The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3
Cocaine Abuse, Cocaine-Related Disorders
About this trial
This is an interventional treatment trial for Cocaine Abuse focused on measuring addiction, crack, cocaine
Eligibility Criteria
Inclusion Criteria: Meets DSM-IV criteria for cocaine dependence History of smoked or intravenous cocaine use on average of at least once a week over a 6 month period Positive urine test for cocaine No current medical problems Normal electrocardiogram If female, willing to use contraception throughout the study Exclusion Criteria: Seeking treatment for cocaine dependence Current major psychiatric illness, including mood disorder, psychotic disorder, or anxiety disorder Current dependence on alcohol or any drugs other than cocaine or nicotine History of major medical illness, including liver disease, suspected or known cancer, thrombophlebitis, or other medical conditions that are considered unsafe for study participants by the investigator Known allergy to study medications Pregnant or breastfeeding
Sites / Locations
- VA Connecticut Healthcare System
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
pregabalin
Placebo
pregabalin compared to placebo
Placebo compared to pregabalin