Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Healthy, Mild Cognitive Impairment, Alzheimer Disease
About this trial
This is an interventional basic science trial for Healthy
Eligibility Criteria
Inclusion Criteria:
- Written informed consent
- Right-handedness
- Non-smokers
- Native German speakers or comparable level of fluency
- Normal or corrected-to-normal vision
Exclusion Criteria:
- Neurological or psychiatric condition (other than diagnosed cognitive impairment)
- Past head injuries
- Magnetizable implants
- History of seizures
- Current or life-time alcohol or drug abuse
- Pregnancy
- Skin diseases
Sites / Locations
- University Hospital of Old Age Psychiatry and Psychotherapy
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Real - sham anodal tDCS
Sham - real anodal tDCS
Session 1: 20 min of 1 mA anodal tDCS applied via 5x7 cm rubber electrodes over the DLPFC (current density: 0.028 mA/cm2). Additional ramp-up and ramp-down phase at beginning and end of stimulation lasting for 15 s. Electrodes remain attached to the participant's head for the duration of the encoding phase. Session 2: 30 s of 1 mA anodal tDCS applied via 5x7 cm rubber electrodes over the DLPFC (current density: 0.028 mA/cm2). Additional ramp-up and ramp-down phase at beginning and end of stimulation lasting for 15 s. Electrodes remain attached to the participant's head for the duration of the encoding phase.
Session 1: 30 s of 1 mA anodal tDCS applied via 5x7 cm rubber electrodes over the DLPFC (current density: 0.028 mA/cm2). Additional ramp-up and ramp-down phase at beginning and end of stimulation lasting for 15 s. Electrodes remain attached to the participant's head for the duration of the encoding phase. Session 2: 20 min of 1 mA anodal tDCS applied via 5x7 cm rubber electrodes over the DLPFC (current density: 0.028 mA/cm2). Additional ramp-up and ramp-down phase at beginning and end of stimulation lasting for 15 s. Electrodes remain attached to the participant's head for the duration of the encoding phase.