Back to resultsThe Effects of Secondary Smoking During One Lung Ventilation
Primary Purpose
Smoking, Oxygen Deficiencies
Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
One Lung Ventilation
Sponsored by
About this trial
This is an interventional other trial for Smoking focused on measuring secondary smoking, one lung ventilation, arterial oxygen tension, lobectomy
Eligibility Criteria
Inclusion Criteria:
- Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.
Exclusion Criteria:
- Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Active Comparator
Arm Label
Group S (non smoking and secondary smoking)
Group SS (secondary smoking)
Arm Description
I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
Outcomes
Primary Outcome Measures
arterial oxygen tension
arterial carbon dioxide tension
intraoperative peak airway pressure
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT03006224
Brief Title
The Effects of Secondary Smoking During One Lung Ventilation
Official Title
The Effects of Secondary Smoking to Intraoperative Arterial Oxygen Tension During One Lung Ventilation in Lobectomy
Study Type
Interventional
2. Study Status
Record Verification Date
April 2017
Overall Recruitment Status
Completed
Study Start Date
December 2016 (Actual)
Primary Completion Date
February 2017 (Actual)
Study Completion Date
April 4, 2017 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Inonu University
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.
Detailed Description
Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Smoking, Oxygen Deficiencies
Keywords
secondary smoking, one lung ventilation, arterial oxygen tension, lobectomy
7. Study Design
Primary Purpose
Other
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Investigator
Allocation
Randomized
Enrollment
60 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Group S (non smoking and secondary smoking)
Arm Type
Active Comparator
Arm Description
I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
Arm Title
Group SS (secondary smoking)
Arm Type
Active Comparator
Arm Description
I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
Intervention Type
Other
Intervention Name(s)
One Lung Ventilation
Primary Outcome Measure Information:
Title
arterial oxygen tension
Time Frame
From beginning of Anesthesia to 1st day of surgery
Title
arterial carbon dioxide tension
Time Frame
From beginning of Anesthesia to 1st day of surgery
Title
intraoperative peak airway pressure
Time Frame
during intraoperative ventilation
10. Eligibility
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.
Exclusion Criteria:
Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.
12. IPD Sharing Statement
Plan to Share IPD
Undecided
Learn more about this trial
The Effects of Secondary Smoking During One Lung Ventilation
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