The Recovery of Cardiovascular Patients With Depression
Coronary Artery Disease, Depression, Cardiovascular Diseases
About this trial
This is an interventional treatment trial for Coronary Artery Disease focused on measuring Brain derived neurotrophic factor, BDNF, Psychosocial indicators, Depression, Cardiovascular disease
Eligibility Criteria
Inclusion Criteria:
- patients on day of percutaneous coronary intervention due to angina pectoris or myocardial infarction
- without antidepressant drugs or major tranquilizers more than one year
Exclusion Criteria:
- symptoms of myocardial infarction lasting more than 12 hours
- left ventricle ejection function (LVEF) less than 40%
- earlier presence of cardiomyopathy
- acute infection
Sites / Locations
- KBC ZagrebRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
No Intervention
Experimental
Intervention I
Control
Intervention II
Psychiatric treatment with sertraline (range from 50 mg/day to 200mg/day according to clinical appearance) of cardiovascular patients after PCI with mild, moderate or severe depression
Cardiovascular patients after PCI without depressive symptoms and without the need for psychiatric intervention
Psychiatric treatment with escitalopram (range from 10 mg/day to 20 mg/day according to clinical appearance) of cardiovascular patients after PCI with mild, moderate or severe depression