Telomeres Parameters in Celiac Disease
Primary Purpose
Celiac Disease
Status
Unknown status
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
take blood samples
Sponsored by
About this trial
This is an interventional basic science trial for Celiac Disease focused on measuring celiac, telomere, telomerase
Eligibility Criteria
Inclusion Criteria:
- patients with celiac disease
Exclusion Criteria:
- known malignancy
- cannot sign informed consent
- under age 18
Sites / Locations
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
celiac disease
Arm Description
Outcomes
Primary Outcome Measures
telomere length
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT02126033
Brief Title
Telomeres Parameters in Celiac Disease
Study Type
Interventional
2. Study Status
Record Verification Date
April 2014
Overall Recruitment Status
Unknown status
Study Start Date
undefined (undefined)
Primary Completion Date
December 2015 (Anticipated)
Study Completion Date
undefined (undefined)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Meir Medical Center
4. Oversight
5. Study Description
Brief Summary
Celiac disease is an autoimmune process that causes destructive changes in the epithel of the small bowel and it is also a pre-malignant state (e.g lymphoma). The aim of the study is to examine telomere length and other parameters of genetic instability from peripheral blood lymphocytes of patients with celiac disease compared with healthy controls.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Celiac Disease
Keywords
celiac, telomere, telomerase
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Enrollment
40 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
celiac disease
Arm Type
Experimental
Intervention Type
Procedure
Intervention Name(s)
take blood samples
Primary Outcome Measure Information:
Title
telomere length
Time Frame
at entry, after 6 months of gluten-free diet
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
patients with celiac disease
Exclusion Criteria:
known malignancy
cannot sign informed consent
under age 18
12. IPD Sharing Statement
Learn more about this trial
Telomeres Parameters in Celiac Disease
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