Vocal Cord vs Whole Laryngeal Radiotherapy for T1aN0 Glottic Cancer (VC-Larynx)
Larynx Cancer Stage I, Glottic Carcinoma
About this trial
This is an interventional treatment trial for Larynx Cancer Stage I focused on measuring Larynx, Glottic, T1, hypofractionated radiotherapy, Vocal cord, Laryngeal carcinoma
Eligibility Criteria
Inclusion Criteria: T10N0 glottic squamous cell carcinoma Ability to provide written informed consent Eastern Cooperative Oncology Group performance status 0-2 Exclusion Criteria: Previous head and neck irradiation. WHO performance status above 2.
Sites / Locations
- National Cancer Institute, Cairo UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Single vocal cord hypofractionated radiotherapy
Whole laryngeal radiotherapy
Hypofractionated radiotherapy 58.08Gy/16 fractions to affected vocal cord plus margins to account for motion and setup errors using IMRT/VMAT technique
Radiotherapy 63Gy/28 fractions to whole larynx from lower border of hyoid bone to lower border of cricoid cartilage using IMRT/VMAT technique