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Time Course Effects of Functional Resistance Training on Fitness and Quality of Life Chronic Low Back Pain Patients

Primary Purpose

Chronic Low-back Pain

Status
Completed
Phase
Not Applicable
Locations
Pakistan
Study Type
Interventional
Intervention
functional resistance training GROUP A
functional resistance training GROUP B
Sponsored by
Riphah International University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Chronic Low-back Pain focused on measuring Pain, disability, strength, quality of life, functional resistance training

Eligibility Criteria

25 Years - 45 Years (Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Patient having low back pain as a primary complaint, without associated leg pain;
  • Chronic pain (>= 3 months, >= 3 days/week)
  • non- specific (soft tissue in origin)
  • Patient having no history of formal exercise training.
  • Learning proper technique under expert supervision
  • Postural stability (static/dynamic)

Exclusion Criteria:

  • Receiving concurrent treatments from another practitioner for LBP
  • Congenital deformities of spine
  • Neurological conditions (neuropathy, radiculopathy)
  • Musculoskeletal conditions (fractures, atrophy, weakness)
  • Cardiovascular, Nephrological conditions
  • Contraindications to exercise
  • Involved in workers' compensation claims;
  • Medications other than analgesics and NSAIDS

Sites / Locations

  • Pakistan Railway General Hospital

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Experimental

Arm Label

functional resistance training GROUP A

functional resistance training GROUP B

Arm Description

Session of 45-60 min starting with Warm Up Exercise and stretching prior to therapy and cool-down and stretching after the training sessions

Session of 45-60 min starting with Warm Up Exercise and stretching prior to therapy and cool-down and stretching after the training sessions

Outcomes

Primary Outcome Measures

Visual analogue scale (VAS)for pain:
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain. it is scientifically evident that VAS is a reliable and valid scale in aged more than 18 years. In many studies it is proved that VAS is a reliable scale but for validity it showed moderate to strong correlation for pain measurement. assessment to be done at base line after 6 weeks and after detraining of 6 weeks
Visual analogue scale (VAS)for pain:
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain. it is scientifically evident that VAS is a reliable and valid scale in aged more than 18 years. In many studies it is proved that VAS is a reliable scale but for validity it showed moderate to strong correlation for pain measurement. assessment to be done at base line after 12 weeks and after detraining of 12 weeks
Oswestry Disability Index (ODI) for disability:
Each section is scored on a 0-5 scale, 5 representing the greatest disability. The index is calculated by dividing the summed score by the total possible score, which is then multiplied by 100 and expressed as a percentage. Thus, for every question not answered, the denominator is reduced by 5. The ODI can be used to assess both chronic and acute conditions of varying severity. It has high test-retest reliability and takes around 5min for a patient to complete. assessment to be done at base line after 6 weeks and after detraining of 6 weeks.
Oswestry Disability Index (ODI) for disability:
Each section is scored on a 0-5 scale, 5 representing the greatest disability. The index is calculated by dividing the summed score by the total possible score, which is then multiplied by 100 and expressed as a percentage. Thus, for every question not answered, the denominator is reduced by 5. The ODI can be used to assess both chronic and acute conditions of varying severity. It has high test-retest reliability and takes around 5min for a patient to complete. assessment to be done at base line after 12 weeks and after detraining of 12 weeks.
SHORT FORM-36 for HRQOL
The Short form -36 covers eight different dimensions of HRQOL: physical functioning, social functioning, role limitations due to physical functioning (role functioning-physical), bodily gain, general mental health, role limitations due to emotional functioning (role functioning-emotional), vitality (energy and fatigue), and general health perception. Scores can be summed together from all domains with differing weightings to contribute to two summary scores, a physical component score and a mental component score. The study findings indicate that the SF-36 is a reliable and valid instrument for assessment of HRQoL in patients. assessment to be done at base line after 6 weeks and after detraining of 6 weeks.
SF-36 for HRQOL
The SF-36 covers eight different dimensions of HRQOL: physical functioning, social functioning, role limitations due to physical functioning (role functioning-physical), bodily gain, general mental health, role limitations due to emotional functioning (role functioning-emotional), vitality (energy and fatigue), and general health perception. Scores can be summed together from all domains with differing weightings to contribute to two summary scores, a physical component score and a mental component score. The study findings indicate that the SF-36 is a reliable and valid instrument for assessment of HRQoL in patients. assessment to be done at base line after 12 weeks and after detraining of 12 weeks.

Secondary Outcome Measures

Physical fitness with flamingo test
The Flamingo Balance Test is total body balance test, and forms part of the Eurofit Testing Battery. This single leg balance test assesses the strength of the leg, pelvic, and trunk muscle as well as dynamic balance. purpose: To assess the ability to balance successfully on a single leg. assessment to be done at base line after 6 weeks and after detraining of 6 weeks.
Physical fitness with flamingo test
The Flamingo Balance Test is total body balance test, and forms part of the Testing Battery. This single leg balance test assesses the strength of the leg, pelvic, and trunk muscle as well as dynamic balance. purpose: To assess the ability to balance successfully on a single leg. assessment to be done at base line after 12 weeks and after detraining of 12 weeks
physical fitness with back endurance test:
The starting position is the patient/client adopting a half prone lying on a plinth with the superior edge of the iliac crest at the edge of the plinth and the arms crossed over the chest. The lower limbs are strategically stabilized with straps. The patient/client is asked to maintains the upper body in a horizontal position and the timer is started. The test ends if the patient/client can maintain the said position for 4 minutes or can no longer maintain the set position before 4 minutes elapses. The stop time is recorded. Assesment to be done at baseline after 6 weeks and detraining of 6 weeks.
physical fitness with back endurance test:
The starting position is the patient/client adopting a half prone lying on a plinth with the superior edge of the iliac crest at the edge of the plinth and the arms crossed over the chest. The lower limbs are strategically stabilized with straps. The patient/client is asked to maintains the upper body in a horizontal position and the timer is started. The test ends if the patient/client can maintain the said position for 4 minutes or can no longer maintain the set position before 4 minutes elapses. The stop time is recorded. Assessment to be done at baseline after 12 weeks and detraining of 12 weeks.
physical function with side bridge test
The trunk lateral endurance test, also called the side-bridge test, assesses muscular endurance of the lateral core muscles (i.e., transverse abdominis, obliques, quadratus lumborum, and erector spinae). This timed test involves static, isometric contractions of the lateral muscles on each side of the trunk that stabilize the spine. Assessment to be done at baseline after 6 weeks and detraining after 6 weeks.
physical function with side bridge test
The trunk lateral endurance test, also called the side-bridge test, assesses muscular endurance of the lateral core muscles (i.e., transverse abdominis, obliques, quadratus lumborum, and erector spinae). This timed test involves static, isometric contractions of the lateral muscles on each side of the trunk that stabilize the spine. Assessment to be done at baseline after 12 weeks and detraining after 12weeks.
physical function with abdominal curl-up test
The curl up test measures abdominal muscular strength and endurance of the abdominals and hip-flexors, important in back support and core stability. assessment to be done at baseline after 6 weeks and detraining after 6 weeks.
physical function with abdominal curl-up test
The curl up test measures abdominal muscular strength and endurance of the abdominals and hip-flexors, important in back support and core stability. assessment to be done at baseline after 12 weeks and detraining after 12 weeks.
physical function with 60-s squat test:
To test lower body muscle endurance. Perform for the greatest possible number of repetitions in 1 min without carrying out assisted movements using other body segments assessment to be done at baseline after 6 weeks and detraining after 6 weeks.
physical function with 60-s squat test:
To test lower body muscle endurance. Perform for the greatest possible number of repetitions in 1 min without carrying out assisted movements using other body segments assessment to be done at baseline after 12 weeks and detraining after 12 weeks.
Biofeedback pressure unit
The unit consists of a combined gauge and inflation bulb connected to a pressure cell. Designed by physical therapists, the Stabilizer registers changing pressure in an air-filled pressure cell allowing body movements to be detected during exercise. The Pressure Biofeedback Unit is a reliable tool when utilized with a population of subjects that can perform the abdominal drawing-in test. assessment to be done at baseline after 6 weeks and detraining after 6 weeks
Biofeedback pressure unit
The unit consists of a combined gauge and inflation bulb connected to a pressure cell. Designed by physical therapists, the Stabilizer registers changing pressure in an air-filled pressure cell allowing body movements to be detected during exercise. The Pressure Biofeedback Unit is a reliable tool when utilized with a population of subjects that can perform the abdominal drawing-in test. Assessment to be done at baseline after 12 weeks and detraining after 12 weeks

Full Information

First Posted
July 4, 2022
Last Updated
September 14, 2022
Sponsor
Riphah International University
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1. Study Identification

Unique Protocol Identification Number
NCT05449262
Brief Title
Time Course Effects of Functional Resistance Training on Fitness and Quality of Life Chronic Low Back Pain Patients
Official Title
Time Course Effects of Functional Resistance Training on Fitness and Quality of Life in Patients With Nonspecific Chronic Low-back Pain
Study Type
Interventional

2. Study Status

Record Verification Date
September 2022
Overall Recruitment Status
Completed
Study Start Date
April 30, 2022 (Actual)
Primary Completion Date
August 1, 2022 (Actual)
Study Completion Date
August 5, 2022 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Riphah International University

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
Low back pain is categorized according to its duration as acute (<6 weeks), sub-acute (6 weeks - 12 weeks) and chronic (>12 weeks). Low back pain can be either specific or non-specific. Specific low back pain is because of specific spinal pathologies including; Malignancy, Infection, Osteoporotic Collapse, Fracture, Ankylosing Spondylitis or other inflammatory disorders and Cauda equina compression. About 19 in 20 cases of acute (sudden onset) low back pain are classed as 'non-specific' It is called 'non-specific' because it is usually not clear what is actually causing the pain or there is no specific problem or disease that can be identified as to the cause of the pain.Functional Resistance Training (FRT) involves multiplanar and multi joint resistance exercises that simulate movement patterns from everyday life and sport Functional training exercises tend to focus more on the coordination, technique, posture, and core engagement instead of on training loads.
Detailed Description
The lower back is also called the 'lumbosacral area' of the back. It is the part of the back between the bottom of the ribs and the top of the legs and is made up of the spine bones (vertebrae), discs, nerves, muscles and ligaments. Pain in this region is called low back pain. (1) Low back pain is categorized according to its duration as acute (<6 weeks), sub-acute (6 weeks - 12 weeks) and chronic (>12 weeks). About 19 in 20 cases of acute (sudden onset) low back pain are classed as 'non-specific' It is called 'non-specific' because it is usually not clear what is actually causing the pain or there is no specific problem or disease that can be identified as to the cause of the pain. It is said that cause may be a sprain (an over-stretch) of a ligament or muscle, minor problem with the disc between two vertebrae, or a minor problem with a small 'facet' joint between two vertebrae. It is not possible to identify these causes of the pain by tests. Therefore, it is usually impossible to say exactly where the pain is coming from, or exactly what is causing the pain. Sometimes a pain may develop immediately after lifting something heavy, or after an awkward twisting movement. Sometimes it can develop for no apparent reason. Some people just wake up one day with low back pain. Typically the pain is in one area of the lower back, but sometimes it spreads to one or both buttocks or thighs. Non-specific low back pain is 'mechanical' in the sense that it varies with posture or activity. In a small number of cases the pain persists for several months or longer. This is called chronic back pain. There is no test that can prove or confirm non-specific low back pain. Non-specific low back pain is classed as chronic (persistent) if it lasts longer than six weeks. In some people it lasts for months, or even years. Symptoms may be constant. Non-specific low back pain affects people of all ages and is a leading contributor to disease burden worldwide. The ACSM defines functional RT (FRT) as activities involving multiple muscle, joint, and planar activities that are closely related to activities of daily living, combining upper and lower body movements to use more of the body in each movement. Few studies have examined FRT, though initial results suggest that FRT is associated with higher caloric expenditure and similar muscular strength, endurance, and gains in flexibility compared with a TRT program. Functional training is becoming increasingly popular within the fitness industry and has been considered to be a better alternative than traditional resistance training for improving various measures of muscular fitness including strength, endurance, coordination and balance. The verb form of the word "function" pertains to the performance of an action, work or activity. Thus, exercise training programs that are deemed to be "functional" should be designed to mimic tasks or activities that occur in a person's daily life to make training adaptations more transferable. Engaging in regular RT provides physical, physiological and psychological health benefits while providing additional bone health benefits. Although RT has greatly increased in popularity, other types of training aside from traditional RT (TRT) have yet to be examined. One such type of training, ''functional fitness,'' is defined by the ACSM as the use of strength training to improve balance and ease of living, and was in the top 10 fitness trends in 2018. Functional Resistance Training (FRT) involves multiplanar and multi joint resistance exercises that simulate movement patterns from everyday life and sport Functional training exercises tend to focus more on the coordination, technique, posture, and core engagement instead of on training loads. The goal of FRT is not hypertrophy but to promote a potential motor problem in order to train dynamic stabilization. Appropriate functional exercises are those in which the lumbo-pelvic region remains aligned within the neutral zone by co-contraction of the muscles of the trunk, while other demands executed with the extremities are simultaneously and successfully fulfilled. This method of training usually includes: a) spinal stabilization exercises; b) balance and proprioceptive exercises; c) flexibility exercises; d) resistance training exercises. Functional RT may be more feasible and accessible due to the minimal equipment needed and the flexibility to be performed in and out of a typical gym setting.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Chronic Low-back Pain
Keywords
Pain, disability, strength, quality of life, functional resistance training

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
36 (Actual)

8. Arms, Groups, and Interventions

Arm Title
functional resistance training GROUP A
Arm Type
Experimental
Arm Description
Session of 45-60 min starting with Warm Up Exercise and stretching prior to therapy and cool-down and stretching after the training sessions
Arm Title
functional resistance training GROUP B
Arm Type
Experimental
Arm Description
Session of 45-60 min starting with Warm Up Exercise and stretching prior to therapy and cool-down and stretching after the training sessions
Intervention Type
Other
Intervention Name(s)
functional resistance training GROUP A
Intervention Description
Session of 45-60 min. Warm up prior to training Warm up 6-7 min of mild cardiovascular exercise followed by 3-4 min stretching Cool down post training A cool-down of 1 min of mild cardiovascular exercise followed by 4 min of stretching
Intervention Type
Other
Intervention Name(s)
functional resistance training GROUP B
Intervention Description
Session of 45-60 min Warm up prior to training Warm up 6-7 min of mild cardiovascular exercise followed by 3-4 min stretching Cool down post training A cool-down of 1 min of mild cardiovascular exercise followed by 4 min of stretching
Primary Outcome Measure Information:
Title
Visual analogue scale (VAS)for pain:
Description
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain. it is scientifically evident that VAS is a reliable and valid scale in aged more than 18 years. In many studies it is proved that VAS is a reliable scale but for validity it showed moderate to strong correlation for pain measurement. assessment to be done at base line after 6 weeks and after detraining of 6 weeks
Time Frame
6 weeks
Title
Visual analogue scale (VAS)for pain:
Description
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain. it is scientifically evident that VAS is a reliable and valid scale in aged more than 18 years. In many studies it is proved that VAS is a reliable scale but for validity it showed moderate to strong correlation for pain measurement. assessment to be done at base line after 12 weeks and after detraining of 12 weeks
Time Frame
12 weeks
Title
Oswestry Disability Index (ODI) for disability:
Description
Each section is scored on a 0-5 scale, 5 representing the greatest disability. The index is calculated by dividing the summed score by the total possible score, which is then multiplied by 100 and expressed as a percentage. Thus, for every question not answered, the denominator is reduced by 5. The ODI can be used to assess both chronic and acute conditions of varying severity. It has high test-retest reliability and takes around 5min for a patient to complete. assessment to be done at base line after 6 weeks and after detraining of 6 weeks.
Time Frame
6 weeks
Title
Oswestry Disability Index (ODI) for disability:
Description
Each section is scored on a 0-5 scale, 5 representing the greatest disability. The index is calculated by dividing the summed score by the total possible score, which is then multiplied by 100 and expressed as a percentage. Thus, for every question not answered, the denominator is reduced by 5. The ODI can be used to assess both chronic and acute conditions of varying severity. It has high test-retest reliability and takes around 5min for a patient to complete. assessment to be done at base line after 12 weeks and after detraining of 12 weeks.
Time Frame
12 weeks
Title
SHORT FORM-36 for HRQOL
Description
The Short form -36 covers eight different dimensions of HRQOL: physical functioning, social functioning, role limitations due to physical functioning (role functioning-physical), bodily gain, general mental health, role limitations due to emotional functioning (role functioning-emotional), vitality (energy and fatigue), and general health perception. Scores can be summed together from all domains with differing weightings to contribute to two summary scores, a physical component score and a mental component score. The study findings indicate that the SF-36 is a reliable and valid instrument for assessment of HRQoL in patients. assessment to be done at base line after 6 weeks and after detraining of 6 weeks.
Time Frame
6 weeks
Title
SF-36 for HRQOL
Description
The SF-36 covers eight different dimensions of HRQOL: physical functioning, social functioning, role limitations due to physical functioning (role functioning-physical), bodily gain, general mental health, role limitations due to emotional functioning (role functioning-emotional), vitality (energy and fatigue), and general health perception. Scores can be summed together from all domains with differing weightings to contribute to two summary scores, a physical component score and a mental component score. The study findings indicate that the SF-36 is a reliable and valid instrument for assessment of HRQoL in patients. assessment to be done at base line after 12 weeks and after detraining of 12 weeks.
Time Frame
12 weeks
Secondary Outcome Measure Information:
Title
Physical fitness with flamingo test
Description
The Flamingo Balance Test is total body balance test, and forms part of the Eurofit Testing Battery. This single leg balance test assesses the strength of the leg, pelvic, and trunk muscle as well as dynamic balance. purpose: To assess the ability to balance successfully on a single leg. assessment to be done at base line after 6 weeks and after detraining of 6 weeks.
Time Frame
6 weeks
Title
Physical fitness with flamingo test
Description
The Flamingo Balance Test is total body balance test, and forms part of the Testing Battery. This single leg balance test assesses the strength of the leg, pelvic, and trunk muscle as well as dynamic balance. purpose: To assess the ability to balance successfully on a single leg. assessment to be done at base line after 12 weeks and after detraining of 12 weeks
Time Frame
12 weeks
Title
physical fitness with back endurance test:
Description
The starting position is the patient/client adopting a half prone lying on a plinth with the superior edge of the iliac crest at the edge of the plinth and the arms crossed over the chest. The lower limbs are strategically stabilized with straps. The patient/client is asked to maintains the upper body in a horizontal position and the timer is started. The test ends if the patient/client can maintain the said position for 4 minutes or can no longer maintain the set position before 4 minutes elapses. The stop time is recorded. Assesment to be done at baseline after 6 weeks and detraining of 6 weeks.
Time Frame
6 weeks
Title
physical fitness with back endurance test:
Description
The starting position is the patient/client adopting a half prone lying on a plinth with the superior edge of the iliac crest at the edge of the plinth and the arms crossed over the chest. The lower limbs are strategically stabilized with straps. The patient/client is asked to maintains the upper body in a horizontal position and the timer is started. The test ends if the patient/client can maintain the said position for 4 minutes or can no longer maintain the set position before 4 minutes elapses. The stop time is recorded. Assessment to be done at baseline after 12 weeks and detraining of 12 weeks.
Time Frame
12 weeks
Title
physical function with side bridge test
Description
The trunk lateral endurance test, also called the side-bridge test, assesses muscular endurance of the lateral core muscles (i.e., transverse abdominis, obliques, quadratus lumborum, and erector spinae). This timed test involves static, isometric contractions of the lateral muscles on each side of the trunk that stabilize the spine. Assessment to be done at baseline after 6 weeks and detraining after 6 weeks.
Time Frame
6 weeks
Title
physical function with side bridge test
Description
The trunk lateral endurance test, also called the side-bridge test, assesses muscular endurance of the lateral core muscles (i.e., transverse abdominis, obliques, quadratus lumborum, and erector spinae). This timed test involves static, isometric contractions of the lateral muscles on each side of the trunk that stabilize the spine. Assessment to be done at baseline after 12 weeks and detraining after 12weeks.
Time Frame
12 weeks
Title
physical function with abdominal curl-up test
Description
The curl up test measures abdominal muscular strength and endurance of the abdominals and hip-flexors, important in back support and core stability. assessment to be done at baseline after 6 weeks and detraining after 6 weeks.
Time Frame
6 weeks
Title
physical function with abdominal curl-up test
Description
The curl up test measures abdominal muscular strength and endurance of the abdominals and hip-flexors, important in back support and core stability. assessment to be done at baseline after 12 weeks and detraining after 12 weeks.
Time Frame
after 12 weeks
Title
physical function with 60-s squat test:
Description
To test lower body muscle endurance. Perform for the greatest possible number of repetitions in 1 min without carrying out assisted movements using other body segments assessment to be done at baseline after 6 weeks and detraining after 6 weeks.
Time Frame
6 weeks
Title
physical function with 60-s squat test:
Description
To test lower body muscle endurance. Perform for the greatest possible number of repetitions in 1 min without carrying out assisted movements using other body segments assessment to be done at baseline after 12 weeks and detraining after 12 weeks.
Time Frame
12 weeks
Title
Biofeedback pressure unit
Description
The unit consists of a combined gauge and inflation bulb connected to a pressure cell. Designed by physical therapists, the Stabilizer registers changing pressure in an air-filled pressure cell allowing body movements to be detected during exercise. The Pressure Biofeedback Unit is a reliable tool when utilized with a population of subjects that can perform the abdominal drawing-in test. assessment to be done at baseline after 6 weeks and detraining after 6 weeks
Time Frame
6 weeks
Title
Biofeedback pressure unit
Description
The unit consists of a combined gauge and inflation bulb connected to a pressure cell. Designed by physical therapists, the Stabilizer registers changing pressure in an air-filled pressure cell allowing body movements to be detected during exercise. The Pressure Biofeedback Unit is a reliable tool when utilized with a population of subjects that can perform the abdominal drawing-in test. Assessment to be done at baseline after 12 weeks and detraining after 12 weeks
Time Frame
12 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
25 Years
Maximum Age & Unit of Time
45 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Patient having low back pain as a primary complaint, without associated leg pain; Chronic pain (>= 3 months, >= 3 days/week) non- specific (soft tissue in origin) Patient having no history of formal exercise training. Learning proper technique under expert supervision Postural stability (static/dynamic) Exclusion Criteria: Receiving concurrent treatments from another practitioner for LBP Congenital deformities of spine Neurological conditions (neuropathy, radiculopathy) Musculoskeletal conditions (fractures, atrophy, weakness) Cardiovascular, Nephrological conditions Contraindications to exercise Involved in workers' compensation claims; Medications other than analgesics and NSAIDS
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Maria Khalid, MSOMPT
Organizational Affiliation
Riphah International University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Pakistan Railway General Hospital
City
Rawalpindi
State/Province
Punjab
ZIP/Postal Code
46000
Country
Pakistan

12. IPD Sharing Statement

Plan to Share IPD
No

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Time Course Effects of Functional Resistance Training on Fitness and Quality of Life Chronic Low Back Pain Patients

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