Systematic Light Exposure in Pediatric Brain Tumor Survivors (SLEPBT)
Brain Tumor
About this trial
This is an interventional supportive care trial for Brain Tumor focused on measuring Pediatric Oncology, Fatigue, Cognitive Late Effects, Light Exposure, Sleep, Mood, Brain Tumor
Eligibility Criteria
Inclusion Criteria:
- Diagnosed and treated for a brain tumor at Texas Children's Hospital
- Treated with either surgery only or surgery and proton beam radiation therapy
- Treated for tumors other than high-grade gliomas, brain stem gliomas, or atypical teratoid rhabdoid tumors given associated reduced survival rates
- Enrolled on/in existing longitudinal studies of neurocognitive outcomes in survivors of pediatric brain tumor (Lisa Kahalley, PI; H-29026, H-35681, H-40804, H-40961, H-50648)
- Ages 10-18 years
- At least 3 years post-diagnosis
- Endorsed mild to moderate symptoms of fatigue on the PROMIS
- Approval from Long-Term Survivorship provider
- Adequate vision for computerized tasks
- English-speaking
- Intelligence Quotient (IQ) above 70
Exclusion Criteria:
- Diagnosis and/or treatment for secondary malignancy in the past 12 months
- Current or previous (within 12 months) suicidal ideation or severe depression requiring immediate intervention
- Presence of photophobia or other eye diseases, seizures, and/or migraines
- Use of photosensitizing medications
- Current or previous use of light therapy
Sites / Locations
- Texas Children's HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Bright Light Exposure
Dim Light Exposure
Participants are exposed to bright light (1,000 lux at eye level) using light glasses (Luminette Version 3) for a maximum duration of 30 minutes upon awakening each day from Monday to Friday for 6 weeks while wearing an actigraph and periodic completion of questionnaires, cognitive assessments, and lab work.
Participants are exposed to exposed to dim light (equivalent intensity of <25 lux) using light glasses (Luminette) for a maximum duration of 30 minutes upon awakening each day from Monday to Friday for 6 weeks while wearing an actigraph and periodic completion of questionnaires, cognitive assessments, and lab work.