The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence
Alcoholism, Sleep Initiation and Maintenance Disorders
About this trial
This is an interventional treatment trial for Alcoholism focused on measuring Alcoholism, Insomnia, Quetiapine, Seroquel
Eligibility Criteria
Inclusion Criteria: subjects between the ages of 18-65 years, with a DSM-IV diagnosis of current alcohol dependence (past year), can speak, understand, and print in English, and is capable of giving written informed consent
Exclusion Criteria: Positive urine drug screen for opioids, cocaine, or amphetamine (excluding THC), dependence on other drugs excluding alcohol/nicotine/cannabis over the past year, unstable psychiatric, medical disorders, cataracts [posterior capsular/ nuclear (grade NS3 or more), currently on any maintenance psychotropic medications affecting sleep, currently pregnant, nursing, or not using a reliable method of contraception; history of hypersensitivity to antipsychotic drugs, including quetiapine, severe cognitive impairment, severe untreated obstructive sleep apnea, and inadequately controlled diabetes mellitus.
Sites / Locations
- Philadelphia, OPC
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
1
2
Quetiapine XR
Placebo