Back to resultsThe Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position
Primary Purpose
Acute Lung Injury, Acute Respiratory Distress Syndrome
Status
Completed
Phase
Not Applicable
Locations
Italy
Study Type
Interventional
Intervention
specific elastance
Sponsored by
About this trial
This is an interventional treatment trial for Acute Lung Injury focused on measuring Gas exchange, Respiratory mechanics, Ventilator Induced Lung Injury
Eligibility Criteria
Inclusion Criteria:
- ALI/ARDS patients during invasive mechanical ventilation
Exclusion Criteria:
- Haemodynamic failure, pneumothorax
Sites / Locations
- Policlinico Hospital
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
1
Arm Description
Outcomes
Primary Outcome Measures
Specific elastance
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT00568659
Brief Title
The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position
Official Title
The Specific Lung Elastance in ALI/ARDS Patients in Supine and Prone Position
Study Type
Interventional
2. Study Status
Record Verification Date
April 2015
Overall Recruitment Status
Completed
Study Start Date
December 2007 (undefined)
Primary Completion Date
November 2010 (Actual)
Study Completion Date
January 2015 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Policlinico Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The investigators aim is to study the specific lung elastance in ALI/ARDS patients during invasive mechanical ventilation, in supine and prone position.
Detailed Description
In sedated and paralyzed ALI/ARDS patients, we study and compare the specific lung elastance in supine and prone position during invasive mechanical ventilation.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Acute Lung Injury, Acute Respiratory Distress Syndrome
Keywords
Gas exchange, Respiratory mechanics, Ventilator Induced Lung Injury
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
15 (Actual)
8. Arms, Groups, and Interventions
Arm Title
1
Arm Type
Experimental
Intervention Type
Procedure
Intervention Name(s)
specific elastance
Intervention Description
The investigators study the specific lung elastance in ALI/ARDS patients in supine and prone position.
Primary Outcome Measure Information:
Title
Specific elastance
Time Frame
5 minutes
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
ALI/ARDS patients during invasive mechanical ventilation
Exclusion Criteria:
Haemodynamic failure, pneumothorax
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Davide Chiumello, MD
Organizational Affiliation
Policlinico Hospital
Official's Role
Principal Investigator
Facility Information:
Facility Name
Policlinico Hospital
City
Milano
ZIP/Postal Code
20122
Country
Italy
12. IPD Sharing Statement
Learn more about this trial
The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position
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