The Pilot Study of Medical Device-Neuclare for Patients With Mild Cognitive Disorder and Early Dementia

Inclusion Criteria: Adults aged 55 to 90 Patients who meet "Probable Alzheimer's disease" and "Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV)" criteria for dementia Patients with CDR (clinical dementia rating) from 0.5 to 1 and MMSE-II over 18 Upon hearing and fully understanding the detailed explanation of this clinical trial, a person who has voluntarily decided to participate and agreed in writing to comply with the precautions Exclusion Criteria: Patient with pathological lesions in the brain identified by MRI Patients with metabolic disorders such as thyroid dysfunction, hyperglycemia, hypoglycemia, liver or kidney dysfunction, and long-term use of drugs that will cause cognitive decline (e.g., anticholinergic drugs) History of epileptic seizures or depression or psychiatric abnormalities or with visual acuity and fluctuations in cognitive decline History of psychiatric disorder other than the inclusion criteria. A person with a severe history of cancer/tuberculosis A person who has or is taking psychiatric or peripheral/central nervous system drugs A person who has contact dermatitis or sensitive skin abnormalities Patients with a high fever of 40 degrees or higher based on eardrum body temperature A person whose bleeding is identified within the last 3 months due to a common procedure/surgery that may affect vital signs A person who is unable to perform MRI tests Pregnant women Patient with calcification in the brain identified by CT Patient with allergic to contrast agents such as Definity or Gadovist Other cases where the investigator judged that it is difficult to participate in the study;