Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
Acute Pain
About this trial
This is an interventional treatment trial for Acute Pain focused on measuring Elderly, Hydromorphone, Morphine, Pain, Acute, Emergency Department
Eligibility Criteria
Inclusion Criteria: Age greater than 65 years Pain with onset within 7 days ED attending physician's judgment that patient's pain warrants use of parenteral opioids Normal mental status Exclusion Criteria: Prior use of methadone Use of other opioids or tramadol within past seven days Prior adverse reaction to morphine or hydromorphone Chronic pain syndrome Alcohol intoxication Systolic Blood Pressure <90 mm Hg Use of monoamine oxidase (MAO) inhibitors in past 30 days Elderly patients with a capnometry reading of greater than 46
Sites / Locations
- Montefiore Medical Center
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Hydromorphone
Morphine
0.0075 mg/kg IV hydromorphone
0.05 mg/kg IV morphine