The (Cost)Effectiveness of Increasing Protein Intake on Physical Funtioning in Older Adults
Protein-Energy Malnutrition, Physical Disability
About this trial
This is an interventional prevention trial for Protein-Energy Malnutrition
Eligibility Criteria
Inclusion criteria:
- Age ≥ 65 years;
- Community-dwelling;
- Lower protein intake defined as both a probability score above a certain cutoff on the protein screener (www.proteinscreener.nl) as well as based on actual protein intake assessed by 24-hour recalls. The protein screener was developed and validated using an extended FFQ among Dutch older adults. The cutoff will be chosen based on results of different studies in which the investigators compare the probability scores of the protein screener with protein intake as measured with food diaries and/or dietary recalls. The investigators will then choose the probability score that is most closely associated with a protein intake < 1.0 g/kg adjusted body weight/day. This probably score reflects older adults with a higher probability on a protein intake < 1.0 g/kg adjusted body weight/d than a general sample of older adults;
Exclusion criteria:
- Inability or unwillingness to provide informed consent
- Not able to eat independently;
- Not able to speak, write and read the Dutch language;
- Current participation to supervised behavioral or lifestyle intervention that intervenes with PROMISS intervention;
- Not able the visit the research site in the following next 6 months;
- Bedridden or wheelchair bound;
- Individuals who do not go outside;
- Diagnosed with severe kidney disease;
- Diagnosed with Parkinson's disease;
- Diagnosed with diabetes mellitus type I;
- Diagnosed with diabetes mellitus type 2 and starting with insulin;
- Current treatment of cancer (with the exception of basal cell carcinoma);
- Vegan diet;
- Severe allergies to certain food products (such as peanuts, gluten);
- Diagnosed with an eating disorder (self-reported);
- Purposefully lost/gained > 3 kg in the past three months
- Heart problems in the past three months (heart attack, angioplasty, heart surgery, stroke or other serious heart disease)
- Not able to complete the 400 meter walk test within 15 minutes (self-reported, and assessed at study baseline).
- Alcohol abuse past 6 months (AUDIT-C ≥ 2);
- Low cognitive status, defined as the mini-mental state examination (MMSE) score ≤ 20
- BMI < 18.5 kg/m2 (self-reported, and assessed at study baseline);
- Overweight, defined as BMI > 32.0 kg/m2 (self-reported, and assessed at study baseline);
Sites / Locations
- University of Helsinki
- Vrije Universiteit Amsterdam
Arms of the Study
Arm 1
Arm 2
Arm 3
No Intervention
Experimental
Experimental
Control group
Dietary advice
Dietary advice and advice on timing
No intervention. Participants will only receive a brochure on general healthy eating habits.
Personalized nutritional advice from a registered dietician or nutritionist aimed at increasing protein intake to at least 1.2 g/kg adjusted body weight/d, through intake of regular protein rich food products and provided protein-enriched food products.
Personalized nutritional advice from a registered dietician or nutritionist aimed at increasing protein intake to at least 1.2 g/kg adjusted body weight/d, through intake of regular protein rich food products and provided protein-enriched food products, as well as advice regarding the consumption of protein rich food products in close proximity of usual physical activity.