Trivalent rHA Dose Escalation Study in Elderly Subjects
Influenza
About this trial
This is an interventional prevention trial for Influenza focused on measuring Influenza, Baculovirus, Immunogenicity, Geriatrics
Eligibility Criteria
Inclusion Criteria: Medically stable adult age 65 -80. Able to give informed consent. Able to comply with all study procedures. Community dwelling. Exclusion Criteria: History of immunodeficiency or treatment with immunosuppressive medications. (use of inhaled steroids or of topical steroids is not considered immunosuppressive). Allergy to eggs, egg proteins, thimerosal, or other vaccine components. Acute febrile illness or upper respiratory tract illness within 72 hours of vaccination. Life expectancy less than 6 months. Use of experimental vaccines or medications within one month of study entry. Receipt of parenteral immunoglobulin within one month of study entry. Any acute or chronic condition which in the opinion of the investigator would render vaccination unsafe or interfere with the evaluation of response.
Sites / Locations
- University of Rochester
- Cincinnati Children's Hospital Medical Center
- Baylor College of Medicine