Targeted Evaluation, Action, & Monitoring of Traumatic Brain Injury (TEAM-TBI)

TEAM-TBI (Targeted Evaluation, Action, and Monitoring of Traumatic Brain Injury) is a research study that brings together TBI patients, advanced evaluation methods, and experts in a multi-faceted study to address the heterogeneity of TBI and to evaluate the effects self-help strategies might have on TBI outcomes.

TEAM-TBI (Targeted Evaluation, Action, and Monitoring of Traumatic Brain Injury) proposes a new approach to clinical trials in TBI that will: Evolve diagnostic technology & treatment Improve self-help strategies Lower cost and speed for delivery of effective strategies The TEAM-TBI program proposes an innovative new approach to TBI clinical trials to overcome the limitations of past efforts and achieve long-awaited breakthroughs for TBI survivors. The study will involve a comprehensive 3-4 day intake evaluation, followed by a variety of remotely performed tasks during a 1-6 month follow-up period.

All participants have a history of TBI. At study outcome participants are provided treatment recommendations that are the result of a consensus meeting of all physician investigators. Follow up care is not provided by this clinical trial.

These tests will be used to determine how the participant will continue with future procedures, and depending on results, may involve the participant returning to complete subsequent testing.

These assessments will involve a series of tests and questionnaires that focus on physical symptoms of TBI and will include dizziness, balance, ocular-motor coordination, and reflexes.

These assessments will involve a series of tests and questionnaires that focus on physical symptoms of TBI including neck mobility and pain levels.

These evaluations will focus on assessing insomnia (duration, frequency, daytime consequences), combat exposure, and the presence and severity of trauma history.

This MRI aims at providing qualitative and quantitative assessments of the nature, location, and extent of white matter injury.

This is a non-invasive neurophysiological technique that measures the magnetic fields generated by neuronal activity of the brain.

The main outcome variable in the study will be the change in Post-Concussion Symptom Scale (PCSS) score from the initial intake evaluation compared to last follow-up evaluation.

Inclusion Criteria: 18-60 years of age Fluent in English Documented history of TBI or blast exposure since 2001 Exclusion Criteria: Inability to have MRI Pregnancy History of TIA within last 6 months. Presently involved in open litigation