Ultra-Violet Fluorescence Bronchial Cancer Location (UVFBCL)

Diagnose lung cancer at an early stage is crucial for effective treatment. At these early stages, cancer is usually invisible in ambient white light when the endoscopic analysis of the bronchial mucosa. This lining is self-fluorescent at its illumination by blue light. These widely distributed autofluorescence methods detect early mucosal abnormalities. They are very sensitive but not specific to recognize the lung cancer. Thanks to European funding (EURIMUS), a new tool with fluorescent UV light has been developed. The purpose of this preliminary study is to verify the suitability for specific detection of cancerous tissue in Pneumology of this fluorescence method versus histological analysis of the tissue.

Detection of cancerous tissues and healthy or inflammatory tissues is used to calculate the sensitivity and specificity of the rigid bronchoscopy with UV transmission compared to biopsy (gold standard).

Inclusion Criteria: Patient affiliated or entitled to a social security scheme Major Patient Patient who signed the informed consent document Patient with a known primary cancer in bronchial level Exclusion Criteria: Pregnant woman Patient with a benign tumor histology Patient with an unknown tumor histology.