Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2) (VIEWS-2)
Stroke
About this trial
This is an interventional treatment trial for Stroke focused on measuring acute, walking deficits
Eligibility Criteria
Inclusion Criteria: Sub-acute stroke (1-6 months) Hemiparesis (Fugl-Meyer <34) without cerebellar deficits Ability to ambulate with or without physical assistance over 10 meters but < 1.0 m/s and assistive devices and below-knee bracing is allowed. Ability to sit > 30 seconds without upper-extremity support or physical assistance Ability to follow 3-step commands Provision of informed consent and medical clearance from a supervising physician or medical provider to participate Must have the ability to consent or have a legal health care power of attorney or legally authorized representative to consent for participation on their behalf Exclusion Criteria: Significant cardiovascular, metabolic, or respiratory disease that limits exercise participation (e.g. previous myocardial infarction < 3 months prior, uncompensated congestive heart failure, resting blood pressure > 210/110 mmHg, uncontrolled diabetes, end-stage renal disease, severe infectious or psychiatry disease, or advanced malignancy) If during the graded-treadmill exercise evaluation, the participant presents with absolute criteria for termination of exercise testing during initial testing (e.g. moderate to severe angina, ST elevation > 1.0mm without preexisting Q wave secondary to prior MI, signs of poor perfusion, etc). Any orthopedic or neurological disorders that limited walking to <50m prior to stroke onset. Cannot receive physical therapy once baseline testing begins If patients are prescribed botulinum toxin for their lower extremities will be excluded only if the dosage for any specific muscle is >50 units in leg muscles above the knee. If doses are > than 50 units in leg muscles below the knee, the participant will use an ankle-foot orthosis to minimze contributions of those mscles to locomotor function.
Sites / Locations
- Rehabilitation Hospital of IndianaRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
Active Comparator
Active Comparator
High-intensity, task-specific (i.e., walking) interventions
High-intensity, non-specific physical therapy interventions
Low-intensity, task-specific physical therapy interventions
Low-intensity, non-specific physical therapy interventions
30 1-hr sessions of walking training targeting higher cardiovascular intensities over approximately 2 months
30 1-hr sessions of general physical therapy interventions (strengthening, balance training, aerobic cycling, transfers, walking) targeting higher cardiovascular intensities over approximately 2 months
30 1-hr sessions of general physical therapy interventions (strengthening, balance training, aerobic cycling, transfers, walking) targeting lower cardiovascular intensities over approximately 2 months
30 1-hr sessions of general physical therapy interventions (strengthening, balance training, aerobic cycling, transfers, walking) targeting lower cardiovascular intensities over approximately 2 months