor.
- Have an active second malignancy.
- Have active serious infection requiring antibiotics.
- Individuals positive for HIV-1 or 2 with a history of Kaposi sarcoma and/or Multicentric Castleman Disease.
- Have active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.
- Has an active autoimmune disease that has required systemic treatment in the past 2 years.
Note: Other protocol defined Inclusion/Exclusion criteria may apply.
Sites / Locations
- Alaska Oncology and HematologyRecruiting
- Arizona Oncology Associates, PC-Hope,1845 W Orange Grove RdRecruiting
- Arizona Oncology Associates, PC-Hope,2070 W. Rudasill Rd.Recruiting
- Arizona Oncology Associates, PC-HopeRecruiting
- Arizona Oncology Associates, PC-Hope,1620 West St. Mary's RoadRecruiting
- Genesis Cancer and Blood InstituteRecruiting
- Genesis Cancer and Blood Institute,1456 Higdon Ferry Road Suite B.Recruiting
- Saint Bernards Medical CenterRecruiting
- Saint Bernards Medical Center,4000 Linwood DriveRecruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer Center,201 S. Buena Vista Street, Suite 200Recruiting
- University of California Irvine Health Chao Family,1640 Newport BlvdRecruiting
- City of HopeRecruiting
- University of California San Diego Moores CancerRecruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer Center,24302 Paseo de Valencia, Suite 200Recruiting
- Cancer and Blood Specialty ClinicRecruiting
- City of Hope,1601 Avocado AveRecruiting
- University of California Irvine Health Chao FamilyRecruiting
- City of Hope,209 Fair Oaks AveRecruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer Center,892 Aerovista Place, Suite 240Recruiting
- Sansum ClinicRecruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer Center,2020 Santa Monica Blvd, Suite 600Recruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer Center,2336 Santa Monica, Suites 302 and 304Recruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer CenterRecruiting
- St. Jude Hospital Yorba dba St. Joseph Heritage HealthcareRecruiting
- Sansum Clinic,2040 Viborg RoadRecruiting
- City of Hope,5215 Torrance BlvdRecruiting
- Torrance Memorial Physician Network - Cancer CareRecruiting
- City of Hope,1100 San Bernardino RdRecruiting
- University of California Los Angeles - Jonsson Comprehensive Cancer Center,1250 La Venta Dr, Suite 100Recruiting
- Rocky Mountain Cancer Centers,1700 South Potomac StreetRecruiting
- Rocky Mountain Cancer CentersRecruiting
- Rocky Mountain Cancer Centers,2312 N. Nevada AvenueRecruiting
- Rocky Mountain Cancer Centers,6031 E. Woodman Rd.Recruiting
- Rocky Mountain Cancer Centers,4700 E. Hale ParkwayRecruiting
- Rocky Mountain Cancer Centers,11750 West 2nd PlaceRecruiting
- Rocky Mountain Cancer Centers,22 West Dry Creek CircleRecruiting
- Rocky Mountain Cancer Centers,10107 Ridge Gate ParkwayRecruiting
- Rocky Mountain Cancer Centers,2030 Mountain View Ave Ste 210Recruiting
- Rocky Mountain Cancer Centers,3676 Parker BlvdRecruiting
- Rocky Mountain Cancer Centers,525 W. 15th StreetRecruiting
- Rocky Mountain Cancer Centers,8820 Huron StreetRecruiting
- Eastern Connecticut Hematology and Oncology AssociatesRecruiting
- Advent Health Medical GroupRecruiting
- SCRI - Florida Cancer Specialists - North Region R,106 Boston AveRecruiting
- University of Miami - Sylvester Comprehensive Cancer Center,2801 NE 213th StRecruiting
- Florida Cancer Specialists,9776 Bonita Beach Road Southeast Suite 201 ARecruiting
- Florida Cancer Specialists,3630 Manatee Avenue WestRecruiting
- Florida Cancer Specialists,5985 Silver Falls RunRecruiting
- SCRI - Florida Cancer Specialists - North Region R,403 S. Kings Ave.Recruiting
- Florida Cancer Specialists,1030 Commerce Creek BlvdRecruiting
- SCRI - Florida Cancer Specialists - North Region R,3280 McMullen Booth RoadRecruiting
- University of Miami - Sylvester Comprehensive Cancer Center,5555 Ponce De Leon BlvdRecruiting
- SCRI - Florida Cancer Specialists - West Palm Beach,224 Memorial Medical Parkway, Suite 300Recruiting
- University of Miami - Sylvester Comprehensive Cancer Center,1192 East Newport Center DriveRecruiting
- Florida Cancer SpecialistsRecruiting
- Florida Cancer Specialists,8981 Colonial Center DriveRecruiting
- Florida Cancer Specialists,8260 Gladiolus DrRecruiting
- SCRI - Florida Cancer Specialists - North Region R,6420 W. Newberry RoadRecruiting
- University of Miami - Sylvester Comprehensive Cancer Center,3850 Hollywood BlvdRecruiting
- SCRI - Florida Cancer Specialists - North Region R,100 Highland AvenueRecruiting
- SCRI - Florida Cancer Specialists - North Region R,521 North Lecanto HighwayRecruiting
- University of Miami - Sylvester Comprehensive Cancer Center,1400 NW 12th AveRecruiting
- University of Miami - Sylvester Comprehensive Cancer CenterRecruiting
- University of Miami - Sylvester Comprehensive Cancer Center,8932 S.W. 97 AveRecruiting
- Florida Cancer Specialists,1100 Goodlette RoadRecruiting
- SCRI - Florida Cancer Specialists - North Region R,4945 SW 49th PlaceRecruiting
- SCRI - Florida Cancer Specialists - North Region R,765 Image WayRecruiting
- Advent Health Medical Group,2501 North Orange AveRecruiting
- SCRI - Florida Cancer Specialists - North Region R,70 W. Gore StreetRecruiting
- University of Miami - Sylvester Comprehensive Cancer Center,8100 SW 10 StreetRecruiting
- Florida Cancer Specialists,22395 Edgewater DriveRecruiting
- SCRI - Florida Cancer Specialists - North Region R,1201 Fifth Avenue NorthRecruiting
- SCRI - Florida Cancer Specialists - North Region RRecruiting
- Florida Cancer Specialists,600 North Cattlemen RoadRecruiting
- Florida Cancer Specialists,1970 Golf StreetRecruiting
- SCRI - Florida Cancer Specialists - North Region R,7154 Medical Center DriveRecruiting
- SCRI - Florida Cancer Specialists - West Palm Beach,301 SE Ocean Blvd, Suite 102Recruiting
- SCRI - Florida Cancer Specialists - North Region R,3402 West Dr. Martin Luther King Jr. BoulevardRecruiting
- SCRI - Florida Cancer Specialists - North Region R,4100 Waterman WayRecruiting
- SCRI - Florida Cancer Specialists - North Region R,1400 US Highway 441 NRecruiting
- SCRI - Florida Cancer Specialists - North Region R,9320 State Road 54Recruiting
- Florida Cancer Specialists,836 Sunset Lake BlvdRecruiting
- SCRI - Florida Cancer Specialists - West Palm Beach,3730 7th Terrace, Suite 101Recruiting
- SCRI - Florida Cancer Specialists - West Palm Beach,1037 S. State Road 7, Bldg B, Suite 303Recruiting
- SCRI - Florida Cancer Specialists - West Palm BeachRecruiting
- SCRI - Florida Cancer Specialists - North Region R,460 N Orlando AveRecruiting
- Northside Hospital,125 King AvenueRecruiting
- Piedmont Cancer Institute - Atlanta,1267 Hwy 54WRecruiting
- Winship Cancer Institute of Emory University,550 Peachtree St NERecruiting
- Piedmont Cancer Institute - AtlantaRecruiting
- Winship Cancer Institute of Emory UniversityRecruiting
- Northside Hospital,5670 Peachtree Dunwoody Rd.Recruiting
- Northside HospitalRecruiting
- Winship Cancer Institute of Emory University,5665 Peachtree Dunwoody RoadRecruiting
- Northside Hospital,308 Deep South Farm Rd, Suite 200Recruiting
- Northside Hospital,228 Riverstone Dr.Recruiting
- Northside Hospital,1505 Northside Blvd, Suite 4600Recruiting
- Northside Hospital,3855 Pleasant Hill Rd., Suite 480Recruiting
- Northside Hospital,308 Coliseum Dr.Recruiting
- Piedmont Cancer Institute - Atlanta,775 Poplar RoadRecruiting
- Piedmont Cancer Institute - Atlanta,1240 Eagles Landing PkwyRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityRecruiting
- University of Illinois Hospital and Health Sciences System (Outpatient Cancer Center)Recruiting
- Orchard Healthcare Research Inc,2845 North Sheridan Road, 1st FloorRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1 Kish Hospital DriveRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,10 Health Services DriveRecruiting
- Orchard Healthcare Research Inc,800 Austin Street, Suite 360, East TowerRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,300 Randall RoadRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,304 Randall RoadRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1000 N. Westmoreland RoadRecruiting
- Orchard Healthcare Research IncRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4405 Weaver ParkwayRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4455 Weaver ParkwayRecruiting
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University,25 N Winfield RoadRecruiting
- Regulatory Management Only: TRIO-US Central AdministrationRecruiting
- The University of Kansas Cancer Center,2000 Olathe BlvdRecruiting
- The University of Kansas Cancer Center,12200 W. 110th StreetRecruiting
- The University of Kansas Cancer Center,10710 Nall AvenueRecruiting
- The University of Kansas Cancer Center,10730 Nall AvenueRecruiting
- The University of Kansas Cancer CenterRecruiting
- Norton Cancer Institute - Saint Matthews,234 E. Gray StrretRecruiting
- Norton Cancer Institute - Saint Matthews,676 S. Floyd StreetRecruiting
- Norton Cancer Institute - Saint MatthewsRecruiting
- Norton Cancer Institute - Saint Matthews,4955 Norton Healthcare BlvdRecruiting
- Hematology Oncology Clinic - Baton RougeRecruiting
- Hematology Oncology Clinic - Baton Rouge,1673 E Mount Please DriveRecruiting
- Cancer Institute Ascension Saint AgnesRecruiting
- Beth Israel Deaconess Medical CenterRecruiting
- Dana-Farber Cancer InstituteRecruiting
- Massachusetts General HospitalRecruiting
- Massachusetts General Hospital,102 Endicott StreetRecruiting
- Massachusetts General Hospital,2014 Washington StRecruiting
- Ascension St. John HospitalRecruiting
- Ascension Providence Hospital Southfield Cancer CenterRecruiting
- Mayo ClinicRecruiting
- The West Clinic, PLLC dba West Cancer Center,7668 Airways BlvdRecruiting
- The University of Kansas Cancer Center,2750 Clay Edwards DriveRecruiting
- The University of Kansas Cancer Center,8700 North Green Hills RoadRecruiting
- The University of Kansas Cancer Center,4881 N.E. Goodview CircleRecruiting
- Nebraska Cancer Specialists,2730 W. Faidley AveRecruiting
- Nebraska Cancer Specialists,8303 Dodge StreetRecruiting
- Nebraska Cancer SpecialistsRecruiting
- Nebraska Cancer Specialists,611 Fenwick DrRecruiting
- Comprehensive Cancer Centers of Nevada - Central V,10001 S. Eastern Avenue, Suite 108Recruiting
- Comprehensive Cancer Centers of Nevada - Central V,2460 W. Horizon Ridge ParkwayRecruiting
- Comprehensive Cancer Centers of Nevada - Central V,1501 Wigwam Parkway, Suite 1300Recruiting
- Comprehensive Cancer Centers of Nevada - Central V,653 North Town Center Drive, Suite 402Recruiting
- Comprehensive Cancer Centers of Nevada - Central V,9280 W. Sunset Road Suite 100Recruiting
- Comprehensive Cancer Centers of Nevada - Central V,7445 Peak DriveRecruiting
- Comprehensive Cancer Centers of Nevada - Central VRecruiting
- Summit Medical Group,1 Diamond Hill RoadRecruiting
- Regional Cancer Care Associates - East BrunswickRecruiting
- Summit Medical GroupRecruiting
- John Theurer Cancer CenterRecruiting
- Rutgers Cancer Institute of New Jersey,2575 Klockner RoadRecruiting
- Rutgers Cancer Institute of New Jersey,414 Grand StreetRecruiting
- Rutgers Cancer Institute of New Jersey,600 River AvenueRecruiting
- Rutgers Cancer Institute of New Jersey,94 Old Short Hills RoadRecruiting
- Rutgers Cancer Institute of New Jersey,300 Second AveRecruiting
- Regional Cancer Care Associates - East Brunswick,9 Centre DriveRecruiting
- Regional Cancer Care Associates - East Brunswick,34-36 Progress StreetRecruiting
- Rutgers Cancer Institute of New JerseyRecruiting
- Rutgers Cancer Institute of New Jersey,150 Bergen St.Recruiting
- Rutgers Cancer Institute of New Jersey,201 Lyons AvenueRecruiting
- Regional Cancer Care Associates - East Brunswick,75 Veronica AvenueRecruiting
- Rutgers Cancer Institute of New Jersey,110 Rehill AveRecruiting
- Rutgers Cancer Institute of New Jersey,99 Highway 37 WestRecruiting
- Rutgers Cancer Institute of New Jersey,100 State Route 36Recruiting
- New York Cancer & Blood Specialists - Port Jeffers,72 East Main St.Recruiting
- New York Cancer & Blood Specialists - Port Jeffers,12 East 86th St, Suite 4Recruiting
- Montefiore Medical Center - Montefiore Medical ParkRecruiting
- New York Cancer & Blood Specialists - Port Jeffers,2330 Eastchester Road, Suite 360Recruiting
- Perlmutter Cancer Center - Manhattan - 34th Street,259 First StreetRecruiting
- New York Cancer & Blood Specialists - Port Jeffers,1 Delaware Dr.Recruiting
- Perlmutter Cancer Center - Manhattan - 34th StreetRecruiting
- NYP/Columbia Univeresity Medical Center/Herbert Irving Comprehensive Cancer CenterRecruiting
- New York Cancer & Blood Specialists - Port Jeffers,365 East Main St.Recruiting
- New York Cancer & Blood Specialists - Port Jeffers,49 Rte. 347, Newconset HwyRecruiting
- New York Cancer & Blood Specialists - Port JeffersRecruiting
- New York Cancer & Blood Specialists - Port Jeffers,1500 Rte, 112, Building 4Recruiting
- New York Cancer & Blood Specialists - Port Jeffers,750 Old County Rd. Suite 4Recruiting
- The Ohio State University Wexner Medical Center Clinical LaboratoriesRecruiting
- Zangmeister Cancer CenterRecruiting
- Northwest Cancer Specialists, PC,5050 NE Hoyt St.Recruiting
- Northwest Cancer Specialists, PC,265 N. BroadwayRecruiting
- Northwest Cancer Specialists, PCRecruiting
- Magee-Womens Hospital of UPMC,200 Oxford DriveRecruiting
- Magee-Womens Hospital of UPMC,3 St. Francis WayRecruiting
- Magee-Womens Hospital of UPMC,2500 West 12th StreetRecruiting
- Magee-Womens Hospital of UPMC,201 State Street, 6 MainRecruiting
- Magee-Womens Hospital of UPMC,200 Village DriveRecruiting
- Magee-Womens Hospital of UPMC,4300 Londonberry RoadRecruiting
- Magee-Womens Hospital of UPMC,400 Oxford DriveRecruiting
- University of Pennsylvania Abramson Cancer CenterRecruiting
- Magee-Womens Hospital of UPMCRecruiting
- Magee-Womens Hospital of UPMC,5115 Centre AvenueRecruiting
- Magee-Womens Hospital of UPMC,9100 Babcock BoulevardRecruiting
- Magee-Womens Hospital of UPMC,100 Fairfield DrRecruiting
- Magee-Womens Hospital of UPMC,470 Johnson RoadRecruiting
- Magee-Womens Hospital of UPMC,1703 Innovation DriveRecruiting
- Rhode Island HospitalRecruiting
- Rhode Island Hospital,164 Summit Ave, Fain 275ARecruiting
- Tennessee Oncology, PLLC,103 Natchez Park DriveRecruiting
- Tennessee Oncology, PLLC,4488 Carothers ParkwayRecruiting
- Tennessee Oncology, PLLC,225 Big Station Camp BlvdRecruiting
- The West Clinic, PLLC dba West Cancer CenterRecruiting
- Tennessee Oncology, PLLC,353 New Shackle Island RoadRecruiting
- Tennessee Oncology, PLLC,5653 First Blvd.Recruiting
- Tennessee Oncology, PLLC,103 Physicians WayRecruiting
- Tennessee Oncology, PLLC,1840 Medical Center ParkwayRecruiting
- Tennessee Oncology, PLLC,2004 Hayes StreetRecruiting
- Tennessee Oncology, PLLCRecruiting
- Tennessee Oncology, PLLC,4220 Harding RdRecruiting
- Tennessee Oncology, PLLC,3443 Dickerson RoadRecruiting
- Tennessee Oncology, PLLC,397 Wallace RoadRecruiting
- Tennessee Oncology, PLLC,120 Frank Martin RoadRecruiting
- Tennessee Oncology, PLLC,300 Stonecrest BlvdRecruiting
- The Center for Cancer and Blood Disorders - Magnolia,515 W. Mayfield Rd.Recruiting
- Texas Oncology-Austin,901 West 38th StreetRecruiting
- Texas Oncology-AustinRecruiting
- Texas Oncology-Austin,4101 James Casey, Suite 100Recruiting
- The Center for Cancer and Blood Disorders - Magnolia,11805 South FreewayRecruiting
- Texas Oncology-Baylor Charles A. Sammons Cancer CenterRecruiting
- Texas Oncology-DenisonRecruiting
- The Center for Cancer and Blood Disorders - MagnoliaRecruiting
- Oncology Consultants,1631 North Loop WestRecruiting
- Oncology Consultants,925 GessnerRecruiting
- Oncology ConsultantsRecruiting
- University of Texas MD Anderson Cancer Center,1155 Pressler StRecruiting
- University of Texas MD Anderson Cancer CenterRecruiting
- Mays Cancer CenterRecruiting
- The Center for Cancer and Blood Disorders - Magnolia,920 Santa Fe DriveRecruiting
- Huntsman Cancer Institute, University of Utah,165 North University AvenueRecruiting
- Huntsman Cancer Institute, University of Utah,1280 E. Stringham AvenueRecruiting
- Huntsman Cancer Institute, University of UtahRecruiting
- Huntsman Cancer Institute, University of Utah,5126 West Daybreak ParkwayRecruiting
- Virginia Oncology Associates,744 N. Battlefield BlvdRecruiting
- Virginia Cancer Institute,7501 Right Flank RoadRecruiting
- Virginia Oncology Associates,1051 Loftis Blvd Suite 100Recruiting
- Virginia Oncology AssociatesRecruiting
- Virginia Cancer Institute,210 Medical Park BoulevardRecruiting
- Virginia Cancer Institute,1401 Johnston-Willis DriveRecruiting
- Virginia Cancer InstituteRecruiting
- Virginia Oncology Associates,1950 Glenn Mitchell DriveRecruiting
- Northwest Cancer Specialists, PC,210 SE 136th AvenueRecruiting
- Hospital Británico de Buenos AiresRecruiting
- Instituto de Oncología Ángel H. RoffoRecruiting
- Fundacion CORI para la Investigacioy y Prevención del CancerRecruiting
- Instituto de Oncologia de RosarioRecruiting
- CAIPO Centro Para La Atención Integral Del PacientRecruiting
- Clinica ViedmaRecruiting
- Border Medical OncologyRecruiting
- Saint George Hospital - AustraliaRecruiting
- Mater Hospital - North SydneyRecruiting
- GenesisCare - North ShoreRecruiting
- Mater Misericordiae Limited and Mater Research LimitedRecruiting
- Princess Alexandra HospitalRecruiting
- Cancer Research SA (CRSA)Recruiting
- Icon Cancer Centre HobartRecruiting
- Monash Medical CentreRecruiting
- Austin HospitalRecruiting
- Peter MacCallum Cancer CentreRecruiting
- Breast Cancer Research Center - Western AustraliaRecruiting
- Medizinische Universität InnsbruckRecruiting
- Ordensklinikum Linz GmbH Barmherzige SchwesternRecruiting
- Landeskrankenhaus SalzburgRecruiting
- Universitätsklinikum Sankt PöltenRecruiting
- Medizinische Universität WienRecruiting
- Institut Jules BordetRecruiting
- Algemeen Ziekenhuis KlinaRecruiting
- Cliniques Universitaires Saint-LucRecruiting
- Universitair Ziekenhuis BrusselRecruiting
- Grand Hopital de Charleroi - Notre DameRecruiting
- Universitair Ziekenhuis GentRecruiting
- UZ LeuvenRecruiting
- Centre Hospitalier Universitaire Université CatholRecruiting
- Hospital Araújo Jorge - Associacao de Combate ao Cancer em Goias - ACCGRecruiting
- Centro de Pesquisa Clinica Em Oncologia - ONCOSITERecruiting
- Hospital de Clinicas de Porto Alegre - HCPARecruiting
- Centro de Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho - Hospital Amarval CarvalhoRecruiting
- Associacao Hosptialar Moinos de Vento - Hospital Moinhos de VentoRecruiting
- Hospital de Clínicas de Porto AlegreRecruiting
- Hospital Sao Lucas da PUCRSRecruiting
- Instituto Nacional de Câncer - BrazilRecruiting
- Núcleo de Oncologia da BahiaRecruiting
- CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Centro Universitário FMABCRecruiting
- Real e Benemerita Associacao Portuguesa de Beneficencia - Hospital Beneficencia Portuguesa (BP) - Unidade PaulistaRecruiting
- Clinica de Pesquisas e Centro de Estudos em OncoloRecruiting
- Fundação Pio XII - Hospital de Câncer de BarretosRecruiting
- Nucleo de Pesquisa Clinica da Rede Sao CamiloRecruiting
- Tom Baker Cancer CentreRecruiting
- Cross Cancer InstituteRecruiting
- QEII Health Sciences CentreRecruiting
- Grand River Regional Cancer Centre at Grand River HospitalRecruiting
- London Health Sciences CentreRecruiting
- McGill University Health CentreRecruiting
- Jewish General HospitalRecruiting
- Princess Margaret Cancer Centre - University Health NetworkRecruiting
- Ottawa Hospital - General CampusRecruiting
- Sunnybrook Research InstituteRecruiting
- Mount Sinai HospitalRecruiting
- British Columbia Cancer - VancouverRecruiting
- Oncovida - SantiagoRecruiting
- Clínica IRAMRecruiting
- Centro de Cancer Pontificia Universidad CatolicaRecruiting
- Clínica AlemanaRecruiting
- James Lind Centro de Investigacion del CancerRecruiting
- Masarykuv Onkologicky Ustav, Klinika Komplexni Onkologicke PeceRecruiting
- Fakultní Thomayerova nemocniceRecruiting
- Fakultní Nemocnice Hradec KrálovéRecruiting
- Fakultni nemocnice Olomouc, Onkologicka klinikaRecruiting
- Vseobecna Fakultni Nemocnice v Praze, Onkologicka klinikaRecruiting
- Fakultní Nemocnice Královské Vinohrady, Radioterapeuticka a onkologicka klinikaRecruiting
- Sainte Catherine Institut du Cancer Avignon ProvenceRecruiting
- Centre Hospitalier Régional et Universitaire de BeRecruiting
- Polyclinique Bordeaux Nord AquitaineRecruiting
- Hôpital Morvan, Institut de cancérologieRecruiting
- Centre de Lutte contre le Cancer - François BaclesRecruiting
- Centre Jean PerrinRecruiting
- Centre Leon BerardRecruiting
- Institut Paoli-CalmettesRecruiting
- Institut Régional du Cancer de MontpellierRecruiting
- Centre de Cancérologie du Grand MontpellierRecruiting
- Hôpital Privé du ConfluentRecruiting
- Hospices Civils de Lyon, Hôpital Lyon SudRecruiting
- Centre Armoricain de Radiothérapie, dImagerie MédRecruiting
- Centre Eugène MarquisRecruiting
- Institut Claudius Regaud - IUCT-ORecruiting
- Institut Gustave RoussyRecruiting
- Helios Klinikum Berlin-BuchRecruiting
- : Gynakologisches Zentrum Bonn, Schwerpunkt Gyn. Onkologie,Recruiting
- Marienhospital BottropRecruiting
- Universitätsklinikum Erlangen, Frauen klinikRecruiting
- Kliniken Essen-Mitte - Evangelische Huyssens-StiftRecruiting
- Praxis für interdisziplinäre Onkologie & HämatologRecruiting
- : Universitätsklinikum Hamburg-EppendorfRecruiting
- Facharztzentrum EppendorfRecruiting
- Nationales Centrum für TumorerkrankungenRecruiting
- Klinik Frauenheilkunde, Uniklinik ClO, StudienzentraleRecruiting
- Universitätsklinikum Schleswig-Holstein Institut fur Klinische ChermieRecruiting
- Universitatsklinikum Mannheim GmBH, FrauenklinikRecruiting
- Universitätsklinikum Münster, Bereich Senologie an der klinik fur Frauenheilkunde und GerburtschilfeRecruiting
- EV. Krankenhaus Bethesda - Johanniter GmbH, Station 1 Brustzentrum NiederrheinRecruiting
- Rotkreuzklinikum Munchen FrauenklinikRecruiting
- Klinik und Poliklinik für FrauenheilkundeRecruiting
- Universitatsklinikum TubingenRecruiting
- St. Josefs-Hospital Wiesbaden GmbH, Gynakologie und GeburtshilfeRecruiting
- Department of Medicine, Queen Mary HospitalRecruiting
- Hong Kong Sanatorium and HospitalRecruiting
- Tuen Mun HospitalRecruiting
- Prince of Wales Hospital - Hong KongRecruiting
- Orszagos Onkologiai IntezetRecruiting
- Uzsoki Utcai KórházRecruiting
- Debreceni Egyetem Klinikai KözpontRecruiting
- Petz Aladár Egyetemi Oktató Kórház - Gy?rRecruiting
- Soroka Medical CenterRecruiting
- Rambam Health Care CampusRecruiting
- Shaare Zedek Medical CenterRecruiting
- Hadassah - Hebrew University Medical CenterRecruiting
- Meir Medical CenterRecruiting
- Rabin Medical CenterRecruiting
- Kaplan Medical CenterRecruiting
- Sheba Medical Center Hospital - Tel HashomerRecruiting
- Tel Aviv Sourasky Medical CenterRecruiting
- IRCCS Istituto Tumori "Giovanni Paolo II"Recruiting
- SSD Oncologia Medica Addarii-Zamagni, IRCSS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'OrsolaRecruiting
- UO Oncologia, ASST degli Spedali Civili di BresciaRecruiting
- IRCCS Ospedale Policlinico San MartinoRecruiting
- S.C. Oncologia medica, ASST di LeccoRecruiting
- Presidio Ospedaliero di LuccaRecruiting
- Ospedale San RaffaeleRecruiting
- Fondazione IRCCS - Istituto Nazionale dei TumoriRecruiting
- Centro Ricerca Fase I, Fondazione IRCSS San Gerado dei TintoriRecruiting
- Oncologia Medica Senologica Sperimentale - Istituto Nazionale Tumori IRCCS Fondazione G. PascaleRecruiting
- AOU Maggiore della CaritaRecruiting
- Istituto Oncologico Veneto - IRCCSRecruiting
- S.O.C Oncologia Medica, Nuovo Ospedale di Prato Santo StefanoRecruiting
- Policlinico di RomaRecruiting
- Fondazione Policlinico Universitario Agostino GemeRecruiting
- Azienda Ospedaliera Universitaria Senese - LospedRecruiting
- Aichi Cancer Center HospitalRecruiting
- Tohoku University HospitalRecruiting
- Juntendo University HospitalRecruiting
- Chiba Cancer CenterRecruiting
- Osaka Prefectural Hospital Organization Osaka International Cancer InstituteRecruiting
- NHO Shikoku Cancer CenterRecruiting
- Fukushima Medical University HospitalRecruiting
- Saitama Cancer CenterRecruiting
- Hakuaikai Sagara HospitalRecruiting
- National Cancer Center Hospital EastRecruiting
- The Cancer Institute Hospital of JFCRRecruiting
- Kumamoto University HospitalRecruiting
- Kure Medical Center And Chugoku Cancer CenterRecruiting
- Mie University HospitalRecruiting
- Nagoya University HospitalRecruiting
- Nagoya City University HospitalRecruiting
- Hiroshima City Hiroshima Citizens HospitalRecruiting
- NIigata Cancer Center HospitalRecruiting
- Okayama University HospitalRecruiting
- Gunma Prefectural Cancer CenterRecruiting
- Kyoto University HospitalRecruiting
- Hokkaido Cancer CenterRecruiting
- Shizuoka General HospitalRecruiting
- Shizuoka Cancer CenterRecruiting
- Osaka University HospitalRecruiting
- Showa University HospitalRecruiting
- Kanagawa Cancer CenterRecruiting
- National Cancer Center - KoreaRecruiting
- Seoul National University Bundang HospitalRecruiting
- Severance HospitalRecruiting
- Asan Medical CenterRecruiting
- Samsung Medical CenterRecruiting
- Korea University Anam HospitalRecruiting
- Seoul National University HospitalRecruiting
- The Catholic University of Korea, Seoul St. Mary's HospitalRecruiting
- Icaro Investigaciones en Medicina S.A. de C.V.Recruiting
- Cryptex Investigación ClínicaRecruiting
- Centro para el Desarrollo de la MedicinaRecruiting
- Panamerican Clinical Research Mexico - GuadalajaraRecruiting
- Medical Care and Research S.A. de C.VRecruiting
- Avix Investigacion Clinica S.C.Recruiting
- Fucam A.C.Recruiting
- Oncológico PotosinoRecruiting
- FAICIC Clínical ResearchRecruiting
- iBiomed - Investigacion Biomedica para el DesarrolRecruiting
- Amphia Ziekenhuis - Breda LangendijkRecruiting
- Universitair Medisch Centrum GroningenRecruiting
- Medisch Centrum LeeuwardenRecruiting
- Erasmus Medisch CentrumRecruiting
- Narodowy Instytut Onkologii im. Marii SklodowskiejRecruiting
- SP ZOZ Opolskie Centrum Onkologii im. prof. Tadeusza KoszarowskiegoRecruiting
- Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-CurieRecruiting
- Mazowiecki Szpital Wojewódzki im. w. Jana Pawa II wRecruiting
- Wojskowy Instytut MedycznyRecruiting
- Narodowy Instytut Onkologii im.Marii Marii SklodowskiejsRecruiting
- Ponce Medical School Foundation Inc.Recruiting
- Clinical Research Puerto RicoRecruiting
- Hopelands Cancer CentreRecruiting
- The Medical Oncology Centre of RosebankRecruiting
- University of PretoriaRecruiting
- Hospital Teresa Herrera - Materno InfantilRecruiting
- Hospital Universitari DexeusRecruiting
- Hospital Clinic BarcelonaRecruiting
- Hospital de la Santa Creu i Sant PauRecruiting
- Hospital Universitari Vall d'HebrónRecruiting
- Hospital Universitario de BasurtoRecruiting
- Hospital Universitari Arnau de VilanovaRecruiting
- Hospital General Universitario Gregorio MarañónRecruiting
- MD Anderson Cancer Centre MadridRecruiting
- Hospital Universitario Fundación Jiménez DíazRecruiting
- Hospital Universitario Virgen de la VictoriaRecruiting
- Hospital General Universitario Morales MeseguerRecruiting
- Hospital Unviersitario Virgen del RocioRecruiting
- Hospital Universitario Virgen MacarenaRecruiting
- Hospital Universitario de CanariasRecruiting
- Hospital Clínico Universitario de ValenciaRecruiting
- Kantonsspital BadenRecruiting
- Kantonsspital Baselland - Standort LiestalRecruiting
- Kantonsspital Sankt GallenRecruiting
- Kantonsspital WinterthurRecruiting
- Brust-Zentrum ZurichRecruiting
- Changhua Christian HospitalRecruiting
- Kaohsiung Medical University Chung-Ho Memorial HospitalRecruiting
- Taipei Medical University-Shuang Ho HospitalRecruiting
- National Cheng Kung University HospitalRecruiting
- Taipei Veterans General HospitalRecruiting
- National Taiwan University HospitalRecruiting
- Linkou Chang Gung Memorial HospitalRecruiting
- Baskent Uni. Dr Turgut Noyan Uyg. ve Aras. MerkeziRecruiting
- Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve ARecruiting
- Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalRecruiting
- Memorial Ankara HastanesiRecruiting
- Hacettepe Üniversitesi HastanesiRecruiting
- Trakya Universitesi Tip Fakultesi HastanesiRecruiting
- Istanbul Il Saglik Mudurlugu Goztepe Prof. Dr. SulRecruiting
- Medipol Mega Universite HastanesiRecruiting
- Medicana International Izmir HastanesiRecruiting
- Acibadem Maslak HastanesiRecruiting
- NHS LothianRecruiting
- Clinical Trials Unit Lvl 0 Cancer Research UK Beatson InstituteRecruiting
- Leeds Teaching Hospitals NHS TrustRecruiting
- : Barts Health NHS Trust, St HospitalRecruiting
- Guy's and Saint Thomas' NHS Foundation TrustRecruiting
- University College London HospitalsRecruiting
- Nottingham University Hospitals NHS TrustRecruiting
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
Sacituzumab Govitecan-hziy (SG) + Pembrolizumab
Pembrolizumab + Treatment of Physician's Choice (TPC)
Arm Description
Participants will receive SG 10 mg/kg on Days 1 and 8 of 21-day cycles and pembrolizumab 200 mg on Day 1 of 21-day cycles Pembrolizumab will be administered for a maximum of 35 cycles.
Participants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens: Paclitaxel 90 mg/m^2 on Days 1, 8, and 15 of 28-day cycles nab-Paclitaxel 100 mg/m^2 on Days 1, 8, and 15 of 28-day cycles Gemcitabine 1000 mg/m^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Outcomes
Primary Outcome Measures
Progression-free Survival (PFS) as Assessed by Blinded Independent Central Review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1
PFS is defined as the time from the date of randomization until the date of objective progressive disease (PD) or death (whichever comes first).
Secondary Outcome Measures
Overall Survival (OS)
OS is defined as the time from the date of randomization until death due to any cause.
Objective Response Rate (ORR) as Assessed by BICR per RECIST Version 1.1
ORR is defined as the proportion of participants who achieve complete response (CR) or partial response (PR) that is confirmed at least 4 weeks after initial documentation of response.
Duration of Response (DOR) as Assessed by BICR per RECIST Version 1.1
DOR is defined as the time from the first documentation of CR or PR to the earlier of the first documentation of objective PD or death from any cause (whichever comes first).
Time to Response (TTR) as Assessed by BICR per RECIST Version 1.1
TTR is defined as the time from the date of randomization until the first documentation of CR or PR.
Percentage of Participants Experiencing Treatment-emergent Adverse Events (TEAEs)
Percentage of Participants Experiencing Clinical Laboratory Abnormalities
Time to Deterioration (TTD) in Global Health Status/Quality of Life (QoL) Scale as Measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core Questionnaire, Version 3.0 (EORTC QLQ-C30)
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (i.e. a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (i.e. a worse state of the participant).
TTD of Pain Score as Measured by EORTC QLQ-C30
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (i.e. a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (i.e. a worse state of the participant).
TTD of Fatigue Score as Measured by EORTC QLQ-C30
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).
TTD of Physical Functioning Domain Score as Measured by EORTC QLQ-C30
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).
TTD of Role Functioning Score as Measured by EORTC QLQ-C30
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).
Full Information
NCT ID
NCT05382286
First Posted
May 16, 2022
Last Updated
October 17, 2023
Sponsor
Gilead Sciences
Collaborators
Merck Sharp & Dohme LLC
1. Study Identification
Unique Protocol Identification Number
NCT05382286
Brief Title
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
Acronym
ASCENT-04
Official Title
A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer, Whose Tumors Express PD-L1
Study Type
Interventional
2. Study Status
Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
July 25, 2022 (Actual)
Primary Completion Date
February 2027 (Anticipated)
Study Completion Date
February 2027 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Gilead Sciences
Collaborators
Merck Sharp & Dohme LLC
4. Oversight
Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versus treatment of physician's choice (TPC) and pembrolizumab in participants with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors express programmed cell death ligand 1 (PD-L1).
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Triple Negative Breast Cancer, PD-L1 Positive
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
440 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Sacituzumab Govitecan-hziy (SG) + Pembrolizumab
Arm Type
Experimental
Arm Description
Participants will receive SG 10 mg/kg on Days 1 and 8 of 21-day cycles and pembrolizumab 200 mg on Day 1 of 21-day cycles
Pembrolizumab will be administered for a maximum of 35 cycles.
Arm Title
Pembrolizumab + Treatment of Physician's Choice (TPC)
Arm Type
Active Comparator
Arm Description
Participants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens:
Paclitaxel 90 mg/m^2 on Days 1, 8, and 15 of 28-day cycles
nab-Paclitaxel 100 mg/m^2 on Days 1, 8, and 15 of 28-day cycles
Gemcitabine 1000 mg/m^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Intervention Type
Drug
Intervention Name(s)
Sacituzumab Govitecan-hziy
Other Intervention Name(s)
IMMU-132, Trodelvy™, GS-0132
Intervention Description
Administered intravenously
Intervention Type
Drug
Intervention Name(s)
Pembrolizumab
Other Intervention Name(s)
Keytruda®
Intervention Description
Administered intravenously
Intervention Type
Drug
Intervention Name(s)
Paclitaxel
Other Intervention Name(s)
Taxol®
Intervention Description
Administered intravenously
Intervention Type
Drug
Intervention Name(s)
nab-Paclitaxel
Other Intervention Name(s)
Abraxane®
Intervention Description
Administered intravenously
Intervention Type
Drug
Intervention Name(s)
Gemcitabine
Other Intervention Name(s)
Gemzar
Intervention Description
Administered intravenously
Intervention Type
Drug
Intervention Name(s)
Carboplatin
Intervention Description
Administered intravenously
Primary Outcome Measure Information:
Title
Progression-free Survival (PFS) as Assessed by Blinded Independent Central Review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1
Description
PFS is defined as the time from the date of randomization until the date of objective progressive disease (PD) or death (whichever comes first).
Time Frame
Randomization up to approximately 33 months
Secondary Outcome Measure Information:
Title
Overall Survival (OS)
Description
OS is defined as the time from the date of randomization until death due to any cause.
Time Frame
Randomization up to approximately 53 months
Title
Objective Response Rate (ORR) as Assessed by BICR per RECIST Version 1.1
Description
ORR is defined as the proportion of participants who achieve complete response (CR) or partial response (PR) that is confirmed at least 4 weeks after initial documentation of response.
Time Frame
Randomization up to approximately 53 months
Title
Duration of Response (DOR) as Assessed by BICR per RECIST Version 1.1
Description
DOR is defined as the time from the first documentation of CR or PR to the earlier of the first documentation of objective PD or death from any cause (whichever comes first).
Time Frame
Randomization up to approximately 53 months
Title
Time to Response (TTR) as Assessed by BICR per RECIST Version 1.1
Description
TTR is defined as the time from the date of randomization until the first documentation of CR or PR.
Time Frame
Randomization up to approximately 53 months
Title
Percentage of Participants Experiencing Treatment-emergent Adverse Events (TEAEs)
Time Frame
First dose date up to 53 months plus 30 days
Title
Percentage of Participants Experiencing Clinical Laboratory Abnormalities
Time Frame
First dose date up to 53 months plus 30 days
Title
Time to Deterioration (TTD) in Global Health Status/Quality of Life (QoL) Scale as Measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core Questionnaire, Version 3.0 (EORTC QLQ-C30)
Description
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (i.e. a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (i.e. a worse state of the participant).
Time Frame
Randomization up to approximately 53 months
Title
TTD of Pain Score as Measured by EORTC QLQ-C30
Description
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (i.e. a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (i.e. a worse state of the participant).
Time Frame
Randomization up to approximately 53 months
Title
TTD of Fatigue Score as Measured by EORTC QLQ-C30
Description
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).
Time Frame
Randomization up to approximately 53 months
Title
TTD of Physical Functioning Domain Score as Measured by EORTC QLQ-C30
Description
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).
Time Frame
Randomization up to approximately 53 months
Title
TTD of Role Functioning Score as Measured by EORTC QLQ-C30
Description
The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).
Time Frame
Randomization up to approximately 53 months
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Key Inclusion Criteria:
Individuals with locally advanced, inoperable, or metastatic triple-negative breast cancer (TNBC) who have not received previous systemic therapy for advanced disease and whose tumors are programmed cell death ligand 1 (PD-L1) positive at screening.
Individuals must have completed treatment for Stage I to III breast cancer, if indicated, and ≥ 6 months must have elapsed between completion of treatment with curative intent and first documented local or distant disease recurrence.
Individuals presenting with de novo metastatic TNBC are eligible for this study.
TNBC status and tumor PD-L1 combined positive score (CPS) will be confirmed centrally on a recent or archival tumor specimen.
Individuals must have measurable disease by computed tomography (CT) or magnetic resonance imaging (MRI) as per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1 criteria as evaluated locally.
Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1.
Demonstrates adequate organ function
Male and female individuals of childbearing potential who engage in heterosexual intercourse must agree to use protocol-specified method(s) of contraception.
Individuals with HIV must be on antiretroviral therapy (ART) and have a well-controlled HIV infection/disease.
Key Exclusion Criteria:
Positive serum pregnancy test or women who are lactating.
Received prior therapy with an agent directed to another stimulatory or coinhibitory T-cell receptor.
Individuals may not have received systemic anticancer treatment within the previous 6 months or radiation therapy within 2 weeks prior to enrollment.
Individuals may not be participating in a study with an investigational agent or investigational device within 4 weeks prior to randomization. Individuals participating in observational studies are eligible.
Have previously received topoisomerase 1 inhibitors or antibody drug conjugates containing a topoisomerase inhibitor.
Have an active second malignancy.
Have active serious infection requiring antibiotics.
Individuals positive for HIV-1 or 2 with a history of Kaposi sarcoma and/or Multicentric Castleman Disease.
Have active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.
Has an active autoimmune disease that has required systemic treatment in the past 2 years.
Note: Other protocol defined Inclusion/Exclusion criteria may apply.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Gilead Clinical Study Information Center
Phone
1-833-445-3230 (GILEAD-0)
Email
GileadClinicalTrials@gilead.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Gilead Study Director
Organizational Affiliation
Gilead Sciences
Official's Role
Study Director
Facility Information:
Facility Name
Alaska Oncology and Hematology
City
Anchorage
State/Province
Alaska
ZIP/Postal Code
99508
Country
United States
Individual Site Status
Recruiting
Facility Name
Arizona Oncology Associates, PC-Hope,1845 W Orange Grove Rd
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85704
Country
United States
Individual Site Status
Recruiting
Facility Name
Arizona Oncology Associates, PC-Hope,2070 W. Rudasill Rd.
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85704
Country
United States
Individual Site Status
Recruiting
Facility Name
Arizona Oncology Associates, PC-Hope
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85711
Country
United States
Individual Site Status
Recruiting
Facility Name
Arizona Oncology Associates, PC-Hope,1620 West St. Mary's Road
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85745
Country
United States
Individual Site Status
Recruiting
Facility Name
Genesis Cancer and Blood Institute
City
Hot Springs
State/Province
Arkansas
ZIP/Postal Code
71913
Country
United States
Individual Site Status
Recruiting
Facility Name
Genesis Cancer and Blood Institute,1456 Higdon Ferry Road Suite B.
City
Hot Springs
State/Province
Arkansas
ZIP/Postal Code
71914
Country
United States
Individual Site Status
Recruiting
Facility Name
Saint Bernards Medical Center
City
Jonesboro
State/Province
Arkansas
ZIP/Postal Code
72401
Country
United States
Individual Site Status
Recruiting
Facility Name
Saint Bernards Medical Center,4000 Linwood Drive
City
Paragould
State/Province
Arkansas
ZIP/Postal Code
72450
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center,201 S. Buena Vista Street, Suite 200
City
Burbank
State/Province
California
ZIP/Postal Code
91505
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Irvine Health Chao Family,1640 Newport Blvd
City
Costa Mesa
State/Province
California
ZIP/Postal Code
92627
Country
United States
Individual Site Status
Recruiting
Facility Name
City of Hope
City
Duarte
State/Province
California
ZIP/Postal Code
91010
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California San Diego Moores Cancer
City
La Jolla
State/Province
California
ZIP/Postal Code
92093
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center,24302 Paseo de Valencia, Suite 200
City
Laguna Hills
State/Province
California
ZIP/Postal Code
91505
Country
United States
Individual Site Status
Recruiting
Facility Name
Cancer and Blood Specialty Clinic
City
Los Alamitos
State/Province
California
ZIP/Postal Code
90720
Country
United States
Individual Site Status
Recruiting
Facility Name
City of Hope,1601 Avocado Ave
City
Newport
State/Province
California
ZIP/Postal Code
92660
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Irvine Health Chao Family
City
Orange
State/Province
California
ZIP/Postal Code
92868
Country
United States
Individual Site Status
Recruiting
Facility Name
City of Hope,209 Fair Oaks Ave
City
Pasadena
State/Province
California
ZIP/Postal Code
91030
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center,892 Aerovista Place, Suite 240
City
San Luis Obispo
State/Province
California
ZIP/Postal Code
93401
Country
United States
Individual Site Status
Recruiting
Facility Name
Sansum Clinic
City
Santa Barbara
State/Province
California
ZIP/Postal Code
93105
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center,2020 Santa Monica Blvd, Suite 600
City
Santa Monica
State/Province
California
ZIP/Postal Code
90404
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center,2336 Santa Monica, Suites 302 and 304
City
Santa Monica
State/Province
California
ZIP/Postal Code
90404
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center
City
Santa Monica
State/Province
California
ZIP/Postal Code
90404
Country
United States
Individual Site Status
Recruiting
Facility Name
St. Jude Hospital Yorba dba St. Joseph Heritage Healthcare
City
Santa Rosa
State/Province
California
ZIP/Postal Code
95403
Country
United States
Individual Site Status
Recruiting
Facility Name
Sansum Clinic,2040 Viborg Road
City
Solvang
State/Province
California
ZIP/Postal Code
93463
Country
United States
Individual Site Status
Recruiting
Facility Name
City of Hope,5215 Torrance Blvd
City
Torrance
State/Province
California
ZIP/Postal Code
90503
Country
United States
Individual Site Status
Recruiting
Facility Name
Torrance Memorial Physician Network - Cancer Care
City
Torrance
State/Province
California
ZIP/Postal Code
90505
Country
United States
Individual Site Status
Recruiting
Facility Name
City of Hope,1100 San Bernardino Rd
City
Upland
State/Province
California
ZIP/Postal Code
91786
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California Los Angeles - Jonsson Comprehensive Cancer Center,1250 La Venta Dr, Suite 100
City
Westlake Village
State/Province
California
ZIP/Postal Code
91361
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,1700 South Potomac Street
City
Aurora
State/Province
Colorado
ZIP/Postal Code
80012
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers
City
Boulder
State/Province
Colorado
ZIP/Postal Code
80303
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,2312 N. Nevada Avenue
City
Colorado Springs
State/Province
Colorado
ZIP/Postal Code
80907
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,6031 E. Woodman Rd.
City
Colorado Springs
State/Province
Colorado
ZIP/Postal Code
80923
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,4700 E. Hale Parkway
City
Denver
State/Province
Colorado
ZIP/Postal Code
80220
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,11750 West 2nd Place
City
Lakewood
State/Province
Colorado
ZIP/Postal Code
80228
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,22 West Dry Creek Circle
City
Littleton
State/Province
Colorado
ZIP/Postal Code
80120
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,10107 Ridge Gate Parkway
City
Lone Tree
State/Province
Colorado
ZIP/Postal Code
80124
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,2030 Mountain View Ave Ste 210
City
Longmont
State/Province
Colorado
ZIP/Postal Code
80124
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,3676 Parker Blvd
City
Pueblo
State/Province
Colorado
ZIP/Postal Code
81008
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,525 W. 15th Street
City
Pueblo
State/Province
Colorado
ZIP/Postal Code
81008
Country
United States
Individual Site Status
Recruiting
Facility Name
Rocky Mountain Cancer Centers,8820 Huron Street
City
Thornton
State/Province
Colorado
ZIP/Postal Code
80260
Country
United States
Individual Site Status
Recruiting
Facility Name
Eastern Connecticut Hematology and Oncology Associates
City
Norwich
State/Province
Connecticut
ZIP/Postal Code
06360
Country
United States
Individual Site Status
Recruiting
Facility Name
Advent Health Medical Group
City
Altamonte Springs
State/Province
Florida
ZIP/Postal Code
32701
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,106 Boston Ave
City
Altamonte Springs
State/Province
Florida
ZIP/Postal Code
32701
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,2801 NE 213th St
City
Aventura
State/Province
Florida
ZIP/Postal Code
33180
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,9776 Bonita Beach Road Southeast Suite 201 A
City
Bonita Springs
State/Province
Florida
ZIP/Postal Code
34135
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,3630 Manatee Avenue West
City
Bradenton
State/Province
Florida
ZIP/Postal Code
34205
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,5985 Silver Falls Run
City
Bradenton
State/Province
Florida
ZIP/Postal Code
34211
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,403 S. Kings Ave.
City
Brandon
State/Province
Florida
ZIP/Postal Code
33511
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,1030 Commerce Creek Blvd
City
Cape Coral
State/Province
Florida
ZIP/Postal Code
33909
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,3280 McMullen Booth Road
City
Clearwater
State/Province
Florida
ZIP/Postal Code
33761
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,5555 Ponce De Leon Blvd
City
Coral Gables
State/Province
Florida
ZIP/Postal Code
33146
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - West Palm Beach,224 Memorial Medical Parkway, Suite 300
City
Daytona Beach
State/Province
Florida
ZIP/Postal Code
32117
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,1192 East Newport Center Drive
City
Deerfield Beach
State/Province
Florida
ZIP/Postal Code
33442
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33901
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,8981 Colonial Center Drive
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33905
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,8260 Gladiolus Dr
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33908
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,6420 W. Newberry Road
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32605
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,3850 Hollywood Blvd
City
Hollywood
State/Province
Florida
ZIP/Postal Code
33021
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,100 Highland Avenue
City
Largo
State/Province
Florida
ZIP/Postal Code
33770
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,521 North Lecanto Highway
City
Lecanto
State/Province
Florida
ZIP/Postal Code
34461
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,1400 NW 12th Ave
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,8932 S.W. 97 Ave
City
Miami
State/Province
Florida
ZIP/Postal Code
33176
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,1100 Goodlette Road
City
Naples
State/Province
Florida
ZIP/Postal Code
34102
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,4945 SW 49th Place
City
Ocala
State/Province
Florida
ZIP/Postal Code
34474
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,765 Image Way
City
Orange City
State/Province
Florida
ZIP/Postal Code
32763
Country
United States
Individual Site Status
Recruiting
Facility Name
Advent Health Medical Group,2501 North Orange Ave
City
Orlando
State/Province
Florida
ZIP/Postal Code
32804
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,70 W. Gore Street
City
Orlando
State/Province
Florida
ZIP/Postal Code
32806
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Miami - Sylvester Comprehensive Cancer Center,8100 SW 10 Street
City
Plantation
State/Province
Florida
ZIP/Postal Code
33324
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,22395 Edgewater Drive
City
Port Charlotte
State/Province
Florida
ZIP/Postal Code
33980
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,1201 Fifth Avenue North
City
Saint Petersburg
State/Province
Florida
ZIP/Postal Code
33705
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R
City
Saint Petersburg
State/Province
Florida
ZIP/Postal Code
33705
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,600 North Cattlemen Road
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34232
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,1970 Golf Street
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34236
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,7154 Medical Center Drive
City
Spring Hill
State/Province
Florida
ZIP/Postal Code
34608
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - West Palm Beach,301 SE Ocean Blvd, Suite 102
City
Stuart
State/Province
Florida
ZIP/Postal Code
34994
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,3402 West Dr. Martin Luther King Jr. Boulevard
City
Tampa
State/Province
Florida
ZIP/Postal Code
33607
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,4100 Waterman Way
City
Tavares
State/Province
Florida
ZIP/Postal Code
32778
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,1400 US Highway 441 N
City
The Villages
State/Province
Florida
ZIP/Postal Code
32159
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,9320 State Road 54
City
Trinity
State/Province
Florida
ZIP/Postal Code
34655
Country
United States
Individual Site Status
Recruiting
Facility Name
Florida Cancer Specialists,836 Sunset Lake Blvd
City
Venice
State/Province
Florida
ZIP/Postal Code
34292
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - West Palm Beach,3730 7th Terrace, Suite 101
City
Vero Beach
State/Province
Florida
ZIP/Postal Code
32960
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - West Palm Beach,1037 S. State Road 7, Bldg B, Suite 303
City
Wellington
State/Province
Florida
ZIP/Postal Code
33414
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - West Palm Beach
City
West Palm Beach
State/Province
Florida
ZIP/Postal Code
33401
Country
United States
Individual Site Status
Recruiting
Facility Name
SCRI - Florida Cancer Specialists - North Region R,460 N Orlando Ave
City
Winter Park
State/Province
Florida
ZIP/Postal Code
32789
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,125 King Avenue
City
Athens
State/Province
Georgia
ZIP/Postal Code
30606
Country
United States
Individual Site Status
Recruiting
Facility Name
Piedmont Cancer Institute - Atlanta,1267 Hwy 54W
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30214
Country
United States
Individual Site Status
Recruiting
Facility Name
Winship Cancer Institute of Emory University,550 Peachtree St NE
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30308
Country
United States
Individual Site Status
Recruiting
Facility Name
Piedmont Cancer Institute - Atlanta
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30318
Country
United States
Individual Site Status
Recruiting
Facility Name
Winship Cancer Institute of Emory University
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,5670 Peachtree Dunwoody Rd.
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Individual Site Status
Recruiting
Facility Name
Winship Cancer Institute of Emory University,5665 Peachtree Dunwoody Road
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,308 Deep South Farm Rd, Suite 200
City
Blairsville
State/Province
Georgia
ZIP/Postal Code
30512
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,228 Riverstone Dr.
City
Canton
State/Province
Georgia
ZIP/Postal Code
30114
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,1505 Northside Blvd, Suite 4600
City
Cumming
State/Province
Georgia
ZIP/Postal Code
30041
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,3855 Pleasant Hill Rd., Suite 480
City
Duluth
State/Province
Georgia
ZIP/Postal Code
30096
Country
United States
Individual Site Status
Recruiting
Facility Name
Northside Hospital,308 Coliseum Dr.
City
Macon
State/Province
Georgia
ZIP/Postal Code
31217
Country
United States
Individual Site Status
Recruiting
Facility Name
Piedmont Cancer Institute - Atlanta,775 Poplar Road
City
Newnan
State/Province
Georgia
ZIP/Postal Code
30265
Country
United States
Individual Site Status
Recruiting
Facility Name
Piedmont Cancer Institute - Atlanta,1240 Eagles Landing Pkwy
City
Stockbridge
State/Province
Georgia
ZIP/Postal Code
30281
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60611
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Illinois Hospital and Health Sciences System (Outpatient Cancer Center)
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60612
Country
United States
Individual Site Status
Recruiting
Facility Name
Orchard Healthcare Research Inc,2845 North Sheridan Road, 1st Floor
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60657
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1 Kish Hospital Drive
City
DeKalb
State/Province
Illinois
ZIP/Postal Code
60115
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,10 Health Services Drive
City
DeKalb
State/Province
Illinois
ZIP/Postal Code
60115
Country
United States
Individual Site Status
Recruiting
Facility Name
Orchard Healthcare Research Inc,800 Austin Street, Suite 360, East Tower
City
Evanston
State/Province
Illinois
ZIP/Postal Code
60202
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,300 Randall Road
City
Geneva
State/Province
Illinois
ZIP/Postal Code
60134
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,304 Randall Road
City
Geneva
State/Province
Illinois
ZIP/Postal Code
60134
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1000 N. Westmoreland Road
City
Lake Forest
State/Province
Illinois
ZIP/Postal Code
60045
Country
United States
Individual Site Status
Recruiting
Facility Name
Orchard Healthcare Research Inc
City
Skokie
State/Province
Illinois
ZIP/Postal Code
60077
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4405 Weaver Parkway
City
Warrenville
State/Province
Illinois
ZIP/Postal Code
25731
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4455 Weaver Parkway
City
Warrenville
State/Province
Illinois
ZIP/Postal Code
60555
Country
United States
Individual Site Status
Recruiting
Facility Name
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,25 N Winfield Road
City
Winfield
State/Province
Illinois
ZIP/Postal Code
60190
Country
United States
Individual Site Status
Recruiting
Facility Name
Regulatory Management Only: TRIO-US Central Administration
City
Fort Wayne
State/Province
Indiana
ZIP/Postal Code
46845
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,2000 Olathe Blvd
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,12200 W. 110th Street
City
Overland Park
State/Province
Kansas
ZIP/Postal Code
66210
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,10710 Nall Avenue
City
Overland Park
State/Province
Kansas
ZIP/Postal Code
66211
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,10730 Nall Avenue
City
Overland Park
State/Province
Kansas
ZIP/Postal Code
66211
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center
City
Westwood
State/Province
Kansas
ZIP/Postal Code
66205
Country
United States
Individual Site Status
Recruiting
Facility Name
Norton Cancer Institute - Saint Matthews,234 E. Gray Strret
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40202
Country
United States
Individual Site Status
Recruiting
Facility Name
Norton Cancer Institute - Saint Matthews,676 S. Floyd Street
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40202
Country
United States
Individual Site Status
Recruiting
Facility Name
Norton Cancer Institute - Saint Matthews
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40207
Country
United States
Individual Site Status
Recruiting
Facility Name
Norton Cancer Institute - Saint Matthews,4955 Norton Healthcare Blvd
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40241
Country
United States
Individual Site Status
Recruiting
Facility Name
Hematology Oncology Clinic - Baton Rouge
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70809
Country
United States
Individual Site Status
Recruiting
Facility Name
Hematology Oncology Clinic - Baton Rouge,1673 E Mount Please Drive
City
Zachary
State/Province
Louisiana
ZIP/Postal Code
70791
Country
United States
Individual Site Status
Recruiting
Facility Name
Cancer Institute Ascension Saint Agnes
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21229
Country
United States
Individual Site Status
Recruiting
Facility Name
Beth Israel Deaconess Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Individual Site Status
Recruiting
Facility Name
Dana-Farber Cancer Institute
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Individual Site Status
Recruiting
Facility Name
Massachusetts General Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Individual Site Status
Recruiting
Facility Name
Massachusetts General Hospital,102 Endicott Street
City
Danvers
State/Province
Massachusetts
ZIP/Postal Code
01923
Country
United States
Individual Site Status
Recruiting
Facility Name
Massachusetts General Hospital,2014 Washington St
City
Newton
State/Province
Massachusetts
ZIP/Postal Code
02462
Country
United States
Individual Site Status
Recruiting
Facility Name
Ascension St. John Hospital
City
Grosse Pointe Woods
State/Province
Michigan
ZIP/Postal Code
48236
Country
United States
Individual Site Status
Recruiting
Facility Name
Ascension Providence Hospital Southfield Cancer Center
City
Southfield
State/Province
Michigan
ZIP/Postal Code
48075
Country
United States
Individual Site Status
Recruiting
Facility Name
Mayo Clinic
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55905
Country
United States
Individual Site Status
Recruiting
Facility Name
The West Clinic, PLLC dba West Cancer Center,7668 Airways Blvd
City
Southaven
State/Province
Mississippi
ZIP/Postal Code
38671
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,2750 Clay Edwards Drive
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64116
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,8700 North Green Hills Road
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64154
Country
United States
Individual Site Status
Recruiting
Facility Name
The University of Kansas Cancer Center,4881 N.E. Goodview Circle
City
Lee's Summit
State/Province
Missouri
ZIP/Postal Code
64064
Country
United States
Individual Site Status
Recruiting
Facility Name
Nebraska Cancer Specialists,2730 W. Faidley Ave
City
Grand Island
State/Province
Nebraska
ZIP/Postal Code
68114
Country
United States
Individual Site Status
Recruiting
Facility Name
Nebraska Cancer Specialists,8303 Dodge Street
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68114
Country
United States
Individual Site Status
Recruiting
Facility Name
Nebraska Cancer Specialists
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68130
Country
United States
Individual Site Status
Recruiting
Facility Name
Nebraska Cancer Specialists,611 Fenwick Dr
City
Papillion
State/Province
Nebraska
ZIP/Postal Code
68046
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V,10001 S. Eastern Avenue, Suite 108
City
Henderson
State/Province
Nevada
ZIP/Postal Code
89052
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V,2460 W. Horizon Ridge Parkway
City
Henderson
State/Province
Nevada
ZIP/Postal Code
89052
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V,1501 Wigwam Parkway, Suite 1300
City
Henderson
State/Province
Nevada
ZIP/Postal Code
89074
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V,653 North Town Center Drive, Suite 402
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89144
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V,9280 W. Sunset Road Suite 100
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89148
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V,7445 Peak Drive
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89169
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Cancer Centers of Nevada - Central V
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89169
Country
United States
Individual Site Status
Recruiting
Facility Name
Summit Medical Group,1 Diamond Hill Road
City
Berkeley Heights
State/Province
New Jersey
ZIP/Postal Code
07922
Country
United States
Individual Site Status
Recruiting
Facility Name
Regional Cancer Care Associates - East Brunswick
City
East Brunswick
State/Province
New Jersey
ZIP/Postal Code
08816
Country
United States
Individual Site Status
Recruiting
Facility Name
Summit Medical Group
City
Florham Park
State/Province
New Jersey
ZIP/Postal Code
07932
Country
United States
Individual Site Status
Recruiting
Facility Name
John Theurer Cancer Center
City
Hackensack
State/Province
New Jersey
ZIP/Postal Code
07601
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,2575 Klockner Road
City
Hamilton
State/Province
New Jersey
ZIP/Postal Code
08690
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,414 Grand Street
City
Jersey City
State/Province
New Jersey
ZIP/Postal Code
07302
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,600 River Avenue
City
Lakewood
State/Province
New Jersey
ZIP/Postal Code
08701
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,94 Old Short Hills Road
City
Livingston
State/Province
New Jersey
ZIP/Postal Code
07039
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,300 Second Ave
City
Long Branch
State/Province
New Jersey
ZIP/Postal Code
07740
Country
United States
Individual Site Status
Recruiting
Facility Name
Regional Cancer Care Associates - East Brunswick,9 Centre Drive
City
Monroe
State/Province
New Jersey
ZIP/Postal Code
08831
Country
United States
Individual Site Status
Recruiting
Facility Name
Regional Cancer Care Associates - East Brunswick,34-36 Progress Street
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08820
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08901
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,150 Bergen St.
City
Newark
State/Province
New Jersey
ZIP/Postal Code
07103
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,201 Lyons Avenue
City
Newark
State/Province
New Jersey
ZIP/Postal Code
07112
Country
United States
Individual Site Status
Recruiting
Facility Name
Regional Cancer Care Associates - East Brunswick,75 Veronica Avenue
City
Somerset
State/Province
New Jersey
ZIP/Postal Code
08873
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,110 Rehill Ave
City
Somerville
State/Province
New Jersey
ZIP/Postal Code
08876
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,99 Highway 37 West
City
Toms River
State/Province
New Jersey
ZIP/Postal Code
08755
Country
United States
Individual Site Status
Recruiting
Facility Name
Rutgers Cancer Institute of New Jersey,100 State Route 36
City
West Long Branch
State/Province
New Jersey
ZIP/Postal Code
07764
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,72 East Main St.
City
Babylon
State/Province
New York
ZIP/Postal Code
11702
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,12 East 86th St, Suite 4
City
Bronx
State/Province
New York
ZIP/Postal Code
10028
Country
United States
Individual Site Status
Recruiting
Facility Name
Montefiore Medical Center - Montefiore Medical Park
City
Bronx
State/Province
New York
ZIP/Postal Code
10467
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,2330 Eastchester Road, Suite 360
City
Bronx
State/Province
New York
ZIP/Postal Code
10469
Country
United States
Individual Site Status
Recruiting
Facility Name
Perlmutter Cancer Center - Manhattan - 34th Street,259 First Street
City
Mineola
State/Province
New York
ZIP/Postal Code
11501
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,1 Delaware Dr.
City
New Hyde Park
State/Province
New York
ZIP/Postal Code
11042
Country
United States
Individual Site Status
Recruiting
Facility Name
Perlmutter Cancer Center - Manhattan - 34th Street
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Individual Site Status
Recruiting
Facility Name
NYP/Columbia Univeresity Medical Center/Herbert Irving Comprehensive Cancer Center
City
New York
State/Province
New York
ZIP/Postal Code
10032
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,365 East Main St.
City
Patchogue
State/Province
New York
ZIP/Postal Code
11772
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,49 Rte. 347, Newconset Hwy
City
Port Jefferson Station
State/Province
New York
ZIP/Postal Code
11776
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers
City
Port Jefferson Station
State/Province
New York
ZIP/Postal Code
11776
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,1500 Rte, 112, Building 4
City
Port Jefferson
State/Province
New York
ZIP/Postal Code
11776
Country
United States
Individual Site Status
Recruiting
Facility Name
New York Cancer & Blood Specialists - Port Jeffers,750 Old County Rd. Suite 4
City
Riverhead
State/Province
New York
ZIP/Postal Code
11901
Country
United States
Individual Site Status
Recruiting
Facility Name
The Ohio State University Wexner Medical Center Clinical Laboratories
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43212
Country
United States
Individual Site Status
Recruiting
Facility Name
Zangmeister Cancer Center
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43219
Country
United States
Individual Site Status
Recruiting
Facility Name
Northwest Cancer Specialists, PC,5050 NE Hoyt St.
City
Portland
State/Province
Oregon
ZIP/Postal Code
97213
Country
United States
Individual Site Status
Recruiting
Facility Name
Northwest Cancer Specialists, PC,265 N. Broadway
City
Portland
State/Province
Oregon
ZIP/Postal Code
97227
Country
United States
Individual Site Status
Recruiting
Facility Name
Northwest Cancer Specialists, PC
City
Tigard
State/Province
Oregon
ZIP/Postal Code
97223
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,200 Oxford Drive
City
Bethel Park
State/Province
Pennsylvania
ZIP/Postal Code
15102
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,3 St. Francis Way
City
Cranberry Township
State/Province
Pennsylvania
ZIP/Postal Code
16066
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,2500 West 12th Street
City
Erie
State/Province
Pennsylvania
ZIP/Postal Code
16505
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,201 State Street, 6 Main
City
Erie
State/Province
Pennsylvania
ZIP/Postal Code
16550
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,200 Village Drive
City
Greensburg
State/Province
Pennsylvania
ZIP/Postal Code
15601
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,4300 Londonberry Road
City
Harrisburg
State/Province
Pennsylvania
ZIP/Postal Code
17109
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,400 Oxford Drive
City
Monroeville
State/Province
Pennsylvania
ZIP/Postal Code
15146
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Pennsylvania Abramson Cancer Center
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15213
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,5115 Centre Avenue
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15232
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,9100 Babcock Boulevard
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15237
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,100 Fairfield Dr
City
Seneca
State/Province
Pennsylvania
ZIP/Postal Code
16346
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,470 Johnson Road
City
Washington
State/Province
Pennsylvania
ZIP/Postal Code
15301
Country
United States
Individual Site Status
Recruiting
Facility Name
Magee-Womens Hospital of UPMC,1703 Innovation Drive
City
York
State/Province
Pennsylvania
ZIP/Postal Code
17408
Country
United States
Individual Site Status
Recruiting
Facility Name
Rhode Island Hospital
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02903
Country
United States
Individual Site Status
Recruiting
Facility Name
Rhode Island Hospital,164 Summit Ave, Fain 275A
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02906
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,103 Natchez Park Drive
City
Dickson
State/Province
Tennessee
ZIP/Postal Code
37055
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,4488 Carothers Parkway
City
Franklin
State/Province
Tennessee
ZIP/Postal Code
37067
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,225 Big Station Camp Blvd
City
Gallatin
State/Province
Tennessee
ZIP/Postal Code
37066
Country
United States
Individual Site Status
Recruiting
Facility Name
The West Clinic, PLLC dba West Cancer Center
City
Germantown
State/Province
Tennessee
ZIP/Postal Code
38138
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,353 New Shackle Island Road
City
Hendersonville
State/Province
Tennessee
ZIP/Postal Code
37075
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,5653 First Blvd.
City
Hermitage
State/Province
Tennessee
ZIP/Postal Code
37076
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,103 Physicians Way
City
Lebanon
State/Province
Tennessee
ZIP/Postal Code
37090
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,1840 Medical Center Parkway
City
Murfreesboro
State/Province
Tennessee
ZIP/Postal Code
37129
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,2004 Hayes Street
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,4220 Harding Rd
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37205
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,3443 Dickerson Road
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37207
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,397 Wallace Road
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37211
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,120 Frank Martin Road
City
Shelbyville
State/Province
Tennessee
ZIP/Postal Code
37160
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Oncology, PLLC,300 Stonecrest Blvd
City
Smyrna
State/Province
Tennessee
ZIP/Postal Code
37167
Country
United States
Individual Site Status
Recruiting
Facility Name
The Center for Cancer and Blood Disorders - Magnolia,515 W. Mayfield Rd.
City
Arlington
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Oncology-Austin,901 West 38th Street
City
Austin
State/Province
Texas
ZIP/Postal Code
78705
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Oncology-Austin
City
Austin
State/Province
Texas
ZIP/Postal Code
78731
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Oncology-Austin,4101 James Casey, Suite 100
City
Austin
State/Province
Texas
ZIP/Postal Code
78745
Country
United States
Individual Site Status
Recruiting
Facility Name
The Center for Cancer and Blood Disorders - Magnolia,11805 South Freeway
City
Burleson
State/Province
Texas
ZIP/Postal Code
76028
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Oncology-Baylor Charles A. Sammons Cancer Center
City
Dallas
State/Province
Texas
ZIP/Postal Code
75246
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Oncology-Denison
City
Denison
State/Province
Texas
ZIP/Postal Code
75020
Country
United States
Individual Site Status
Recruiting
Facility Name
The Center for Cancer and Blood Disorders - Magnolia
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Individual Site Status
Recruiting
Facility Name
Oncology Consultants,1631 North Loop West
City
Houston
State/Province
Texas
ZIP/Postal Code
77008
Country
United States
Individual Site Status
Recruiting
Facility Name
Oncology Consultants,925 Gessner
City
Houston
State/Province
Texas
ZIP/Postal Code
77024
Country
United States
Individual Site Status
Recruiting
Facility Name
Oncology Consultants
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Texas MD Anderson Cancer Center,1155 Pressler St
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Texas MD Anderson Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Name
Mays Cancer Center
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Individual Site Status
Recruiting
Facility Name
The Center for Cancer and Blood Disorders - Magnolia,920 Santa Fe Drive
City
Weatherford
State/Province
Texas
ZIP/Postal Code
76086
Country
United States
Individual Site Status
Recruiting
Facility Name
Huntsman Cancer Institute, University of Utah,165 North University Avenue
City
Farmington
State/Province
Utah
ZIP/Postal Code
84025
Country
United States
Individual Site Status
Recruiting
Facility Name
Huntsman Cancer Institute, University of Utah,1280 E. Stringham Avenue
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84106
Country
United States
Individual Site Status
Recruiting
Facility Name
Huntsman Cancer Institute, University of Utah
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84112
Country
United States
Individual Site Status
Recruiting
Facility Name
Huntsman Cancer Institute, University of Utah,5126 West Daybreak Parkway
City
South Jordan
State/Province
Utah
ZIP/Postal Code
84009
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Oncology Associates,744 N. Battlefield Blvd
City
Chesapeake
State/Province
Virginia
ZIP/Postal Code
23320
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Cancer Institute,7501 Right Flank Road
City
Mechanicsville
State/Province
Virginia
ZIP/Postal Code
23116
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Oncology Associates,1051 Loftis Blvd Suite 100
City
Newport News
State/Province
Virginia
ZIP/Postal Code
23606
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Oncology Associates
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Cancer Institute,210 Medical Park Boulevard
City
Petersburg
State/Province
Virginia
ZIP/Postal Code
23805
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Cancer Institute,1401 Johnston-Willis Drive
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23235
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Cancer Institute
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
Individual Site Status
Recruiting
Facility Name
Virginia Oncology Associates,1950 Glenn Mitchell Drive
City
Virginia Beach
State/Province
Virginia
ZIP/Postal Code
23456
Country
United States
Individual Site Status
Recruiting
Facility Name
Northwest Cancer Specialists, PC,210 SE 136th Avenue
City
Vancouver
State/Province
Washington
ZIP/Postal Code
98684
Country
United States
Individual Site Status
Recruiting
Facility Name
Hospital Británico de Buenos Aires
City
Buenos Aires
ZIP/Postal Code
1426
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Instituto de Oncología Ángel H. Roffo
City
Caba
ZIP/Postal Code
1417
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Fundacion CORI para la Investigacioy y Prevención del Cancer
City
Capital
ZIP/Postal Code
F5300COE
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Instituto de Oncologia de Rosario
City
Rosario
ZIP/Postal Code
2000
Country
Argentina
Individual Site Status
Recruiting
Facility Name
CAIPO Centro Para La Atención Integral Del Pacient
City
San Miguel de Tucumán
ZIP/Postal Code
4000
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Clinica Viedma
City
Viedma
ZIP/Postal Code
8500
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Border Medical Oncology
City
Albury
State/Province
New South Wales
ZIP/Postal Code
2640
Country
Australia
Individual Site Status
Recruiting
Facility Name
Saint George Hospital - Australia
City
Kogarah
State/Province
New South Wales
ZIP/Postal Code
2217
Country
Australia
Individual Site Status
Recruiting
Facility Name
Mater Hospital - North Sydney
City
North Sydney
State/Province
New South Wales
ZIP/Postal Code
2060
Country
Australia
Individual Site Status
Recruiting
Facility Name
GenesisCare - North Shore
City
St Leonards
State/Province
New South Wales
ZIP/Postal Code
2065
Country
Australia
Individual Site Status
Recruiting
Facility Name
Mater Misericordiae Limited and Mater Research Limited
City
South Brisbane
State/Province
Queensland
ZIP/Postal Code
4101
Country
Australia
Individual Site Status
Recruiting
Facility Name
Princess Alexandra Hospital
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Individual Site Status
Recruiting
Facility Name
Cancer Research SA (CRSA)
City
Adelaide
State/Province
South Australia
ZIP/Postal Code
5000
Country
Australia
Individual Site Status
Recruiting
Facility Name
Icon Cancer Centre Hobart
City
Hobart
State/Province
Tasmania
ZIP/Postal Code
7000
Country
Australia
Individual Site Status
Recruiting
Facility Name
Monash Medical Centre
City
Clayton
State/Province
Victoria
ZIP/Postal Code
3168
Country
Australia
Individual Site Status
Recruiting
Facility Name
Austin Hospital
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3084
Country
Australia
Individual Site Status
Recruiting
Facility Name
Peter MacCallum Cancer Centre
City
Parkville
State/Province
Victoria
ZIP/Postal Code
3050
Country
Australia
Individual Site Status
Recruiting
Facility Name
Breast Cancer Research Center - Western Australia
City
Nedlands
State/Province
Western Australia
ZIP/Postal Code
6009
Country
Australia
Individual Site Status
Recruiting
Facility Name
Medizinische Universität Innsbruck
City
Innsbruck
ZIP/Postal Code
06020
Country
Austria
Individual Site Status
Recruiting
Facility Name
Ordensklinikum Linz GmbH Barmherzige Schwestern
City
Linz
ZIP/Postal Code
4010
Country
Austria
Individual Site Status
Recruiting
Facility Name
Landeskrankenhaus Salzburg
City
Salzburg
ZIP/Postal Code
A-5020
Country
Austria
Individual Site Status
Recruiting
Facility Name
Universitätsklinikum Sankt Pölten
City
Sankt Poelten
ZIP/Postal Code
3100
Country
Austria
Individual Site Status
Recruiting
Facility Name
Medizinische Universität Wien
City
Wien
ZIP/Postal Code
1090
Country
Austria
Individual Site Status
Recruiting
Facility Name
Institut Jules Bordet
City
Anderlecht
ZIP/Postal Code
1070
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Algemeen Ziekenhuis Klina
City
Brasschaat
ZIP/Postal Code
2930
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Cliniques Universitaires Saint-Luc
City
Brussels
ZIP/Postal Code
1200
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Universitair Ziekenhuis Brussel
City
Brussels
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Grand Hopital de Charleroi - Notre Dame
City
Charleroi
ZIP/Postal Code
6000
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Universitair Ziekenhuis Gent
City
Gent
ZIP/Postal Code
9000
Country
Belgium
Individual Site Status
Recruiting
Facility Name
UZ Leuven
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Centre Hospitalier Universitaire Université Cathol
City
Namur
ZIP/Postal Code
5000
Country
Belgium
Individual Site Status
Recruiting
Facility Name
Hospital Araújo Jorge - Associacao de Combate ao Cancer em Goias - ACCG
City
Goiânia
ZIP/Postal Code
74605-070
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Centro de Pesquisa Clinica Em Oncologia - ONCOSITE
City
Ijui
ZIP/Postal Code
98700-000
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital de Clinicas de Porto Alegre - HCPA
City
Itajai
ZIP/Postal Code
88331-10
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Centro de Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho - Hospital Amarval Carvalho
City
Jau
ZIP/Postal Code
17210080
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Associacao Hosptialar Moinos de Vento - Hospital Moinhos de Vento
City
Porto Alegre
ZIP/Postal Code
90035-00
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital de Clínicas de Porto Alegre
City
Porto Alegre
ZIP/Postal Code
90035-903
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Hospital Sao Lucas da PUCRS
City
Porto Alegre
ZIP/Postal Code
90610001
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Instituto Nacional de Câncer - Brazil
City
Rio de Janeiro
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Núcleo de Oncologia da Bahia
City
Salvador
ZIP/Postal Code
40170170
Country
Brazil
Individual Site Status
Recruiting
Facility Name
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Centro Universitário FMABC
City
Santo Andre
ZIP/Postal Code
09060-650
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Real e Benemerita Associacao Portuguesa de Beneficencia - Hospital Beneficencia Portuguesa (BP) - Unidade Paulista
City
São Paulo
ZIP/Postal Code
01323-001
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Clinica de Pesquisas e Centro de Estudos em Oncolo
City
São Paulo
ZIP/Postal Code
1317000
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Fundação Pio XII - Hospital de Câncer de Barretos
City
São Paulo
ZIP/Postal Code
14784400
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Nucleo de Pesquisa Clinica da Rede Sao Camilo
City
São Paulo
ZIP/Postal Code
4014002
Country
Brazil
Individual Site Status
Recruiting
Facility Name
Tom Baker Cancer Centre
City
Calgary
ZIP/Postal Code
T2N 2T9
Country
Canada
Individual Site Status
Recruiting
Facility Name
Cross Cancer Institute
City
Edmonton
ZIP/Postal Code
T6G 1Z2
Country
Canada
Individual Site Status
Recruiting
Facility Name
QEII Health Sciences Centre
City
Halifax
ZIP/Postal Code
B3H 1V7
Country
Canada
Individual Site Status
Recruiting
Facility Name
Grand River Regional Cancer Centre at Grand River Hospital
City
Kitchener
ZIP/Postal Code
N2G 1G3
Country
Canada
Individual Site Status
Recruiting
Facility Name
London Health Sciences Centre
City
London
ZIP/Postal Code
N6A 5W9
Country
Canada
Individual Site Status
Recruiting
Facility Name
McGill University Health Centre
City
Montreal
ZIP/Postal Code
H4A 3J1
Country
Canada
Individual Site Status
Recruiting
Facility Name
Jewish General Hospital
City
Montréal
ZIP/Postal Code
H3T 1E2
Country
Canada
Individual Site Status
Recruiting
Facility Name
Princess Margaret Cancer Centre - University Health Network
City
Ontario
ZIP/Postal Code
M5G 2M9
Country
Canada
Individual Site Status
Recruiting
Facility Name
Ottawa Hospital - General Campus
City
Ottawa
ZIP/Postal Code
K1H 8L6
Country
Canada
Individual Site Status
Recruiting
Facility Name
Sunnybrook Research Institute
City
Toronto
ZIP/Postal Code
M4N 3M5
Country
Canada
Individual Site Status
Recruiting
Facility Name
Mount Sinai Hospital
City
Toronto
ZIP/Postal Code
M5G 1X5
Country
Canada
Individual Site Status
Recruiting
Facility Name
British Columbia Cancer - Vancouver
City
Vancouver
ZIP/Postal Code
V5Z 4E6
Country
Canada
Individual Site Status
Recruiting
Facility Name
Oncovida - Santiago
City
Providencia
ZIP/Postal Code
7510035
Country
Chile
Individual Site Status
Recruiting
Facility Name
Clínica IRAM
City
Santiago DE CHILE
Country
Chile
Individual Site Status
Recruiting
Facility Name
Centro de Cancer Pontificia Universidad Catolica
City
Santiago Region
ZIP/Postal Code
8330032
Country
Chile
Individual Site Status
Recruiting
Facility Name
Clínica Alemana
City
Santiago
ZIP/Postal Code
7630000
Country
Chile
Individual Site Status
Recruiting
Facility Name
James Lind Centro de Investigacion del Cancer
City
Temuco
Country
Chile
Individual Site Status
Recruiting
Facility Name
Masarykuv Onkologicky Ustav, Klinika Komplexni Onkologicke Pece
City
Brno
ZIP/Postal Code
65653
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Fakultní Thomayerova nemocnice
City
Hradec Kralove
ZIP/Postal Code
50005
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Fakultní Nemocnice Hradec Králové
City
Hradec Králové
ZIP/Postal Code
500 05
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Fakultni nemocnice Olomouc, Onkologicka klinika
City
Olomouc
ZIP/Postal Code
77520
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Vseobecna Fakultni Nemocnice v Praze, Onkologicka klinika
City
Prague
ZIP/Postal Code
12808
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Fakultní Nemocnice Královské Vinohrady, Radioterapeuticka a onkologicka klinika
City
Praha
ZIP/Postal Code
100 34
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Sainte Catherine Institut du Cancer Avignon Provence
City
Avignon
ZIP/Postal Code
84918
Country
France
Individual Site Status
Recruiting
Facility Name
Centre Hospitalier Régional et Universitaire de Be
City
Besancon
ZIP/Postal Code
25030
Country
France
Individual Site Status
Recruiting
Facility Name
Polyclinique Bordeaux Nord Aquitaine
City
Bordeaux
ZIP/Postal Code
33000
Country
France
Individual Site Status
Recruiting
Facility Name
Hôpital Morvan, Institut de cancérologie
City
Brest
ZIP/Postal Code
29200
Country
France
Individual Site Status
Recruiting
Facility Name
Centre de Lutte contre le Cancer - François Bacles
City
Caen
ZIP/Postal Code
14000
Country
France
Individual Site Status
Recruiting
Facility Name
Centre Jean Perrin
City
Clermont Ferrand
ZIP/Postal Code
63011
Country
France
Individual Site Status
Recruiting
Facility Name
Centre Leon Berard
City
Lyon
ZIP/Postal Code
69373
Country
France
Individual Site Status
Recruiting
Facility Name
Institut Paoli-Calmettes
City
Marseille CEDEX 9
ZIP/Postal Code
13273
Country
France
Individual Site Status
Recruiting
Facility Name
Institut Régional du Cancer de Montpellier
City
Montpellier Cedex 5
ZIP/Postal Code
34298
Country
France
Individual Site Status
Recruiting
Facility Name
Centre de Cancérologie du Grand Montpellier
City
Montpellier
ZIP/Postal Code
34070
Country
France
Individual Site Status
Recruiting
Facility Name
Hôpital Privé du Confluent
City
Nantes
ZIP/Postal Code
44202
Country
France
Individual Site Status
Recruiting
Facility Name
Hospices Civils de Lyon, Hôpital Lyon Sud
City
Pierre-Benite
ZIP/Postal Code
69495
Country
France
Individual Site Status
Recruiting
Facility Name
Centre Armoricain de Radiothérapie, dImagerie Méd
City
Plerin
ZIP/Postal Code
22190
Country
France
Individual Site Status
Recruiting
Facility Name
Centre Eugène Marquis
City
Rennes Cedex
ZIP/Postal Code
35042
Country
France
Individual Site Status
Recruiting
Facility Name
Institut Claudius Regaud - IUCT-O
City
Toulouse
Country
France
Individual Site Status
Recruiting
Facility Name
Institut Gustave Roussy
City
Villejuif
ZIP/Postal Code
94800
Country
France
Individual Site Status
Recruiting
Facility Name
Helios Klinikum Berlin-Buch
City
Berlin
ZIP/Postal Code
13125
Country
Germany
Individual Site Status
Recruiting
Facility Name
: Gynakologisches Zentrum Bonn, Schwerpunkt Gyn. Onkologie,
City
Bonn
ZIP/Postal Code
53111
Country
Germany
Individual Site Status
Recruiting
Facility Name
Marienhospital Bottrop
City
Bottrop
ZIP/Postal Code
46236
Country
Germany
Individual Site Status
Recruiting
Facility Name
Universitätsklinikum Erlangen, Frauen klinik
City
Erlangen
ZIP/Postal Code
91054
Country
Germany
Individual Site Status
Recruiting
Facility Name
Kliniken Essen-Mitte - Evangelische Huyssens-Stift
City
Essen
ZIP/Postal Code
45136
Country
Germany
Individual Site Status
Recruiting
Facility Name
Praxis für interdisziplinäre Onkologie & Hämatolog
City
Freiburg
ZIP/Postal Code
79110
Country
Germany
Individual Site Status
Recruiting
Facility Name
: Universitätsklinikum Hamburg-Eppendorf
City
Hamburg
ZIP/Postal Code
20246
Country
Germany
Individual Site Status
Recruiting
Facility Name
Facharztzentrum Eppendorf
City
Hamburg
ZIP/Postal Code
20249
Country
Germany
Individual Site Status
Recruiting
Facility Name
Nationales Centrum für Tumorerkrankungen
City
Heidelberg
ZIP/Postal Code
69120
Country
Germany
Individual Site Status
Recruiting
Facility Name
Klinik Frauenheilkunde, Uniklinik ClO, Studienzentrale
City
Köln
ZIP/Postal Code
50937
Country
Germany
Individual Site Status
Recruiting
Facility Name
Universitätsklinikum Schleswig-Holstein Institut fur Klinische Chermie
City
Lübeck
ZIP/Postal Code
23538
Country
Germany
Individual Site Status
Recruiting
Facility Name
Universitatsklinikum Mannheim GmBH, Frauenklinik
City
Mannheim
ZIP/Postal Code
68167
Country
Germany
Individual Site Status
Recruiting
Facility Name
Universitätsklinikum Münster, Bereich Senologie an der klinik fur Frauenheilkunde und Gerburtschilfe
City
Munster
ZIP/Postal Code
48149
Country
Germany
Individual Site Status
Recruiting
Facility Name
EV. Krankenhaus Bethesda - Johanniter GmbH, Station 1 Brustzentrum Niederrhein
City
Mönchengladbach
ZIP/Postal Code
41061
Country
Germany
Individual Site Status
Recruiting
Facility Name
Rotkreuzklinikum Munchen Frauenklinik
City
München
ZIP/Postal Code
80637
Country
Germany
Individual Site Status
Recruiting
Facility Name
Klinik und Poliklinik für Frauenheilkunde
City
München
ZIP/Postal Code
81675
Country
Germany
Individual Site Status
Recruiting
Facility Name
Universitatsklinikum Tubingen
City
Tübingen
ZIP/Postal Code
72076
Country
Germany
Individual Site Status
Recruiting
Facility Name
St. Josefs-Hospital Wiesbaden GmbH, Gynakologie und Geburtshilfe
City
Wiesbaden
ZIP/Postal Code
65189
Country
Germany
Individual Site Status
Recruiting
Facility Name
Department of Medicine, Queen Mary Hospital
City
Hong Kong
Country
Hong Kong
Individual Site Status
Recruiting
Facility Name
Hong Kong Sanatorium and Hospital
City
Hong Kong
Country
Hong Kong
Individual Site Status
Recruiting
Facility Name
Tuen Mun Hospital
City
Hong Kong
Country
Hong Kong
Individual Site Status
Recruiting
Facility Name
Prince of Wales Hospital - Hong Kong
City
New Territories
Country
Hong Kong
Individual Site Status
Recruiting
Facility Name
Orszagos Onkologiai Intezet
City
Budapest
ZIP/Postal Code
1122
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Uzsoki Utcai Kórház
City
Budapest
ZIP/Postal Code
1145
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Debreceni Egyetem Klinikai Központ
City
Debrecen
ZIP/Postal Code
4032
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Petz Aladár Egyetemi Oktató Kórház - Gy?r
City
Gyor
ZIP/Postal Code
9024
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Soroka Medical Center
City
Beer-Sheva
ZIP/Postal Code
8410101
Country
Israel
Individual Site Status
Recruiting
Facility Name
Rambam Health Care Campus
City
Haifa
ZIP/Postal Code
3109601
Country
Israel
Individual Site Status
Recruiting
Facility Name
Shaare Zedek Medical Center
City
Jerusalem
ZIP/Postal Code
9103102
Country
Israel
Individual Site Status
Recruiting
Facility Name
Hadassah - Hebrew University Medical Center
City
Jerusalem
Country
Israel
Individual Site Status
Recruiting
Facility Name
Meir Medical Center
City
Kfar Saba
ZIP/Postal Code
4428164
Country
Israel
Individual Site Status
Recruiting
Facility Name
Rabin Medical Center
City
Petah Tikva
ZIP/Postal Code
4941492
Country
Israel
Individual Site Status
Recruiting
Facility Name
Kaplan Medical Center
City
Rehovot
ZIP/Postal Code
7661041
Country
Israel
Individual Site Status
Recruiting
Facility Name
Sheba Medical Center Hospital - Tel Hashomer
City
Tel Aviv
ZIP/Postal Code
52621
Country
Israel
Individual Site Status
Recruiting
Facility Name
Tel Aviv Sourasky Medical Center
City
Tel Aviv
ZIP/Postal Code
64239
Country
Israel
Individual Site Status
Recruiting
Facility Name
IRCCS Istituto Tumori "Giovanni Paolo II"
City
Bari
ZIP/Postal Code
70124
Country
Italy
Individual Site Status
Recruiting
Facility Name
SSD Oncologia Medica Addarii-Zamagni, IRCSS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola
City
Bologna
Country
Italy
Individual Site Status
Recruiting
Facility Name
UO Oncologia, ASST degli Spedali Civili di Brescia
City
Brescia
ZIP/Postal Code
25123
Country
Italy
Individual Site Status
Recruiting
Facility Name
IRCCS Ospedale Policlinico San Martino
City
Genova GE
ZIP/Postal Code
16132
Country
Italy
Individual Site Status
Recruiting
Facility Name
S.C. Oncologia medica, ASST di Lecco
City
Lecco
ZIP/Postal Code
23900
Country
Italy
Individual Site Status
Recruiting
Facility Name
Presidio Ospedaliero di Lucca
City
Lucca
ZIP/Postal Code
55100
Country
Italy
Individual Site Status
Recruiting
Facility Name
Ospedale San Raffaele
City
Milano
ZIP/Postal Code
20132
Country
Italy
Individual Site Status
Recruiting
Facility Name
Fondazione IRCCS - Istituto Nazionale dei Tumori
City
Milano
ZIP/Postal Code
20133
Country
Italy
Individual Site Status
Recruiting
Facility Name
Centro Ricerca Fase I, Fondazione IRCSS San Gerado dei Tintori
City
Monza
ZIP/Postal Code
20090
Country
Italy
Individual Site Status
Recruiting
Facility Name
Oncologia Medica Senologica Sperimentale - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale
City
Napoli
ZIP/Postal Code
80131
Country
Italy
Individual Site Status
Recruiting
Facility Name
AOU Maggiore della Carita
City
Novara
ZIP/Postal Code
28100
Country
Italy
Individual Site Status
Recruiting
Facility Name
Istituto Oncologico Veneto - IRCCS
City
Padova
ZIP/Postal Code
35128
Country
Italy
Individual Site Status
Recruiting
Facility Name
S.O.C Oncologia Medica, Nuovo Ospedale di Prato Santo Stefano
City
Prato
ZIP/Postal Code
59100
Country
Italy
Individual Site Status
Recruiting
Facility Name
Policlinico di Roma
City
Roma
ZIP/Postal Code
00161
Country
Italy
Individual Site Status
Recruiting
Facility Name
Fondazione Policlinico Universitario Agostino Geme
City
Rome
ZIP/Postal Code
00168
Country
Italy
Individual Site Status
Recruiting
Facility Name
Azienda Ospedaliera Universitaria Senese - Losped
City
Siena
ZIP/Postal Code
53100
Country
Italy
Individual Site Status
Recruiting
Facility Name
Aichi Cancer Center Hospital
City
Aichi
ZIP/Postal Code
464-8681
Country
Japan
Individual Site Status
Recruiting
Facility Name
Tohoku University Hospital
City
Aoba-ku
ZIP/Postal Code
980-8574
Country
Japan
Individual Site Status
Recruiting
Facility Name
Juntendo University Hospital
City
Bunkyo-ku
ZIP/Postal Code
113-8431
Country
Japan
Individual Site Status
Recruiting
Facility Name
Chiba Cancer Center
City
Chuo-ku
ZIP/Postal Code
260-8717
Country
Japan
Individual Site Status
Recruiting
Facility Name
Osaka Prefectural Hospital Organization Osaka International Cancer Institute
City
Chuo-ku
ZIP/Postal Code
541-8567
Country
Japan
Individual Site Status
Recruiting
Facility Name
NHO Shikoku Cancer Center
City
Ehime
ZIP/Postal Code
791-0280
Country
Japan
Individual Site Status
Recruiting
Facility Name
Fukushima Medical University Hospital
City
Fukushima
Country
Japan
Individual Site Status
Recruiting
Facility Name
Saitama Cancer Center
City
Inamachi
ZIP/Postal Code
362-0806
Country
Japan
Individual Site Status
Recruiting
Facility Name
Hakuaikai Sagara Hospital
City
Kagoshima-shi
ZIP/Postal Code
892-0833
Country
Japan
Individual Site Status
Recruiting
Facility Name
National Cancer Center Hospital East
City
Kashiwa
ZIP/Postal Code
277-8577
Country
Japan
Individual Site Status
Recruiting
Facility Name
The Cancer Institute Hospital of JFCR
City
Koto-ku
ZIP/Postal Code
135-8550
Country
Japan
Individual Site Status
Recruiting
Facility Name
Kumamoto University Hospital
City
Kumamoto- shi
ZIP/Postal Code
860-8556
Country
Japan
Individual Site Status
Recruiting
Facility Name
Kure Medical Center And Chugoku Cancer Center
City
Kure
ZIP/Postal Code
737-0023
Country
Japan
Individual Site Status
Recruiting
Facility Name
Mie University Hospital
City
Mie
ZIP/Postal Code
514-8507
Country
Japan
Individual Site Status
Recruiting
Facility Name
Nagoya University Hospital
City
Nagoya
ZIP/Postal Code
466-8560
Country
Japan
Individual Site Status
Recruiting
Facility Name
Nagoya City University Hospital
City
Nagoya
ZIP/Postal Code
467-8602
Country
Japan
Individual Site Status
Recruiting
Facility Name
Hiroshima City Hiroshima Citizens Hospital
City
Naka-ku
ZIP/Postal Code
730-8518
Country
Japan
Individual Site Status
Recruiting
Facility Name
NIigata Cancer Center Hospital
City
Niigata-shi
ZIP/Postal Code
951-8566
Country
Japan
Individual Site Status
Recruiting
Facility Name
Okayama University Hospital
City
Okayama
ZIP/Postal Code
700-8558
Country
Japan
Individual Site Status
Recruiting
Facility Name
Gunma Prefectural Cancer Center
City
Ota
ZIP/Postal Code
373-8550
Country
Japan
Individual Site Status
Recruiting
Facility Name
Kyoto University Hospital
City
Sakyo-ku
ZIP/Postal Code
606-8507
Country
Japan
Individual Site Status
Recruiting
Facility Name
Hokkaido Cancer Center
City
Sapporo
ZIP/Postal Code
003-0804
Country
Japan
Individual Site Status
Recruiting
Facility Name
Shizuoka General Hospital
City
Shizuoka-city
ZIP/Postal Code
420-8527
Country
Japan
Individual Site Status
Recruiting
Facility Name
Shizuoka Cancer Center
City
Shizuoka
ZIP/Postal Code
411-8777
Country
Japan
Individual Site Status
Recruiting
Facility Name
Osaka University Hospital
City
Suita
ZIP/Postal Code
565-0871
Country
Japan
Individual Site Status
Recruiting
Facility Name
Showa University Hospital
City
Tokyo
ZIP/Postal Code
142-8555
Country
Japan
Individual Site Status
Recruiting
Facility Name
Kanagawa Cancer Center
City
Yokohama
ZIP/Postal Code
241-8515
Country
Japan
Individual Site Status
Recruiting
Facility Name
National Cancer Center - Korea
City
Goyang-si Gyeonggi-do
ZIP/Postal Code
10408
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Seoul National University Bundang Hospital
City
Seongnam-si
ZIP/Postal Code
13620
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Severance Hospital
City
Seoul
ZIP/Postal Code
03722
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Asan Medical Center
City
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Samsung Medical Center
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Korea University Anam Hospital
City
Seoul
ZIP/Postal Code
2841
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Seoul National University Hospital
City
Seoul
ZIP/Postal Code
3080
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
The Catholic University of Korea, Seoul St. Mary's Hospital
City
Seoul
ZIP/Postal Code
6591
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Icaro Investigaciones en Medicina S.A. de C.V.
City
Chihuahua
ZIP/Postal Code
31000
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Cryptex Investigación Clínica
City
Ciudad de Mexico
ZIP/Postal Code
06100
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Centro para el Desarrollo de la Medicina
City
Culiacan
ZIP/Postal Code
80230
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Panamerican Clinical Research Mexico - Guadalajara
City
Guadalajara
ZIP/Postal Code
44670
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Medical Care and Research S.A. de C.V
City
Merida
ZIP/Postal Code
97070
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Avix Investigacion Clinica S.C.
City
Monterrey
ZIP/Postal Code
64710
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Fucam A.C.
City
México
ZIP/Postal Code
4980
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Oncológico Potosino
City
San Luis Potosi
ZIP/Postal Code
78209
Country
Mexico
Individual Site Status
Recruiting
Facility Name
FAICIC Clínical Research
City
Veracruz
ZIP/Postal Code
91900
Country
Mexico
Individual Site Status
Recruiting
Facility Name
iBiomed - Investigacion Biomedica para el Desarrol
City
Zapopan
ZIP/Postal Code
45070
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Amphia Ziekenhuis - Breda Langendijk
City
Breda
ZIP/Postal Code
4818 CK
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Universitair Medisch Centrum Groningen
City
Groningen
ZIP/Postal Code
9700 RB
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Medisch Centrum Leeuwarden
City
Leeuwarden
ZIP/Postal Code
8934 AD
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Erasmus Medisch Centrum
City
Rotterdam
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Narodowy Instytut Onkologii im. Marii Sklodowskiej
City
Gliwice
ZIP/Postal Code
44-102
Country
Poland
Individual Site Status
Recruiting
Facility Name
SP ZOZ Opolskie Centrum Onkologii im. prof. Tadeusza Koszarowskiego
City
Opole
ZIP/Postal Code
45-061
Country
Poland
Individual Site Status
Recruiting
Facility Name
Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-Curie
City
Poznan
ZIP/Postal Code
61- 866
Country
Poland
Individual Site Status
Recruiting
Facility Name
Mazowiecki Szpital Wojewódzki im. w. Jana Pawa II w
City
Siedlce
ZIP/Postal Code
08-110
Country
Poland
Individual Site Status
Recruiting
Facility Name
Wojskowy Instytut Medyczny
City
Warsaw
ZIP/Postal Code
04-141
Country
Poland
Individual Site Status
Recruiting
Facility Name
Narodowy Instytut Onkologii im.Marii Marii Sklodowskiejs
City
Warszawa
ZIP/Postal Code
02-781
Country
Poland
Individual Site Status
Recruiting
Facility Name
Ponce Medical School Foundation Inc.
City
Ponce
ZIP/Postal Code
00716
Country
Puerto Rico
Individual Site Status
Recruiting
Facility Name
Clinical Research Puerto Rico
City
San Juan
ZIP/Postal Code
00909-1711
Country
Puerto Rico
Individual Site Status
Recruiting
Facility Name
Hopelands Cancer Centre
City
Hilton
ZIP/Postal Code
3245
Country
South Africa
Individual Site Status
Recruiting
Facility Name
The Medical Oncology Centre of Rosebank
City
Johannesburg
ZIP/Postal Code
2196
Country
South Africa
Individual Site Status
Recruiting
Facility Name
University of Pretoria
City
Pretoria
ZIP/Postal Code
0002
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Hospital Teresa Herrera - Materno Infantil
City
A Coruña
ZIP/Postal Code
15006
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitari Dexeus
City
Barcelona
ZIP/Postal Code
08028
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Clinic Barcelona
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital de la Santa Creu i Sant Pau
City
Barcelona
ZIP/Postal Code
8023
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitari Vall d'Hebrón
City
Barcelona
ZIP/Postal Code
8035
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario de Basurto
City
Bilbo
ZIP/Postal Code
48013
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitari Arnau de Vilanova
City
Lleida
ZIP/Postal Code
25198
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital General Universitario Gregorio Marañón
City
Madrid
ZIP/Postal Code
28007
Country
Spain
Individual Site Status
Recruiting
Facility Name
MD Anderson Cancer Centre Madrid
City
Madrid
ZIP/Postal Code
28033
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Fundación Jiménez Díaz
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Virgen de la Victoria
City
Malaga
ZIP/Postal Code
29010
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital General Universitario Morales Meseguer
City
Murcia
ZIP/Postal Code
30008
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Unviersitario Virgen del Rocio
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Virgen Macarena
City
Sevilla
ZIP/Postal Code
41071
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario de Canarias
City
Tenerife
ZIP/Postal Code
38320
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Clínico Universitario de Valencia
City
Valencia
ZIP/Postal Code
46010
Country
Spain
Individual Site Status
Recruiting
Facility Name
Kantonsspital Baden
City
Baden
ZIP/Postal Code
5404
Country
Switzerland
Individual Site Status
Recruiting
Facility Name
Kantonsspital Baselland - Standort Liestal
City
Liestal
ZIP/Postal Code
4410
Country
Switzerland
Individual Site Status
Recruiting
Facility Name
Kantonsspital Sankt Gallen
City
St. Gallen
ZIP/Postal Code
9007
Country
Switzerland
Individual Site Status
Recruiting
Facility Name
Kantonsspital Winterthur
City
Winterthur
ZIP/Postal Code
8401
Country
Switzerland
Individual Site Status
Recruiting
Facility Name
Brust-Zentrum Zurich
City
Zürich
ZIP/Postal Code
8008
Country
Switzerland
Individual Site Status
Recruiting
Facility Name
Changhua Christian Hospital
City
Changhua
ZIP/Postal Code
50006
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Kaohsiung Medical University Chung-Ho Memorial Hospital
City
Kaohsiung
ZIP/Postal Code
807
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Taipei Medical University-Shuang Ho Hospital
City
New Taipei City
ZIP/Postal Code
235
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
National Cheng Kung University Hospital
City
Tainan
ZIP/Postal Code
704
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Taipei Veterans General Hospital
City
Taipei City
ZIP/Postal Code
11217
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
National Taiwan University Hospital
City
Taipei
ZIP/Postal Code
100
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Linkou Chang Gung Memorial Hospital
City
Taoyuan
ZIP/Postal Code
333
Country
Taiwan
Individual Site Status
Recruiting
Facility Name
Baskent Uni. Dr Turgut Noyan Uyg. ve Aras. Merkezi
City
Adana
ZIP/Postal Code
1120
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve A
City
Ankara
ZIP/Postal Code
6010
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
City
Ankara
ZIP/Postal Code
6200
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Memorial Ankara Hastanesi
City
Ankara
ZIP/Postal Code
6520
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Hacettepe Üniversitesi Hastanesi
City
Ankara
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Trakya Universitesi Tip Fakultesi Hastanesi
City
Edirne
ZIP/Postal Code
22030
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Istanbul Il Saglik Mudurlugu Goztepe Prof. Dr. Sul
City
Istanbul
ZIP/Postal Code
34000
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Medipol Mega Universite Hastanesi
City
Istanbul
ZIP/Postal Code
34214
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Medicana International Izmir Hastanesi
City
İzmir
ZIP/Postal Code
35575
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Acibadem Maslak Hastanesi
City
Sariyer
Country
Turkey
Individual Site Status
Recruiting
Facility Name
NHS Lothian
City
Edinburgh
ZIP/Postal Code
EH4 2XU
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Clinical Trials Unit Lvl 0 Cancer Research UK Beatson Institute
City
Glasgow
ZIP/Postal Code
G12 0YN
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Leeds Teaching Hospitals NHS Trust
City
Leeds
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
: Barts Health NHS Trust, St Hospital
City
London
ZIP/Postal Code
EC1M 6BQ
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Guy's and Saint Thomas' NHS Foundation Trust
City
London
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
University College London Hospitals
City
London
ZIP/Postal Code
WC1E 6BT
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Nottingham University Hospitals NHS Trust
City
Nottingham
ZIP/Postal Code
NG5 1PB
Country
United Kingdom
Individual Site Status
Recruiting
12. IPD Sharing Statement
Plan to Share IPD
No
Links:
URL
https://www.gileadclinicaltrials.com/study/?id=GS-US-592-6173
Description
Gilead Clinical Trials Website
Learn more about this trial
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
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