The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT
Depressive Disorder
About this trial
This is an interventional treatment trial for Depressive Disorder focused on measuring Depressive disorder,, Antidepressant effect,, rTMS,, ECT,, cognition,, Saliva cortisol, noninferiority trial
Eligibility Criteria
Inclusion Criteria Admission to Psychiatric Hospital in Aarhus. The patient should be candidate for ECT. Moderate or severely depressed/Major depressed (ICD-10/DSM-IV) A total score on the Hamilton (17-item) rating scale for depression of 20 or above, or a subscale score of 10 ore above. Right handed, Age 18-80 years Exclusion Criteria: Organic brain disease Epilepsy Metal devices in operated into the brain or chest. The patient is wearing cardiac pacemaker. Medical illness associated with disturbed CNS function Pregnancy Serious suicidality Severe agitation or delirium Alcoholic or drug dependency The patients exposed to coercive measures
Sites / Locations
- University hospital of Aarhus, Risskov
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
1
2
Right frontal low frequency rTMS
electroconvulsive therapy (ECT). Right unilateral ECT 3 time a week in 3 weeks