Working Memory Training Combined With Transcranial Magnetic Stimulation in Smokers
Tobacco Use Disorder
About this trial
This is an interventional treatment trial for Tobacco Use Disorder
Eligibility Criteria
Inclusion Criteria:
- meet safety guidelines for application of rTMS
- be 18-60 years of age
- have smoked cigarettes regularly for at least one year
- currently smoke at least 10 cigarettes per day
- have a carbon monoxide (CO) level >10 ppm
- currently use no other nicotine products regularly
Exclusion Criteria:
- meet criteria for current alcohol or substance dependence
- have a current affective disorder (depression, dysthymia, or mania) or psychotic symptoms
- are currently pregnant or lactating, or intend to become pregnant
- have a health condition for which rTMS is contraindicated
Sites / Locations
- Brown University
- Butler Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
Active Comparator
Sham Comparator
WMT + rTMS
Sham WMT + rTMS
WMT + sham rTMS
Sham WMT + sham rTMS
WMT + rTMS is the Working Memory Training + repetitive Transcranial Magnetic Stimulation arm. Both conditions are active.
Sham WMT + rTMS is the sham Working Memory Training + repetitive Transcranial Magnetic Stimulation arm. This condition isolates the effects of rTMS. WMT is inactive.
WMT + sham rTMS is the Working Memory Training + sham repetitive Transcranial Magnetic Stimulation arm. This condition isolates the effects of WMT. rTMS is inactive.
sham WMT + sham rTMS is the sham Working Memory Training + sham repetitive Transcranial Magnetic Stimulation arm. Both are inactive in this arm.