Validation of Algorithms for Basal Insulin Rate Reductions in Type 1 Diabetic Patients Practising Physical Activity (DIABRASPORT)
Type 1 Diabetes With a Subcutaneous Insulin Pump, Adjustment of the Recommended Basal Insulin Flow Rate in the Event of Physical Activity, Adjustment of the Recommended Prandial Insulin in the Event of Physical Activity
About this trial
This is an interventional basic science trial for Type 1 Diabetes With a Subcutaneous Insulin Pump focused on measuring Algorithm basal insulin, physical activity, Type 1 diabetes, Insulin pump treatment
Eligibility Criteria
Inclusion Criteria:
- Patients aged over 18 years, presenting type 1 diabetes for at least 1 year
- Patients on basal-prandial regimen treated with functional insulin therapy
- Patients with a subcutaneous insulin pump for at least 3 months
- Patients with HbA1c < 9% less than 3 months before
- Patients with stable basal flow for at least 1 week
- Patients able to pedal
- Patients covered by social security
- Patients consenting to take part in the study and having signed a written informed consent form.
Exclusion Criteria:
- Patients with a history of severe hypoglycaemia in the 6 months prior to entry into the study
- Patients unable to detect their hypoglycaemia
- Patients with perforating foot ulcer or a known history of heart disease or obliterative arteriopathy of the lower limbs, or a history of cerebrovascular accident, or ongoing proliferative retinopathy or renal failure.
- Patients with poorly controlled hypertension
- Women either pregnant or likely to become pregnant
- Patients deprived of liberty by judicial or administrative decision, patients placed under legal guardianship.
Sites / Locations
- Centre Hospitalier Sud Francilien
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Other
Other
Other
Other
Other
50% VO2 max, BFR reduced by 50%
50% VO2 max,BFR reduced by 80%
75% VO2 max, BFR reduced by 80%
75% VO2 max, pump switched off
Rest
The basal rate of the pump will be adjusted in accordance with the intensity of physical activity being performed for moderate physical activity (50% VO2max),a temporary basal rate will be reduced by 50%
The basal rate of the pump will be adjusted in accordance with the intensity of physical activity being performed for moderate physical activity (50% VO2max),a temporary basal rate will be reduced by 80%
The basal rate of the pump will be adjusted in accordance with the intensity of physical activity being performed for moderate physical activity (75% VO2max),a temporary basal rate will be reduced by 80%.
Turning off the pump (75%VO2max TBR100).However, in order to maintain the study blindfold, the pump will be switched off but not removed.
Patient will be in rest, basal insulin flow rate will not be change.