To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure Patients
Liver Cirrhosis, Acute on Chronic Liver Failure
About this trial
This is an interventional treatment trial for Liver Cirrhosis
Eligibility Criteria
Inclusion Criteria: - All Cirrhosis and/or ACLF patients >18 yrs, scheduled to undergo an high risk invasive procedure with severe coagulopathy requiring correction as per risk category and degree of coagulopathy on conventional coagulation tests. Exclusion Criteria: Ongoing bleeding Bleeding within last 3 days ACLF patients going for LT may be added in exclusion criteria Antiplatelet or anticoagulant therapy (discontinued <7 d before) Hemodialysis in last 3 days
Sites / Locations
- Institute of Liver & Biliary SciencesRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Relaxed rotational thromboelastometry
Standard coagulation tests
Relaxed rotational thromboelastometry will be done 12 hr,24 hr,48 hr, 72 hr and if patients bleed.
Standard coagulation tests will be done baseline,12 hr,24 hr,48 hr, 72 hr and if patients bleed