search
Back to results

The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise

Primary Purpose

Sleep Deprivation

Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Sleep deprivation
Sponsored by
St Mary's University College
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Sleep Deprivation

Eligibility Criteria

18 Years - 45 Years (Adult)MaleAccepts Healthy Volunteers

Inclusion Criteria:

  • Injury-free, trained, male runners

Exclusion Criteria:

  • Female, untrained, injured

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Experimental

    No Intervention

    Arm Label

    Sleep deprivation

    No intervention

    Arm Description

    Two hours of sleep deprivation (Six hours of sleep)

    No sleep deprivation (Eight hours of sleep)

    Outcomes

    Primary Outcome Measures

    Oxygen uptake
    Change from baseline in oxygen uptake measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Respiratory exchange ratio
    Change from baseline in respiratory exchange ratio measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Breathing frequency
    Change from baseline in breathing frequency measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Minute ventilation
    Change from baseline in minute ventilation measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Blood lactate concentration
    Change from baseline in blood lactate concentration measured using capillary puncture during submaximal and maximal incremental exercise
    Rating of perceived exertion
    Change from baseline in ratings of perceived exertion measured using a 15-point (6-20) scale during submaximal and maximal incremental exercise
    Heart rate
    Change from baseline in heart rate measured using a heart rate monitor during submaximal and maximal incremental exercise

    Secondary Outcome Measures

    Full Information

    First Posted
    March 29, 2022
    Last Updated
    March 29, 2022
    Sponsor
    St Mary's University College
    search

    1. Study Identification

    Unique Protocol Identification Number
    NCT05313932
    Brief Title
    The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise
    Official Title
    The Effects of Partial Sleep Restriction on Physiological and Perceptual Responses During Submaximal and Maximal Exercise in Trained Runners
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    March 2022
    Overall Recruitment Status
    Not yet recruiting
    Study Start Date
    April 20, 2022 (Anticipated)
    Primary Completion Date
    August 31, 2022 (Anticipated)
    Study Completion Date
    September 26, 2022 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Sponsor
    Name of the Sponsor
    St Mary's University College

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No

    5. Study Description

    Brief Summary
    Sleep deprivation has been found to impact exercise performance. The effects of both partial (several hours) and full (24+ hours) sleep deprivation on exercise performance has shown effects on rating of perceived exertion, rate of oxygen consumption, respiratory exchange ratio, and heart rate. A common practice with athletes is to perform regular physiological testing (submaximal and maximal) in order to assess their fitness and to determine training intensities. However, the effects of sleep deprivation on those same physiological test results has not been investigated Therefore, the purpose of this study is to investigate the effects of partial sleep deprivation on physiological test results.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Sleep Deprivation

    7. Study Design

    Primary Purpose
    Basic Science
    Study Phase
    Not Applicable
    Interventional Study Model
    Crossover Assignment
    Masking
    None (Open Label)
    Allocation
    Randomized
    Enrollment
    12 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    Sleep deprivation
    Arm Type
    Experimental
    Arm Description
    Two hours of sleep deprivation (Six hours of sleep)
    Arm Title
    No intervention
    Arm Type
    No Intervention
    Arm Description
    No sleep deprivation (Eight hours of sleep)
    Intervention Type
    Other
    Intervention Name(s)
    Sleep deprivation
    Intervention Description
    Participants wake after six hours so that they are deprived of 2 hours of sleep
    Primary Outcome Measure Information:
    Title
    Oxygen uptake
    Description
    Change from baseline in oxygen uptake measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days
    Title
    Respiratory exchange ratio
    Description
    Change from baseline in respiratory exchange ratio measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days
    Title
    Breathing frequency
    Description
    Change from baseline in breathing frequency measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days
    Title
    Minute ventilation
    Description
    Change from baseline in minute ventilation measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days
    Title
    Blood lactate concentration
    Description
    Change from baseline in blood lactate concentration measured using capillary puncture during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days
    Title
    Rating of perceived exertion
    Description
    Change from baseline in ratings of perceived exertion measured using a 15-point (6-20) scale during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days
    Title
    Heart rate
    Description
    Change from baseline in heart rate measured using a heart rate monitor during submaximal and maximal incremental exercise
    Time Frame
    From baseline to completion, up to 31 days

    10. Eligibility

    Sex
    Male
    Minimum Age & Unit of Time
    18 Years
    Maximum Age & Unit of Time
    45 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: Injury-free, trained, male runners Exclusion Criteria: Female, untrained, injured

    12. IPD Sharing Statement

    Plan to Share IPD
    No

    Learn more about this trial

    The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise

    We'll reach out to this number within 24 hrs