The National CT Colonography Trial (ACRIN6664)
Colorectal Cancer
About this trial
This is an interventional screening trial for Colorectal Cancer focused on measuring colon cancer, rectal cancer
Eligibility Criteria
Inclusion Criteria Male or female outpatients Aged 50 years or older Scheduled for screening colonoscopy Participant's signed informed consent Exclusion Criteria Symptoms of disease of the lower gastrointestinal tract, including Melanotic stools or/and hematochezia on more than one occasion in the previous six months Lower abdominal pain that would normally require a medical evaluation Inflammatory bowel disease and/or familial polyposis syndrome Serious medical conditions that would increase the risk associated with colonoscopy or are so severe that screening would have no benefit Pregnancy Previous colonoscopy within the past five years Anemia (hemoglobin less than 10 gm/dl) Positive fecal occult blood test (FOBT)
Sites / Locations
- Mayo Clinic Scottsdale
- Moores UCSD Cancer Center
- Jonsson Comprehensive Cancer Center at UCLA
- Veterans Affairs Medical Center - San Francisco
- Invision/Radiology Imaging Associates - Englewood
- Yale Cancer Center
- University of Chicago Cancer Research Center
- Clinical Radiologists, S.C. at Memorial Medical Center
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Beth Israel Deaconess Medical Center
- Mayo Clinic Cancer Center
- Mallinckrodt Institute of Radiology at Washington University Medical Center
- M.D. Anderson Cancer Center at University of Texas
- Virginia Commonwealth University Massey Cancer Center
Arms of the Study
Arm 1
Experimental
CT Colonography
CT colonography conducted during the same assessment as colonoscopy.