What is the Dose Response of Varying Meal Content of Fat on Postprandial Glycaemia in Children With T1DM? (REQINSOIL)
Diabetes Mellitus, Type 1
About this trial
This is an interventional basic science trial for Diabetes Mellitus, Type 1 focused on measuring Lipid, Carbohydrate counting, Adolescent, Continuous glucose monitoring, Insulin requirements
Eligibility Criteria
Inclusion Criteria:
- Diagnosed with T1DM for more than 1 year
- HbA1c less than 8%
- BMI less than 91st centile
- on intensive insulin therapy
Exclusion Criteria:
-
Sites / Locations
- Cork University Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Experimental
Experimental
Experimental
Experimental
Placebo Comparator
Active Comparator
Fat Test drink (50g)
Fat Test drink (38g)
Fat Test drink (25g)
Fat Test drink (13g)
Fat Test drink (3g)
Carbohydrate Test drink
This drink contains 50g sunflower oil and vehicle (almond milk, chocolate drink powder, sweetener)
This drink contains 38g sunflower oil and vehicle (almond milk, chocolate drink powder, sweetener)
This drink contains 25g sunflower oil and vehicle (almond milk, chocolate drink powder, sweetener)
This drink contains 13g sunflower oil and vehicle (almond milk, chocolate drink powder, sweetener)
This drink contains no sunflower oil and vehicle (almond milk, chocolate drink powder, sweetener)
This drink contains 20g of glucose from de-gassed lucozade energy.