Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures
Meibomian Gland Dysfunction, Cataract, Glaucoma
About this trial
This is an interventional diagnostic trial for Meibomian Gland Dysfunction
Eligibility Criteria
Inclusion Criteria:
- For patients with meibomian gland dysfunction (MGD):
MGD as evidenced by clinical features and gland expression (MGD Grading Scheme, Appendix I (Opitz, Harthan et al. 2015))
- For cataract patients:
Cataract as evidenced from slit lamp examination, stage range between NII-NIII, CII-CIV, PII-PIII according to The Lens Opacity Classification System II (LOCS II) (Chylack, Leske et al. 1989) (Appendix II)
- For patients after minimally invasive glaucoma surgery (MIGS):
Patients with history of MIGS secondary to glaucoma
- For patients with demodicosis:
Demodicosis as evidenced from slit lamp examination and presence of Demodex confirmed by microscopic examination of the eye lashes (Liu, Sheha et al. 2010)
- For patients with conjunctival pathologies (cyst, naevus, pterygium):
Conjunctival pathologies with a clinical diagnosis of the respective
- For patients with Acanthamoeba keratitis:
Acanthamoeba keratitis as evidenced from slit lamp examination and confirmed by polymerase chain reaction (PCR) analysis of corneal epithelial and tear samples and culture isolation (Lehmann, Green et al. 1998)
- For aniridia patients:
Anirida as evidenced from slit lamp examination
Exclusion Criteria:
- Presence of any abnormalities preventing reliable measurements as judged by the investigator
- Pregnancy, planned pregnancy or lactating
Sites / Locations
- Medical University Vienna, Department of Clnical Pharmacology
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Arm 8
Other
Other
Other
Other
Other
Other
Other
Other
10 patients with meibomian gland dysfunction
10 patients with cataract
10 patients after minimally invasive glaucoma surgery (MIGS)
10 patients after partial corneal transplantation
5 patients with demodicosis
5 patients with conjunctival pathologies
5 patients with Acanthamoeba keratitis
5 patients with aniridia