Study on the Correlation Between the Quantitative Parameters of Mr Mean Cell Size Imaging and the Histopathological Characteristics of Breast Cancer (OGSE)
Breast Carcinoma; Magnetic Resonance Imaging;OGSE
About this trial
This is an interventional diagnostic trial for Breast Carcinoma; Magnetic Resonance Imaging;OGSE
Eligibility Criteria
Inclusion Criteria:
- Breast cancer was confirmed by operation or biopsy;
- The status of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor-2 (HER-2), Ki-67 and lymphatic vessel invasion (LVI) in breast cancer were clearly diagnosed by pathology;
- Routine MRI and mean cell size imaging sequence scanning were performed within 1 week before pathological examination
Exclusion Criteria:
(1) Breast cancer patients who had received treatment before mean cell size imaging sequence scanning; (2) Patients who had undergone breast tumor puncture within 2 weeks before the mean cell size imaging sequence scan; (3) Patients with breast masses without surgery or biopsy after mean cell size imaging sequence scanning; (4) The breast mass was confirmed to be other diseases except breast cancer by pathological examination; (5) The image quality is poor due to motion artifacts or other reasons, so the average cell size imaging post-processing cannot be carried out.
Sites / Locations
- Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Arms of the Study
Arm 1
Experimental
Gradient and pulse imaging
All subjects used standardized breast MRI scanning schemes, including T2 weighted imaging (T2WI), T1 weighted imaging (T1WI), diffusion weighted imaging (DWI), PGSE, OGSE and contrast dynamic enhancement (DCE). Three quantitative parameters of VIN, DEX and D are derived on MATLAB software