Back to resultsUse of Multiphoton Microscopy in the Diagnosis of Cancer (MPM)
Primary Purpose
Bladder Cancer, Prostate Cancer
Status
Completed
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
Multiphoton microscopy
Sponsored by
About this trial
This is an interventional diagnostic trial for Bladder Cancer focused on measuring Bladder cancer, prostate cancer, multiphoton microscopy
Eligibility Criteria
Inclusion Criteria:
- Anyone who presents with bladder and/or prostate cancer
Sites / Locations
- Weill Cornell Medical College
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
MPM
Arm Description
Subject tissue was reviewed using multiphoton microscopy
Outcomes
Primary Outcome Measures
After several delays, the multiphoton microscope has been delivered to Weill Cornell Medical College. We have been using this time to set-up and fine tune the multiphoton microscope. As of current, no negative events have occurred.
Secondary Outcome Measures
Full Information
NCT ID
NCT00652210
First Posted
March 31, 2008
Last Updated
December 8, 2015
Sponsor
Weill Medical College of Cornell University
1. Study Identification
Unique Protocol Identification Number
NCT00652210
Brief Title
Use of Multiphoton Microscopy in the Diagnosis of Cancer
Acronym
MPM
Official Title
Use of Multiphoton Microscopy in the Diagnosis of Cancer
Study Type
Interventional
2. Study Status
Record Verification Date
December 2015
Overall Recruitment Status
Completed
Study Start Date
June 2005 (undefined)
Primary Completion Date
September 2015 (Actual)
Study Completion Date
September 2015 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Weill Medical College of Cornell University
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Multiphoton microscopy (MPM) has been shown to be able to image tissue at a cellular level. Our project will initially evaluated the ability of MPM imaging to distinguish normal bladder urothelium from atypical and malignant urothelium in the ex vivo setting. After development of sufficient criteria, we plan to develop an endoscopic bladder probe that will provide a non-invasive means to image the interior of the bladder at the cellular level, which would provide direct evidence of the presence of tumor without a biopsy. After exhibiting usefulness of MPM imaging for bladder cancer, we will look at other organs beginning with the colon.
Detailed Description
Same as above
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Bladder Cancer, Prostate Cancer
Keywords
Bladder cancer, prostate cancer, multiphoton microscopy
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Phase 1
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
344 (Actual)
8. Arms, Groups, and Interventions
Arm Title
MPM
Arm Type
Experimental
Arm Description
Subject tissue was reviewed using multiphoton microscopy
Intervention Type
Other
Intervention Name(s)
Multiphoton microscopy
Intervention Description
Use of multiphoton microscopy to diagnose cancer
Primary Outcome Measure Information:
Title
After several delays, the multiphoton microscope has been delivered to Weill Cornell Medical College. We have been using this time to set-up and fine tune the multiphoton microscope. As of current, no negative events have occurred.
Time Frame
10/14/2007 to 2/15/2008
10. Eligibility
Sex
All
Minimum Age & Unit of Time
21 Years
Maximum Age & Unit of Time
85 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Anyone who presents with bladder and/or prostate cancer
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Douglas S Scherr, M.D.
Organizational Affiliation
Weill Medical College of Cornell University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Weill Cornell Medical College
City
New York
State/Province
New York
ZIP/Postal Code
10065
Country
United States
12. IPD Sharing Statement
Learn more about this trial
Use of Multiphoton Microscopy in the Diagnosis of Cancer
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