Weight Loss and Exercise for Communities With Arthritis in North Carolina (WE-CAN)
Osteoarthritis
About this trial
This is an interventional treatment trial for Osteoarthritis focused on measuring Knee Pain, Exercise, Diet, Weight Loss
Eligibility Criteria
Inclusion Criteria:
- age ≥ 50
- Knee Pain plus American College of Rheumatology (ACR) Criteria for Knee Osteoarthritis
- BMI = 27 ≥ kg/m2
Exclusion Criteria:
- Significant co-morbid disease that would threaten safety or impair ability to participate in interventions or testing (Blindness; Type 1 diabetes; Severe coronary artery disease)
- Not sufficiently overweight or obese, BMI < 27 kg/m2
- Not having knee pain
- Inability to finish 18-month study or unlikely to be compliant (Planning to leave area > 2 month during the next 18 months; Unwilling to change eating or physical activity habits; Unwilling to discontinue pain medication use for 3 days prior to testing visit)
- Age, age < 50
- Other conditions that may prohibit the effective delivery of the intervention (Unable to provide own transportation to exercise center; Unable to read or write)
Sites / Locations
- Johnston County - UNC Chapel Hill
- Haywood County - Haywood Regional Medical Center
- Forsyth County - Wake Forest University/Wake Forest University Health Sciences
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Diet & Exercise
Attention Control
Participants will attend an exercise class 3 days/week for 18 months. The exercise program will consist of a 15-minute aerobic phase, a 20-minute strength training phase, a second 15-minute aerobic phase, and a 10 minute cool down phase. Participant's will also attend individual and group diet sessions. Each participant's minimum weight loss goal will be 10% of baseline body weight.
The attention control intervention will cover an 18-month period. There will be five total face to face group meetings over the 18 months, with one meeting each at months 1, 3, 6, 9, and 15; and during the other months (months 2-5, 7-11, 13-17) participants will receive a combination of informational packets, webinars, phone sessions, and/or emails based on continued monitoring of participant needs and delivered via their preferred mode of contact.