To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan
Polio, Polio Sero Conversion, Polio Sero Prevalence
About this trial
This is an interventional prevention trial for Polio focused on measuring Polio disease, Intervention Package, Polio sero prevalence and sero conversion, Polio high risk areas of Pakistan
Eligibility Criteria
Inclusion Criteria:
- Healthy children aged 1 month to 5 years that reside within the study sites, and do not plan to travel away during entire the study period.
Exclusion Criteria:
- Children with known thrombocytopenia or bleeding disorders; children acutely ill or with signs of acute infection (e.g. fever ≥ 101 F) at the time of NID and a diagnosis or suspicion of immunodeficiency disorder.
Sites / Locations
- Aga Khan University
Arms of the Study
Arm 1
Arm 2
Arm 3
No Intervention
Experimental
Experimental
Group A
Group B
Group C
Routine Polio Program activities will be carried out with out any active intervention
Expanded intervention with following components Community support groups for both male and female at village/community level Enhanced communication package and involvement of local social networks for group counseling on promotion of nutrition, hygiene and Expanded Program of Immunization (EPI) vaccinations Involvement of Private sector (General Physicians,health care providers etc.) through advocacy and inclusion in Supplementary Immunization activities (SIAs) Delivery of interventions & commodities through low cost health camps during National Immunization days (NIDs) and SIAs (will also assist in mop-up campaigns)
All Interventions of Group A and B Plus combined bOPV/IPV strategy in the SIAs during the project