The Effects of Low Energy Availability and High Impact Jumping on Markers of Bone (re)Modelling in Females
Bone Resorption, Bone Atrophy, Energy Supply; Deficiency
About this trial
This is an interventional prevention trial for Bone Resorption focused on measuring Low energy availability, Energy restriction, Bone (re)modelling, Bone metabolism, High impact exercise
Eligibility Criteria
To take part in this study, the following inclusion criteria must be met:
- Menstrual cycles that are between 21 - 35 days in length for at least the previous three cycles
- Regular length of menstrual cycle (less than six days difference between cycles) for at least the previous three cycles
- Body mass index between 18.5 - 30 kg.m squared
- Weight stable for the past three months and not currently dieting
Participants will not be able to take part in this study if any of the following exclusion criteria are met:
- Smoker
- Pregnant
- Vegan
- Have used hormonal contraception at any point within the previous three months
- Regularly engage in >3 vigorous, or >5 moderate, exercise sessions a week
- Compete regularly in a high or multi-directional impact sport at national level or higher
- Have sustained a bone injury within the previous twelve months
- Have sustained any injury within the past six months that restricted their ability to exercise
- Taken hormone replacement therapy (HRT) at any point during the past three months
- Have been previously diagnosed with an eating disorder
- Have taken any medications (other than vitamin or mineral supplements) known to effect bone metabolism within the previous three months (e.g. glucocorticoids, anticonvulsants or anabolic steroids)
- Have previously been diagnosed with a medical condition known to impact bone health (e.g. hypothyroidism, hyperthyroidism, diabetes mellitus, hypercortisolism and renal or gastrointestinal disease)
- Have previously been diagnosed with a pathology known to impact menstrual function (e.g. primary ovarian insufficiency, hyperprolactinemia, thyroid dysfunction, polycystic ovarian syndrome and any other conditions of androgen excess)
Sites / Locations
- Mark Hutson
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Low energy availability
Low energy availability and high impact jumping
Intervention involves three of dietary energy restriction providing 15 kilo-calories per kilogram of fat-free mass per day.
Intervention involves three days of dietary energy restriction providing 15 kilo-calories per kilogram of fat-free mass per day and brief high impact jumping exercise performed daily in the morning and in the evening.