The Safety and Efficacy of Micro-energy Ultrasound in the Treatment of Renal Insufficiency After Renal Transplantation

The Safety and Efficacy of Micro-energy Ultrasound in the Treatment of Renal Insufficiency After Renal Transplantation

The Safety and Efficacy of Micro-energy Ultrasound in the Treatment of Renal Insufficiency After Renal Transplantation: A Multicenter, Randomized Clinical Trail

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, First Affiliated Hospital of Wenzhou Medical University

The safety and efficacy of micro-energy ultrasound in the treatment of renal insufficiency after renal transplantation.

Study purposes: To evaluate the safety and efficacy of micro-energy ultrasound in the treatment of renal dysfunction after renal transplantation by measuring serum creatinine, urine volume, urea nitrogen, and transplanted kidney ultrasound, etc. Study design: This is a randomized, double-blind, controlled, multicenter clinical trial. Study objects: Patients with mild to moderate renal insufficiency after renal transplantation. Number of samples: 90 Main study center: Department of Urology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Treatments: Test group: After installing the disposable treatment head coat, the transplanted kidney was treated with an ultrasonic therapeutic apparatus; after the treatment, the disposable treatment head coat was removed.Patients were treated twice a week for 6 weeks. Control group: The placebo was treated with an ultrasound therapy device and used in the same manner as the test group.

After installing the disposable treatment head coat, the transplanted kidney was treated with an ultrasonic therapeutic apparatus; after the treatment, the disposable treatment head coat was removed. Patients were treated twice a week for 6 weeks.

The placebo was treated with an ultrasound therapy device and used in the same manner as the test group.

After installing the disposable treatment head coat, the transplanted kidney was treated with an ultrasonic therapeutic apparatus; after the treatment, the disposable treatment head coat was removed. Patients were treated twice a week for 6 weeks.

The placebo was treated with an ultrasound therapy device and used in the same manner as the test group.

Inclusion Criteria: More than half a year after renal transplantation, serum creatinine elevated over three times , patients with ineffective immunosuppressive drugs; Mild to moderate renal insufficiency (creatinine less than 442umol / L); Volunteer to participate in this clinical trial, comply with the requirements of this clinical trial and sign the informed consent form. Exclusion Criteria: Patients with severe renal insufficiency; Blood routine suggests acute and chronic blood system diseases; B-ultrasound suggests transplanting hydronephrosis; Uncontrollable patients with diabetes, hypertension, and cardiovascular disease; The investigator determined that it is not suitable for this clinical trial.