Study to Evaluate Cardiac Hemodynamics and Safety of SLV320 in Subjects With Congestive Heart Failure
Congestive Heart Failure
About this trial
This is an interventional treatment trial for Congestive Heart Failure focused on measuring congestive heart failure, adenosine receptor blocker, cardiac hemodynamic
Eligibility Criteria
Inclusion Criteria: history of chronic, symptomatic, mild to severe (NYHA Class II-IV) CHF for at least three months requiring treatment with diuretics and with documented systolic dysfunction on stable doses of their individually optimized medication regimen for at least one week prior to enrollment Exclusion Criteria: required hospitalization (for cardiovascular disease) or adjustment of background medications for CHF orthostatic hypotension or symptomatic orthostasis sitting systolic or diastolic blood pressure < 90 mmHg 2nd or 3rd degree atrio-ventricular block or sick sinus syndrome heart rate of < 50 or > 110 bpm on the ECG transplanted heart heart failure due to primary valvular disease (unless surgically corrected), obstructive cardiomyopathy, pericardial disease, cor pulmonale or congenital heart disease hemodynamically significant left ventricular outflow tract obstruction
Sites / Locations
- Site 1