Three-dimensional Ultrasonography Thyroid Volume Measurement.

The purpose of this clinical trial is to investigate the accuracy of applying three-dimensional ultrasound on thyroid gland patients when determining a gland volume. The method will be compared to conventional b-mode ultrasound where three axis measurements (length, width, and depth) are evaluated in the ellipsoid model. The three dimensional (3D) method is utilizing optical tracking connected to the ultrasound image to form cross-sectional imaging. Patients enrolled in the study are set for complete thyroidectomies enabling a true volume of the gland by water displacement after excision. The aim is to find if this 3D method is more accurate in volume estimation than the ellipsoid model.

Obtaining thyroid volume with 2D ultrasound (length x Width x depth*(Pi/6)) and 3D ultrasound with optical tracking and comparing the respective methods with a reference volume. Water displacement being gold standard for reference volume.

Inclusion Criteria: Patients referred to Rigshospitalet to undergo a complete thyroidectomy including patients with previous hemithyroidectomy Adults, 18 or older. Ability to give written informed consent Exclusion Criteria: Thyroid glands that are too enlarged causing visualization/measurement impairment with ultrasonography. Thyroid cancer with preoperative suspected extracapsular spread. Thyroids or lymph nodes that need frozen section examination.

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