The Effect of Weight Loss and Exercise on Knee Osteoarthritis
Osteoarthritis, Knee
About this trial
This is an interventional treatment trial for Osteoarthritis, Knee focused on measuring Osteoarthritis, Arthritis, Weight Loss
Eligibility Criteria
Inclusion Criteria Knee arthritis Pain on > 50 % of days in the month in one or both knees Difficulty with activities of daily living due to knee pain X-ray documenting knee OA within 1 year prior to study entry 15 lbs to 50 lbs overweight Exclusion Criteria Significant cardiac, pulmonary, renal, or hepatic disease Major psychiatric disease ACR functional class IV Structured exercise more than once per week for 20 minutes or longer during the 3 months prior to study entry Anticipates moving from the area within 18 months of study entry Anticipates undergoing knee surgery within 1 year of study entry Weight loss of more than 5 kg (11 lbs) in 3 months prior to study entry Anorexiant or other medications known to affect metabolism Current or planned pregnancy
Sites / Locations
- Johns Hopkins Bayview Medical Center
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
1
2
16 weekly educational meetings
Wait list control