The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis
Primary Purpose
Osteoarthritis, Knee
Status
Completed
Phase
Not Applicable
Locations
Canada
Study Type
Interventional
Intervention
home exercise program for the hip abductor muscles
Sponsored by
About this trial
This is an interventional treatment trial for Osteoarthritis, Knee focused on measuring osteoarthritis, knee, gait, muscle strength, hip, exercise
Eligibility Criteria
Inclusion Criteria:
- age greater than or equal to 40 years
- self-reported pain in the knee(s) for most days of the month
- at least some difficulty in daily function due to knee osteoarthritis
- radiographic evidence of knee osteoarthritis or documented evidence of cartilage loss in the knee by arthroscopy surgery or magnetic resonance imaging.
Exclusion Criteria:
- corticosteroid injection into either knee within the previous three months
- other significant medical problems (including significant heart disease, stroke and active treatment for cancer) that would prevent participants from being able to perform a hip exercise program or to participate in tests of walking performance and hip muscle strength
- known osteoarthritis or previous trauma affecting one or both hips
- previous replacement of any joint in the lower extremities.
- receiving rehabilitation services for knee osteoarthritis or performing a hip strengthening program at the time of testing
- participants who have had a dual-energy x-ray absorptiometry (DEXA) for bone density analysis or more than one x-ray of the chest, abdomen or hip in the past 6 months
Sites / Locations
- School of Rehabilitation Therapy, Queen's University
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Exercise Home-Based Program
Arm Description
Patients with knee OA will be taught a home-based exercise program for the hip abductor muscles during the initial visit. The exercise program will be performed 3 times per week for 8 weeks.
Outcomes
Primary Outcome Measures
Walking variables: hip and knee abductor and adductor moments
Muscle strength measures: isometric and isokinetic peak torque measures for the hip abductor and adductor muscles
Secondary Outcome Measures
Radiographs: lower limb frontal plane alignment measures - limb alignment in degrees; grading of knee osteoarthritis severity (total score out of 13)
Speed of performance on the Five-Times-Sit-to-Stand Test
Total score on the WOMAC pain subscale and the WOMAC physical function subscale
Total score obtained for the physical activity scale (PASE)
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT00427843
Brief Title
The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis
Official Title
The Influence of a Home Program of Hip Abductor Exercises on Gait Parameters and Muscle Strength in Persons With Knee Osteoarthritis
Study Type
Interventional
2. Study Status
Record Verification Date
October 2008
Overall Recruitment Status
Completed
Study Start Date
January 2007 (undefined)
Primary Completion Date
May 2008 (Actual)
Study Completion Date
September 2008 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
Queen's University
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The purpose of this study is to determine the influence of a home program of exercises for the hip muscles which support the pelvis on walking patterns and hip muscle strength in people with knee osteoarthritis. Following a hip muscle strengthening program, we hypothesize that participants with knee osteoarthritis will demonstrate decreased loading at the knee joint during walking and greater strength of the hip muscles.
Detailed Description
Knee osteoarthritis is a common age-related impairment that may progress to cause significant pain and physical disability. Excessive loading at the knee joint is believed to contribute to the progression of knee osteoarthritis. The hip joint and surrounding muscles have been shown to influence the amount of stress occurring at the knee joint during walking. In particular, the hip abductor muscles may have an effect on the knee joint by controlling the position of the pelvis and/or by acting as lateral stabilizers for the knee.
Research suggests that the function of the hip muscles during walking may be decreased in people with knee osteoarthritis and that greater loads may be placed on the knee joint as a result. Thus, interventions aimed at strengthening the hip abductor muscles may be effective for reducing stress on the arthritic knee and slowing the rate of progression of knee osteoarthritis.
The design of the study is a two-group pretest-posttest design using an untreated control group. Thirty-five individuals with medial compartment knee osteoarthritis will be recruited through newspaper advertisements and from the practices of orthopedic surgeons in Kingston, Ontario. Each participant with knee osteoarthritis will be matched with an asymptomatic volunteer for age (+/- 5 years), height (+/- 5 cm), mass (+/- 5 kg) and gender. Participants in the control group will have no clinical or radiographic diagnosis of knee or hip osteoarthritis or rheumatoid arthritis and no history of hip or knee trauma or pain.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Osteoarthritis, Knee
Keywords
osteoarthritis, knee, gait, muscle strength, hip, exercise
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
80 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Exercise Home-Based Program
Arm Type
Experimental
Arm Description
Patients with knee OA will be taught a home-based exercise program for the hip abductor muscles during the initial visit. The exercise program will be performed 3 times per week for 8 weeks.
Intervention Type
Behavioral
Intervention Name(s)
home exercise program for the hip abductor muscles
Intervention Description
All patients with knee OA will be taught a home-based exercise program for the hip abductor muscles during the initial visit. Patients will be instructed in the following program: contraction of the gluteus medius muscle during functional activities (gait, stepping sideways up on a step and standing on one leg); and side lying isotonic hip abduction exercises using graded resistance elastic bands positioned around the distal thighs.
The program will be performed 3 times per week for 8 weeks and subjects will record exercise frequency and level of resistance on exercise calendars. Follow-up visits will occur at the end of week 1 and week 4 for review and progression of exercises. A telephone follow-up call will occur for support and participants will be encouraged to call with any questions or concerns.
Primary Outcome Measure Information:
Title
Walking variables: hip and knee abductor and adductor moments
Time Frame
baseline and after 8 weeks
Title
Muscle strength measures: isometric and isokinetic peak torque measures for the hip abductor and adductor muscles
Time Frame
baseline and after 8 weeks
Secondary Outcome Measure Information:
Title
Radiographs: lower limb frontal plane alignment measures - limb alignment in degrees; grading of knee osteoarthritis severity (total score out of 13)
Time Frame
baseline
Title
Speed of performance on the Five-Times-Sit-to-Stand Test
Time Frame
baseline and after 8 weeks
Title
Total score on the WOMAC pain subscale and the WOMAC physical function subscale
Time Frame
baseline and after 8 weeks
Title
Total score obtained for the physical activity scale (PASE)
Time Frame
baseline and after 8 weeks
10. Eligibility
Sex
All
Minimum Age & Unit of Time
40 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
age greater than or equal to 40 years
self-reported pain in the knee(s) for most days of the month
at least some difficulty in daily function due to knee osteoarthritis
radiographic evidence of knee osteoarthritis or documented evidence of cartilage loss in the knee by arthroscopy surgery or magnetic resonance imaging.
Exclusion Criteria:
corticosteroid injection into either knee within the previous three months
other significant medical problems (including significant heart disease, stroke and active treatment for cancer) that would prevent participants from being able to perform a hip exercise program or to participate in tests of walking performance and hip muscle strength
known osteoarthritis or previous trauma affecting one or both hips
previous replacement of any joint in the lower extremities.
receiving rehabilitation services for knee osteoarthritis or performing a hip strengthening program at the time of testing
participants who have had a dual-energy x-ray absorptiometry (DEXA) for bone density analysis or more than one x-ray of the chest, abdomen or hip in the past 6 months
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Elsie G. Culham, PhD
Organizational Affiliation
Queen's University
Official's Role
Study Director
Facility Information:
Facility Name
School of Rehabilitation Therapy, Queen's University
City
Kingston
State/Province
Ontario
ZIP/Postal Code
K7L 3N6
Country
Canada
12. IPD Sharing Statement
Citations:
PubMed Identifier
20378679
Citation
Sled EA, Khoja L, Deluzio KJ, Olney SJ, Culham EG. Effect of a home program of hip abductor exercises on knee joint loading, strength, function, and pain in people with knee osteoarthritis: a clinical trial. Phys Ther. 2010 Jun;90(6):895-904. doi: 10.2522/ptj.20090294. Epub 2010 Apr 8.
Results Reference
derived
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The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis
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