The Application of Cognitive Rehabilitation Therapy for Amphetamine-type Stimulants Addiction
Amphetamine Addiction
About this trial
This is an interventional treatment trial for Amphetamine Addiction focused on measuring Amphetamine-type stimulants, prefrontal-striatal circuits, cognitive rehabilitation therapy
Eligibility Criteria
Inclusion Criteria:
- diagnosed MA dependence in accordance with the fourth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) (Association, 2000);
- more than 9 years of education;
- aged of 18-60 years old;
- normal vision, audition and no color blindness;
- receive no detoxification medications during treatment and
- right handedness.
Exclusion Criteria:
- current medical diseases that required hospitalization or regular monitoring;
- serious physical or neurological illness that required pharmacological treatment affecting cognitive function;
- history of major psychiatric disorder such as bipolar disorder, schizophrenia, depression and disorders of high comorbidity with substance abuse/dependence;
- neurological diseases such as stroke, seizure, migraine, head trauma
- substance dependence other than nicotine, within the past 5 years;
- intelligence quotient (IQ) <70.
Sites / Locations
- Shanghai Compulsory Isolation Detoxification Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
No Intervention
cognitive function rehabilitation group
cognitive bias modification group
control group
The main content of cognitive function rehabilitation esecutive function,including working memory,sustained attention, response inhibition function and cognitive flexibility, 45 minutes a day over 6 weeks period.
The main content of cognitive bias modification groups were changing ATS related attention bias, 45 minutes a day over 6 weeks period.
Participants only accept the regular scheduled in the compulsory isolated detoxification center