The Effect of Probiotics on Chronic Kidney Disease
Chronic Kidney Disease, Probiotics, Renal Function
About this trial
This is an interventional treatment trial for Chronic Kidney Disease
Eligibility Criteria
Healthy volunteers:
The criteria for healthy volunteers were: no hypertension (Blood pressure<140/90mmHg), no diabetes (Glucose AC 70~100mg/dl), no hyperlipidemia (Cholesterol Total 130~200mg/dL、Triglyceride<150mg/dL), no urinary protein (-) and normal renal function (eGFR>90), after signing the consent form, the stool samples will be collected.
CKD patients:
Inclusion Criteria:
‧Stage 3-5 CKD patients, at least 20 years of age and regular follow-up for at least 6 months prior to enrollment.
Exclusion Criteria:
- Pregnancy.
- On immunosuppressive therapy.
- Active infectious condition.
- Acute kidney injury.
- Consuming other forms of probiotics.
- Taking antibiotics within 30 days prior to enrollment.
Sites / Locations
- China Medical University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Probiotics
Healthy control
Taking two capsules of probiotics twice daily for 12 months.
Healthy volunteers were: no hypertension (Blood pressure<140/90mmHg), no diabetes (Glucose AC 70~100mg/dl), no hyperlipidemia (Cholesterol Total 130~200mg/dL、Triglyceride<150mg/dL), no urinary protein (-) and normal renal function (eGFR>90), after signing the consent form, the stool samples will be collected.