Ultrafiltration Versus Intravenous (IV) Diuretics for Patients Hospitalized for Acute Decompensated Heart Failure: (UNLOAD)
Congestive Heart Failure
About this trial
This is an interventional treatment trial for Congestive Heart Failure focused on measuring Ultrafiltration, acute decompensated heart failure, fluid overload, pulmonary congestion
Eligibility Criteria
Inclusion Criteria: Patients hospitalized with primary diagnosis of acute decompensated congestive heart failure (adCHF) Evidence of fluid overload as indicated by: pitting edema (2+) of lower extremities; jugular venous distension; pulmonary edema or pleural effusion; ascites; paroxysmal nocturnal dyspnea or 2-pillow orthopnea Exclusion Criteria: Acute coronary syndrome Creatinine greater than 3.0 Systolic blood pressure less than or equal to 90 mmHg Hematocrit greater than 45% Prior administration of IV vasoactive drugs in the emergency room (ER) Clinical instability requiring pressors during hospitalization Recent use of iodinated contrast material Severe concomitant disease expected to prolong hospitalization Sepsis On or requires renal dialysis Had a cardiac transplant Heparin allergy
Sites / Locations
- Midwest Heart Institute