Subthalamic Deep Brain Stimulation (DBS) in Parkinson's Disease
Parkinson's Disease
About this trial
This is an interventional other trial for Parkinson's Disease focused on measuring parkinson, PD, parkinson disease, parkinson's, parkinson's disease, parkinsons, parkinsons disease, TMS, DBS, transcranial magnetic stimulation, deep brain stimulation
Eligibility Criteria
Inclusion Criteria:
- Aged 18-80 years
- Diagnosis of Parkinson's Disease with bilateral subthalamic nucleus (STN) DBS
Exclusion Criteria:
- Cardiac pacemakers
- Need for diathermy
- Repeat MRI scanning
- Anticoagulant therapy
- Previous neuro surgical procedure or ablative therapy
- Frank dementia according to cognitive screening
- History of seizures
- Pregnancy
- Presence of a terminal illness
Sites / Locations
- University of Florida
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
People with Parkinsons Disease
Healthy Controls
Participants have been diagnosed with Parkinson's Disease, and as recommended by their physicians, have undergone DBS surgery for both sides of the brain. These participants will undergo TMS and motor physiology testing, and results will be compared to participants without Parkinson's Disease.
These participants do not have Parkinson's Disease, nor have they had DBS surgery, and are a healthy controls. These participants will undergo TMS and motor physiology testing, and results will be compared to participants with Parkinson's Disease.