The Application of a Fasting- Mimicking Diet in Periodontitis: A Feasibility Study
Periodontitis
About this trial
This is an interventional treatment trial for Periodontitis focused on measuring non surgical treatment, fast-mimicking diet, systemic response, gingival crevicular fluid
Eligibility Criteria
Inclusion Criteria: 18-70 years old patients Periodontitis stage III-IV, grade B-C Systemically healthy Normal weight to overweight. Body mass index: 18-30 Minimum of 24 teeth present Be willing and physically able to carry out all study procedures. Absence of hopeless teeth, acute dental conditions, teeth with endo-periodontal lesions and necrotising periodontal diseases. Exclusion Criteria: Age> 70 years old Smokers Systemically compromised Underweight/Obese Pregnant Alcoholism Systemic antibiotics intake within 3 months Periodontal treatment in the last 12 months Mental illness, depression, dementia. Denture wearer/ presence of dental implants Unable or unwilling to participate in baseline or follow up examinations Unable or unwilling to complete the dietary intervention Significant food allergies
Sites / Locations
- Akdeniz University Faculty of DentistryRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Fast mimicking diet group
Normal diet group
The patients in this group will be assigned to follow one cycle of a fasting mimicking diet (FMD) the same day after receiving the full-mouth non-surgical periodontal treatment.
The patients in this group will be assigned to normal diet after receiving the full-mouth non-surgical periodontal treatment.