The Psychological Treatment of Overweight Binge Eaters Minority Supplement
Primary Purpose
Binge Eating Disorder, Cognitive Therapy/Methods, Mental Disorders/Epidemiology
Status
Completed
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
Cognitive Behavioral Therapy (CBT)
Interpersonal Therapy (IPT)
Sponsored by
About this trial
This is an interventional treatment trial for Binge Eating Disorder focused on measuring Body Mass Index, Bulimia/therapy, Comorbidity, Interpersonal Relations, Psychotherapy/methods
Eligibility Criteria
Inclusion Criteria:
- DSM-IV research criteria for binge-eating disorder
- Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
- Marked stress regarding binge eating
- At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
- 18-65 years old
- Body mass index, 27-48 kg/m squared
Exclusion Criteria:
- Pregnant or planning to become pregnant
- Taking weight-affecting or psychotropic medications
- Psychiatric conditions warranting immediate treatment
- Current enrollment in psychotherapy or a weight loss program
Sites / Locations
- Yale University
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Binge Eating Disorder/Therapy
Arm Description
Outcomes
Primary Outcome Measures
Short and long-term efficacy of two treatments for binge eating among the overweight: Group Cognitive-Behavior (CBT) and Group Interpersonal Therapy (IPT).
Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at post treatment, and at 4-month intervals up to 12 months following treatment.
Secondary Outcome Measures
Full Information
NCT ID
NCT01208259
First Posted
August 31, 2010
Last Updated
September 24, 2010
Sponsor
Washington University School of Medicine
1. Study Identification
Unique Protocol Identification Number
NCT01208259
Brief Title
The Psychological Treatment of Overweight Binge Eaters Minority Supplement
Official Title
A Randomized Comparison of Group-Behavioral Therapy and Group Interpersonal Psychotherapy for the Treatment of Overweight Individuals With Binge-Eating Disorder Minority Supplement
Study Type
Interventional
2. Study Status
Record Verification Date
September 2010
Overall Recruitment Status
Completed
Study Start Date
April 1997 (undefined)
Primary Completion Date
March 1999 (Actual)
Study Completion Date
March 1999 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
Washington University School of Medicine
4. Oversight
5. Study Description
Brief Summary
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED.
Detailed Description
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED. METHODS: One hundred sixty-two overweight patients meeting DSM-IV criteria for BED were randomly assigned to 20 weekly sessions of either group CBT or group IPT. Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at posttreatment, and at 4-month intervals up to 12 months following treatment. RESULTS: Binge-eating recovery rates were equivalent for CBT and IPT at posttreatment (64 [79%] of 81 vs 59 [73%] of 81) and at 1-year follow-up (48 [59%] of 81 vs 50 [62%] of 81). Binge eating increased slightly through follow-up but remained significantly below pretreatment levels. Across treatments, patients had similar significant reductions in associated eating disorders and psychiatric symptoms and maintenance of gains through follow-up. Dietary restraint decreased more quickly in CBT but IPT had equivalent levels by later follow-ups. Patients' relative weight decreased significantly but only slightly, with the greatest reduction among patients sustaining recovery from binge eating from posttreatment to 1-year follow-up. CONCLUSIONS: Group IPT is a viable alternative to group CBT for the treatment of overweight patients with BED. Although lacking a nonspecific control condition limits conclusions about treatment specificity, both treatments showed initial and long-term efficacy for the core and related symptoms of BED.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Binge Eating Disorder, Cognitive Therapy/Methods, Mental Disorders/Epidemiology, Obesity/Epidemiology, Obesity/Therapy
Keywords
Body Mass Index, Bulimia/therapy, Comorbidity, Interpersonal Relations, Psychotherapy/methods
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 1, Phase 2
Interventional Study Model
Parallel Assignment
Masking
Participant
Allocation
Randomized
Enrollment
162 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Binge Eating Disorder/Therapy
Arm Type
Experimental
Intervention Type
Behavioral
Intervention Name(s)
Cognitive Behavioral Therapy (CBT)
Intervention Type
Behavioral
Intervention Name(s)
Interpersonal Therapy (IPT)
Primary Outcome Measure Information:
Title
Short and long-term efficacy of two treatments for binge eating among the overweight: Group Cognitive-Behavior (CBT) and Group Interpersonal Therapy (IPT).
Description
Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at post treatment, and at 4-month intervals up to 12 months following treatment.
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
DSM-IV research criteria for binge-eating disorder
Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
Marked stress regarding binge eating
At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
18-65 years old
Body mass index, 27-48 kg/m squared
Exclusion Criteria:
Pregnant or planning to become pregnant
Taking weight-affecting or psychotropic medications
Psychiatric conditions warranting immediate treatment
Current enrollment in psychotherapy or a weight loss program
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Denise E Wilfley, Ph.D.
Organizational Affiliation
Washington University School of Medicine
Official's Role
Principal Investigator
Facility Information:
Facility Name
Yale University
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06511-3516
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
12150647
Citation
Wilfley DE, Welch RR, Stein RI, Spurrell EB, Cohen LR, Saelens BE, Dounchis JZ, Frank MA, Wiseman CV, Matt GE. A randomized comparison of group cognitive-behavioral therapy and group interpersonal psychotherapy for the treatment of overweight individuals with binge-eating disorder. Arch Gen Psychiatry. 2002 Aug;59(8):713-21. doi: 10.1001/archpsyc.59.8.713.
Results Reference
result
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The Psychological Treatment of Overweight Binge Eaters Minority Supplement
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