Vascular Occlusion for Optimizing Functional Improvement in Patients With Knee Osteoarthritis (VOFIKO)
Blood Flow Restriction
About this trial
This is an interventional treatment trial for Blood Flow Restriction focused on measuring Blood Flow Restriction, Strength training, Knee Osteoarthritis
Eligibility Criteria
Inclusion Criteria:
- Diagnosed with knee osteoarthritis
- Speak Dutch, French or English
- No other pathology restricting patients to participate safe
- Time and motivation to visit 2x/w for 12 weeks
Exclusion Criteria:
- Neurological disorders
- previous surgery or disorder with blood vessels.
- (Symptomatic) heart or vascular disease
- Increased risk for DVT
- Avoiding physical exercise due to medical conditions.
- Rheumatoid arthritis
- BMI >30
- Recent severe trauma or surgery in the lower extremity
Sites / Locations
- Ghent UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Sham Comparator
Active Comparator
Blood flow restriction group
Sham group
Control group
patients in this group will undergo a standard strength training program combined with an occlusion cuff. The cuff will reduce the amount of blood flow and therefore increase the metabolic stimulus. The cuff will be used only during one quadriceps exercise, 2 times a week for 12 weeks.
patients in this group will undergo the same standard strength training program as the BFR-group, combined with an occlusion cuff but pressurized so there is no significant effect on the lower limb blood flow. The cuff will be used only during one quadriceps exercise, 2 times a week for 12 weeks.
patients in this group will undergo the same standard strength training program as the BFR-group and placebo-group, but without a tourniquet.