The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment
HIV Infections
About this trial
This is an interventional treatment trial for HIV Infections focused on measuring HIV-1, Drug Therapy, Combination, HIV Protease Inhibitors, Ritonavir, Indinavir, Reverse Transcriptase Inhibitors, Anti-HIV Agents, Viral Load, Nelfinavir
Eligibility Criteria
Inclusion Criteria Patients may be eligible for this study if they: Are HIV-positive. Are 18 years of age or older. Have a CD4 cell count of at least 50 cells/mm3. Have a viral load (level of HIV in the blood) of at least 400 copies/ml but no more than 20,000 copies/ml. Have had an initial response to protease inhibitor therapy with a viral load of less than 400 copies/ml in two consecutive tests at least 1 week apart. Have been on anti-HIV (antiretroviral) treatment including indinavir or nelfinavir for at least 16 weeks. Have had virologic failure (two consecutive viral loads that were greater than or equal to 400 copies/ml and less than or equal to 20,000 copies/ml at least 1 week apart) that is not due to another infection, vaccination, or a temporary stop in treatment. Are naive to at least one of the selected NRTIs.
Sites / Locations
- Pacific Oaks Research
- Ocean View Internal Medicine
- Bisher Akil
- Tower Infectious Diseases / Med Associates Inc
- UCSD Med Ctr - Owen Clinic
- HIV Institute / Davies Med Ctr
- San Francisco Veterans Adm Med Cntr
- Avalar Medical Group
- Harbor - UCLA Med Ctr
- Benjamin Young
- University of Connecticut Health Center
- IDC Research Initiative
- Hillsborough County Health Dept
- Mercer University School of Medicine
- Thomas Coffman MD
- Chicago Ctr for Clinical Research
- Northwestern Univ / Infect Dis Div / Pasavant Pav 828
- The CORE Ctr
- Univ of Kansas School of Medicine
- University of Louisville / ID Division
- Tulane Univ School of Medicine
- Institute of Human Virology
- New England Med Ctr
- Cooper Hospital Early Intervention Program
- Dr Ronald Nahass
- Bronx Veterans Affairs Med Ctr
- Mt Vernon Hosp
- Gramercy Park Physicians LLP
- St Luke Roosevelt Hosp
- St Vincents Hosp / Clinical Research Program
- Bellevue Hosp Ctr
- Mount Sinai Med Ctr
- SUNY at Stony Brook / Div of Infectious Disease
- Wake Forest Univ School of Medicine
- Oklahoma Univ Health Science Ctr
- Fanno Creek Clinic
- Anderson Clinical Research
- Univ of Texas Med Branch / Div of Infectious Dis
- Thomas Street Clinic
- Univ of Texas Health Sciences Ctr