The Role of Lifestyle Factors in Breast Cancer-Related Outcomes
Stage II Breast Cancer AJCC v6 and v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7
About this trial
This is an interventional supportive care trial for Stage II Breast Cancer AJCC v6 and v7
Eligibility Criteria
Inclusion Criteria:
- Women with stage II or III breast cancer that will be scheduled to undergo a 4 to 6-week course of radiotherapy
- Participants must be able to read, write, and speak English
- Participants must be oriented to person, place, and time
- Participants must also meet at least two of the following criteria related to lifestyle: 1) consume less than 3 servings of fruit and vegetable/day; 2) engage in less than 75 minutes moderate/vigorous activity per week, defined as anything that causes small increases in breathing or heart rate for a sustained amount of time (e.g., brisk walking, bicycling); and 3) engage in a mind-body practice less than 4 times a month
- Participants must have a body mass index (BMI) of 24.45 or higher as assessed in the medical record
Exclusion Criteria:
- Patients with a recurrent breast cancer diagnosis
- Patients with another primary cancer diagnosis within 5 years of consent, not including non-melanoma skin cancers
- Patients who have any major psychiatric diagnoses or thought disorder (e.g. schizophrenia, bi-polar disorder, dementia)
- Patients with communication barriers (e.g., hard of hearing)
- Patients with extreme mobility issues (e.g. unable to get in and out of a chair unassisted)
- Patients with poorly or uncontrolled diabetes in the opinion of the physician(s)
Sites / Locations
- M D Anderson Cancer Center
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Arm I (IO interventions)
Arm II (standard of care)
Patients undergo up to 7 different IO intervention sessions per week during their 6-week course of radiotherapy for between 1 and 3 hours each session, in addition to, up to 6 aerobic training sessions per week and one grocery store trip during the course of the program. IO intervention programs consist of nutritional coaching, behavioral therapy, yoga and meditation practice, resistance training, and a weekly meal sharing and cooking class. Patients then have weekly meetings with the study psychologist on the computer for 6 months, followed by a monthly meeting on the computer from 6-12 months, and 2 hour meetings at all follow-up appointments during the first year after radiotherapy.
Patients undergo standard of care.